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Journal Abstract Search


101 related items for PubMed ID: 22433003

  • 1. Licofelone inhibits interleukin-18-induced pro-inflammatory cytokine release and cellular proliferation in human mesangial cells.
    Wu YJ, Xue M, Chen H.
    Basic Clin Pharmacol Toxicol; 2012 Sep; 111(3):166-72. PubMed ID: 22433003
    [Abstract] [Full Text] [Related]

  • 2. IL-17A and IL-17F stimulate chemokines via MAPK pathways (ERK1/2 and p38 but not JNK) in mouse cultured mesangial cells: synergy with TNF-alpha and IL-1beta.
    Iyoda M, Shibata T, Kawaguchi M, Hizawa N, Yamaoka T, Kokubu F, Akizawa T.
    Am J Physiol Renal Physiol; 2010 Mar; 298(3):F779-87. PubMed ID: 20042461
    [Abstract] [Full Text] [Related]

  • 3. The regulation of human MMP-13 by licofelone, an inhibitor of cyclo-oxygenases and 5-lipoxygenase, in human osteoarthritic chondrocytes is mediated by the inhibition of the p38 MAP kinase signalling pathway.
    Boileau C, Pelletier JP, Tardif G, Fahmi H, Laufer S, Lavigne M, Martel-Pelletier J.
    Ann Rheum Dis; 2005 Jun; 64(6):891-8. PubMed ID: 15498796
    [Abstract] [Full Text] [Related]

  • 4. Licofelone, a dual COX/5-LOX inhibitor, induces apoptosis in HCA-7 colon cancer cells through the mitochondrial pathway independently from its ability to affect the arachidonic acid cascade.
    Tavolari S, Bonafè M, Marini M, Ferreri C, Bartolini G, Brighenti E, Manara S, Tomasi V, Laufer S, Guarnieri T.
    Carcinogenesis; 2008 Feb; 29(2):371-80. PubMed ID: 18033773
    [Abstract] [Full Text] [Related]

  • 5. Licofelone, a balanced inhibitor of cyclooxygenase and 5-lipoxygenase, reduces inflammation in a rabbit model of atherosclerosis.
    Vidal C, Gómez-Hernández A, Sánchez-Galán E, González A, Ortega L, Gómez-Gerique JA, Tuñón J, Egido J.
    J Pharmacol Exp Ther; 2007 Jan; 320(1):108-16. PubMed ID: 17015640
    [Abstract] [Full Text] [Related]

  • 6. Licofelone, a novel 5-LOX/COX-inhibitor, attenuates leukocyte rolling and adhesion on endothelium under flow.
    Ulbrich H, Soehnlein O, Xie X, Eriksson EE, Lindbom L, Albrecht W, Laufer S, Dannhardt G.
    Biochem Pharmacol; 2005 Jul 01; 70(1):30-6. PubMed ID: 15894291
    [Abstract] [Full Text] [Related]

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  • 8. Study of the role of leukotriene B()4 in abnormal function of human subchondral osteoarthritis osteoblasts: effects of cyclooxygenase and/or 5-lipoxygenase inhibition.
    Paredes Y, Massicotte F, Pelletier JP, Martel-Pelletier J, Laufer S, Lajeunesse D.
    Arthritis Rheum; 2002 Jul 01; 46(7):1804-12. PubMed ID: 12124864
    [Abstract] [Full Text] [Related]

  • 9. Leptospiral membrane proteins stimulate pro-inflammatory chemokines secretion by renal tubule epithelial cells through toll-like receptor 2 and p38 mitogen activated protein kinase.
    Hung CC, Chang CT, Tian YC, Wu MS, Yu CC, Pan MJ, Vandewalle A, Yang CW.
    Nephrol Dial Transplant; 2006 Apr 01; 21(4):898-910. PubMed ID: 16339163
    [Abstract] [Full Text] [Related]

  • 10. Fractalkine increases mesangial cell proliferation through reactive oxygen species and mitogen-activated protein kinases.
    Park J, Song KH, Ha H.
    Transplant Proc; 2012 May 01; 44(4):1026-8. PubMed ID: 22564616
    [Abstract] [Full Text] [Related]

