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Journal Abstract Search

176 related items for PubMed ID: 22434591

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  • 3. Manipulating the expression rate and enantioselectivity of an epoxide hydrolase by using directed evolution.
    Reetz MT, Zheng H.
    Chembiochem; 2011 Jul 04; 12(10):1529-35. PubMed ID: 21567703
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  • 4. Shedding light on the efficacy of laboratory evolution based on iterative saturation mutagenesis.
    Reetz MT, Kahakeaw D, Sanchis J.
    Mol Biosyst; 2009 Feb 04; 5(2):115-22. PubMed ID: 19156255
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  • 5. Cloning of an epoxide hydrolase-encoding gene from Aspergillus niger M200, overexpression in E. coli, and modification of activity and enantioselectivity of the enzyme by protein engineering.
    Kotik M, Stepánek V, Kyslík P, Maresová H.
    J Biotechnol; 2007 Oct 15; 132(1):8-15. PubMed ID: 17875334
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  • 6. Many pathways in laboratory evolution can lead to improved enzymes: how to escape from local minima.
    Gumulya Y, Sanchis J, Reetz MT.
    Chembiochem; 2012 May 07; 13(7):1060-6. PubMed ID: 22522601
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  • 7. Enhancing the thermal robustness of an enzyme by directed evolution: least favorable starting points and inferior mutants can map superior evolutionary pathways.
    Gumulya Y, Reetz MT.
    Chembiochem; 2011 Nov 04; 12(16):2502-10. PubMed ID: 21913300
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  • 9. Laboratory evolution of an epoxide hydrolase - towards an enantioconvergent biocatalyst.
    Kotik M, Archelas A, Faměrová V, Oubrechtová P, Křen V.
    J Biotechnol; 2011 Oct 20; 156(1):1-10. PubMed ID: 21854816
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  • 10. Directed evolution of an enantioselective epoxide hydrolase: uncovering the source of enantioselectivity at each evolutionary stage.
    Reetz MT, Bocola M, Wang LW, Sanchis J, Cronin A, Arand M, Zou J, Archelas A, Bottalla AL, Naworyta A, Mowbray SL.
    J Am Chem Soc; 2009 Jun 03; 131(21):7334-43. PubMed ID: 19469578
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  • 11. Enhancing the enantioselectivity of an epoxide hydrolase by directed evolution.
    Reetz MT, Torre C, Eipper A, Lohmer R, Hermes M, Brunner B, Maichele A, Bocola M, Arand M, Cronin A, Genzel Y, Archelas A, Furstoss R.
    Org Lett; 2004 Jan 22; 6(2):177-80. PubMed ID: 14723522
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  • 12. A machine learning approach for reliable prediction of amino acid interactions and its application in the directed evolution of enantioselective enzymes.
    Cadet F, Fontaine N, Li G, Sanchis J, Ng Fuk Chong M, Pandjaitan R, Vetrivel I, Offmann B, Reetz MT.
    Sci Rep; 2018 Nov 13; 8(1):16757. PubMed ID: 30425279
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  • 14. Cloning, expression, purification, and characterization of a novel epoxide hydrolase from Aspergillus niger SQ-6.
    Liu Y, Wu S, Wang J, Yang L, Sun W.
    Protein Expr Purif; 2007 Jun 13; 53(2):239-46. PubMed ID: 17317214
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  • 15. Protein engineering of α/β-hydrolase fold enzymes.
    Jochens H, Hesseler M, Stiba K, Padhi SK, Kazlauskas RJ, Bornscheuer UT.
    Chembiochem; 2011 Jul 04; 12(10):1508-17. PubMed ID: 21506229
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  • 17. Fungal epoxide hydrolases: new landmarks in sequence-activity space.
    Smit MS.
    Trends Biotechnol; 2004 Mar 04; 22(3):123-9. PubMed ID: 15036862
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  • 18. Directed evolution of epoxide hydrolase from A. radiobacter toward higher enantioselectivity by error-prone PCR and DNA shuffling.
    van Loo B, Spelberg JH, Kingma J, Sonke T, Wubbolts MG, Janssen DB.
    Chem Biol; 2004 Jul 04; 11(7):981-90. PubMed ID: 15271356
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