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466 related items for PubMed ID: 22426395

  • 1. Effects of a tacrine-8-hydroxyquinoline hybrid (IQM-622) on Aβ accumulation and cell death: involvement in hippocampal neuronal loss in Alzheimer's disease.
    Antequera D, Bolos M, Spuch C, Pascual C, Ferrer I, Fernandez-Bachiller MI, Rodríguez-Franco MI, Carro E.
    Neurobiol Dis; 2012 Jun; 46(3):682-91. PubMed ID: 22426395
    [Abstract] [Full Text] [Related]

  • 2. Intracellular amyloid-β accumulation in calcium-binding protein-deficient neurons leads to amyloid-β plaque formation in animal model of Alzheimer's disease.
    Moon M, Hong HS, Nam DW, Baik SH, Song H, Kook SY, Kim YS, Lee J, Mook-Jung I.
    J Alzheimers Dis; 2012 Jun; 29(3):615-28. PubMed ID: 22269161
    [Abstract] [Full Text] [Related]

  • 3. Tauroursodeoxycholic acid suppresses amyloid β-induced synaptic toxicity in vitro and in APP/PS1 mice.
    Ramalho RM, Nunes AF, Dias RB, Amaral JD, Lo AC, D'Hooge R, Sebastião AM, Rodrigues CM.
    Neurobiol Aging; 2013 Feb; 34(2):551-61. PubMed ID: 22621777
    [Abstract] [Full Text] [Related]

  • 4. Novel tacrine-8-hydroxyquinoline hybrids as multifunctional agents for the treatment of Alzheimer's disease, with neuroprotective, cholinergic, antioxidant, and copper-complexing properties.
    Fernández-Bachiller MI, Pérez C, González-Muñoz GC, Conde S, López MG, Villarroya M, García AG, Rodríguez-Franco MI.
    J Med Chem; 2010 Jul 08; 53(13):4927-37. PubMed ID: 20545360
    [Abstract] [Full Text] [Related]

  • 5. Amyloid-beta causes memory impairment by disturbing the JAK2/STAT3 axis in hippocampal neurons.
    Chiba T, Yamada M, Sasabe J, Terashita K, Shimoda M, Matsuoka M, Aiso S.
    Mol Psychiatry; 2009 Feb 08; 14(2):206-22. PubMed ID: 18813209
    [Abstract] [Full Text] [Related]

  • 6. Hippocampal GABAergic neurons are susceptible to amyloid-β toxicity in vitro and are decreased in number in the Alzheimer's disease TgCRND8 mouse model.
    Krantic S, Isorce N, Mechawar N, Davoli MA, Vignault E, Albuquerque M, Chabot JG, Moyse E, Chauvin JP, Aubert I, McLaurin J, Quirion R.
    J Alzheimers Dis; 2012 Feb 08; 29(2):293-308. PubMed ID: 22232004
    [Abstract] [Full Text] [Related]

  • 7. Transplanted astrocytes internalize deposited beta-amyloid peptides in a transgenic mouse model of Alzheimer's disease.
    Pihlaja R, Koistinaho J, Malm T, Sikkilä H, Vainio S, Koistinaho M.
    Glia; 2008 Jan 15; 56(2):154-63. PubMed ID: 18004725
    [Abstract] [Full Text] [Related]

  • 8. Calretinin interneurons are early targets of extracellular amyloid-beta pathology in PS1/AbetaPP Alzheimer mice hippocampus.
    Baglietto-Vargas D, Moreno-Gonzalez I, Sanchez-Varo R, Jimenez S, Trujillo-Estrada L, Sanchez-Mejias E, Torres M, Romero-Acebal M, Ruano D, Vizuete M, Vitorica J, Gutierrez A.
    J Alzheimers Dis; 2010 Jan 15; 21(1):119-32. PubMed ID: 20413859
    [Abstract] [Full Text] [Related]

  • 9. Leptin induces proliferation of neuronal progenitors and neuroprotection in a mouse model of Alzheimer's disease.
    Pérez-González R, Antequera D, Vargas T, Spuch C, Bolós M, Carro E.
    J Alzheimers Dis; 2011 Jan 15; 24 Suppl 2():17-25. PubMed ID: 21335656
    [Abstract] [Full Text] [Related]

  • 10. Neuropathology of mice carrying mutant APP(swe) and/or PS1(M146L) transgenes: alterations in the p75(NTR) cholinergic basal forebrain septohippocampal pathway.
    Jaffar S, Counts SE, Ma SY, Dadko E, Gordon MN, Morgan D, Mufson EJ.
    Exp Neurol; 2001 Aug 15; 170(2):227-43. PubMed ID: 11476589
    [Abstract] [Full Text] [Related]