  • 11. Molecular mechanisms for the release of chemokines from human leukemic mast cell line (HMC)-1 cells activated by SCF and TNF-alpha: roles of ERK, p38 MAPK, and NF-kappaB.
    Wong CK, Tsang CM, Ip WK, Lam CW.
    Allergy; 2006 Mar 01; 61(3):289-97. PubMed ID: 16436136
    [Abstract] [Full Text] [Related]

  • 12. Differential effect of three mitogen-activated protein kinases on lipoprotein (a)-induced human mesangial cell proliferation.
    Song HM, Wei M, Xu K, Li XW.
    Chin Med J (Engl); 2010 Jan 20; 123(2):216-20. PubMed ID: 20137374
    [Abstract] [Full Text] [Related]

  • 13. Dipyridamole activation of mitogen-activated protein kinase phosphatase-1 mediates inhibition of lipopolysaccharide-induced cyclooxygenase-2 expression in RAW 264.7 cells.
    Chen TH, Kao YC, Chen BC, Chen CH, Chan P, Lee HM.
    Eur J Pharmacol; 2006 Jul 17; 541(3):138-46. PubMed ID: 16765938
    [Abstract] [Full Text] [Related]

  • 14. Rho-kinase mediates TNF-α-induced MCP-1 expression via p38 MAPK signaling pathway in mesangial cells.
    Matoba K, Kawanami D, Ishizawa S, Kanazawa Y, Yokota T, Utsunomiya K.
    Biochem Biophys Res Commun; 2010 Nov 26; 402(4):725-30. PubMed ID: 20977889
    [Abstract] [Full Text] [Related]

  • 15. Regulation of the expression of 5-lipoxygenase-activating protein/5-lipoxygenase and the synthesis of leukotriene B(4) in osteoarthritic chondrocytes: role of transforming growth factor beta and eicosanoids.
    Martel-Pelletier J, Mineau F, Fahmi H, Laufer S, Reboul P, Boileau C, Lavigne M, Pelletier JP.
    Arthritis Rheum; 2004 Dec 26; 50(12):3925-33. PubMed ID: 15593193
    [Abstract] [Full Text] [Related]

  • 16. Anticancer effects of licofelone (ML-3000) in prostate cancer cells.
    Narayanan NK, Nargi D, Attur M, Abramson SB, Narayanan BA.
    Anticancer Res; 2007 Dec 26; 27(4B):2393-402. PubMed ID: 17695530
    [Abstract] [Full Text] [Related]

  • 17. Leukotriene and prostaglandin synthesis pathways in osteoarthritic synovial membranes: regulating factors for interleukin 1beta synthesis.
    Marcouiller P, Pelletier JP, Guévremont M, Martel-Pelletier J, Ranger P, Laufer S, Reboul P.
    J Rheumatol; 2005 Apr 26; 32(4):704-12. PubMed ID: 15801029
    [Abstract] [Full Text] [Related]

  • 18. Aurothiomalate inhibits cyclooxygenase 2, matrix metalloproteinase 3, and interleukin-6 expression in chondrocytes by increasing MAPK phosphatase 1 expression and decreasing p38 phosphorylation: MAPK phosphatase 1 as a novel target for antirheumatic drugs.
    Nieminen R, Korhonen R, Moilanen T, Clark AR, Moilanen E.
    Arthritis Rheum; 2010 Jun 26; 62(6):1650-9. PubMed ID: 20178133
    [Abstract] [Full Text] [Related]

  • 19. Involvement of p38 MAP kinase in lipopolysaccharide-induced production of pro- and anti-inflammatory cytokines and prostaglandin E(2) in human choriodecidua.
    Shoji T, Yoshida S, Mitsunari M, Miyake N, Tsukihara S, Iwabe T, Harada T, Terakawa N.
    J Reprod Immunol; 2007 Oct 26; 75(2):82-90. PubMed ID: 17617469
    [Abstract] [Full Text] [Related]

  • 20. Dexamethasone reduces mitomycin C-related inflammatory cytokine expression without inducing further cell death in corneal fibroblasts.
    Chang SW, Chou SF, Yu SY.
    Wound Repair Regen; 2010 Oct 26; 18(1):59-69. PubMed ID: 20002897
    [Abstract] [Full Text] [Related]


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