  • 11. Intracellular Aß triggers neuron loss in the cholinergic system of the APP/PS1KI mouse model of Alzheimer's disease.
    Christensen DZ, Bayer TA, Wirths O.
    Neurobiol Aging; 2010 Jul 15; 31(7):1153-63. PubMed ID: 18771817
    [Abstract] [Full Text] [Related]

  • 12. Accelerated tau pathology with synaptic and neuronal loss in a novel triple transgenic mouse model of Alzheimer's disease.
    Saul A, Sprenger F, Bayer TA, Wirths O.
    Neurobiol Aging; 2013 Nov 15; 34(11):2564-73. PubMed ID: 23747045
    [Abstract] [Full Text] [Related]

  • 13. Running exercise delays neurodegeneration in amygdala and hippocampus of Alzheimer's disease (APP/PS1) transgenic mice.
    Lin TW, Shih YH, Chen SJ, Lien CH, Chang CY, Huang TY, Chen SH, Jen CJ, Kuo YM.
    Neurobiol Learn Mem; 2015 Feb 15; 118():189-97. PubMed ID: 25543023
    [Abstract] [Full Text] [Related]

  • 14. Early neuronal loss and axonal/presynaptic damage is associated with accelerated amyloid-β accumulation in AβPP/PS1 Alzheimer's disease mice subiculum.
    Trujillo-Estrada L, Dávila JC, Sánchez-Mejias E, Sánchez-Varo R, Gomez-Arboledas A, Vizuete M, Vitorica J, Gutiérrez A.
    J Alzheimers Dis; 2014 Feb 15; 42(2):521-41. PubMed ID: 24927710
    [Abstract] [Full Text] [Related]

  • 15. Effects of the superoxide dismutase/catalase mimetic EUK-207 in a mouse model of Alzheimer's disease: protection against and interruption of progression of amyloid and tau pathology and cognitive decline.
    Clausen A, Xu X, Bi X, Baudry M.
    J Alzheimers Dis; 2012 Feb 15; 30(1):183-208. PubMed ID: 22406441
    [Abstract] [Full Text] [Related]

  • 16. Soluble Aβ levels correlate with cognitive deficits in the 12-month-old APPswe/PS1dE9 mouse model of Alzheimer's disease.
    Zhang W, Hao J, Liu R, Zhang Z, Lei G, Su C, Miao J, Li Z.
    Behav Brain Res; 2011 Sep 23; 222(2):342-50. PubMed ID: 21513747
    [Abstract] [Full Text] [Related]

  • 17. Neuropep-1 ameliorates learning and memory deficits in an Alzheimer's disease mouse model, increases brain-derived neurotrophic factor expression in the brain, and causes reduction of amyloid beta plaques.
    Shin MK, Kim HG, Baek SH, Jung WR, Park DI, Park JS, Jo DG, Kim KL.
    Neurobiol Aging; 2014 May 23; 35(5):990-1001. PubMed ID: 24268884
    [Abstract] [Full Text] [Related]

  • 18. Intracellular accumulation of toxic turn amyloid-β is associated with endoplasmic reticulum stress in Alzheimer's disease.
    Soejima N, Ohyagi Y, Nakamura N, Himeno E, Iinuma KM, Sakae N, Yamasaki R, Tabira T, Murakami K, Irie K, Kinoshita N, LaFerla FM, Kiyohara Y, Iwaki T, Kira J.
    Curr Alzheimer Res; 2013 Jan 23; 10(1):11-20. PubMed ID: 22950910
    [Abstract] [Full Text] [Related]

  • 19. The effect of ageing on neurogenesis and oxidative stress in the APP(swe)/PS1(deltaE9) mouse model of Alzheimer's disease.
    Hamilton A, Holscher C.
    Brain Res; 2012 Apr 17; 1449():83-93. PubMed ID: 22418058
    [Abstract] [Full Text] [Related]

  • 20. Intracellular Abeta42 activates p53 promoter: a pathway to neurodegeneration in Alzheimer's disease.
    Ohyagi Y, Asahara H, Chui DH, Tsuruta Y, Sakae N, Miyoshi K, Yamada T, Kikuchi H, Taniwaki T, Murai H, Ikezoe K, Furuya H, Kawarabayashi T, Shoji M, Checler F, Iwaki T, Makifuchi T, Takeda K, Kira J, Tabira T.
    FASEB J; 2005 Feb 17; 19(2):255-7. PubMed ID: 15548589
    [Abstract] [Full Text] [Related]

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