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Journal Abstract Search

299 related items for PubMed ID: 22436052

  • 1. PGE(2) reverses G(s)-mediated inhibition of platelet aggregation by interaction with EP3 receptors, but adds to non-G(s)-mediated inhibition of platelet aggregation by interaction with EP4 receptors.
    Glenn JR, White AE, Iyu D, Heptinstall S.
    Platelets; 2012; 23(5):344-51. PubMed ID: 22436052
    [Abstract] [Full Text] [Related]

  • 2. PGE1 and PGE2 modify platelet function through different prostanoid receptors.
    Iyú D, Jüttner M, Glenn JR, White AE, Johnson AJ, Fox SC, Heptinstall S.
    Prostaglandins Other Lipid Mediat; 2011 Feb; 94(1-2):9-16. PubMed ID: 21095237
    [Abstract] [Full Text] [Related]

  • 3. The role of prostanoid receptors in mediating the effects of PGE(2) on human platelet function.
    Iyú D, Glenn JR, White AE, Johnson AJ, Fox SC, Heptinstall S.
    Platelets; 2010 Feb; 21(5):329-42. PubMed ID: 20433310
    [Abstract] [Full Text] [Related]

  • 4. P2Y₁₂ and EP3 antagonists promote the inhibitory effects of natural modulators of platelet aggregation that act via cAMP.
    Iyú D, Glenn JR, White AE, Fox SC, Dovlatova N, Heptinstall S.
    Platelets; 2011 Feb; 22(7):504-15. PubMed ID: 21591981
    [Abstract] [Full Text] [Related]

  • 5. Prostaglandin E2 differentially modulates human platelet function through the prostanoid EP2 and EP3 receptors.
    Petrucci G, De Cristofaro R, Rutella S, Ranelletti FO, Pocaterra D, Lancellotti S, Habib A, Patrono C, Rocca B.
    J Pharmacol Exp Ther; 2011 Feb; 336(2):391-402. PubMed ID: 21059804
    [Abstract] [Full Text] [Related]

  • 6. DG-041 inhibits the EP3 prostanoid receptor--a new target for inhibition of platelet function in atherothrombotic disease.
    Heptinstall S, Espinosa DI, Manolopoulos P, Glenn JR, White AE, Johnson A, Dovlatova N, Fox SC, May JA, Hermann D, Magnusson O, Stefansson K, Hartman D, Gurney M.
    Platelets; 2008 Dec; 19(8):605-13. PubMed ID: 19012178
    [Abstract] [Full Text] [Related]

  • 7. Mode of action of P2Y(12 ) antagonists as inhibitors of platelet function.
    Iyú D, Glenn JR, White AE, Fox SC, van Giezen H, Nylander S, Heptinstall S.
    Thromb Haemost; 2011 Jan; 105(1):96-106. PubMed ID: 20941457
    [Abstract] [Full Text] [Related]

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  • 9. Prostaglandin E2 levels and platelet function are different in cord blood compared to adults.
    Schlagenhauf A, Haidl H, Leschnik B, Leis HJ, Heinemann A, Muntean W.
    Thromb Haemost; 2015 Jan; 113(1):97-106. PubMed ID: 25118631
    [Abstract] [Full Text] [Related]

  • 10. The prostaglandin E2 receptor EP4 is expressed by human platelets and potently inhibits platelet aggregation and thrombus formation.
    Philipose S, Konya V, Sreckovic I, Marsche G, Lippe IT, Peskar BA, Heinemann A, Schuligoi R.
    Arterioscler Thromb Vasc Biol; 2010 Dec; 30(12):2416-23. PubMed ID: 21071691
    [Abstract] [Full Text] [Related]

  • 11. The role of PGE(2) in human atherosclerotic plaque on platelet EP(3) and EP(4) receptor activation and platelet function in whole blood.
    Schober LJ, Khandoga AL, Dwivedi S, Penz SM, Maruyama T, Brandl R, Siess W.
    J Thromb Thrombolysis; 2011 Aug; 32(2):158-66. PubMed ID: 21424266
    [Abstract] [Full Text] [Related]

  • 12. Blocking the EP3 receptor for PGE2 with DG-041 decreases thrombosis without impairing haemostatic competence.
    Tilly P, Charles AL, Ludwig S, Slimani F, Gross S, Meilhac O, Geny B, Stefansson K, Gurney ME, Fabre JE.
    Cardiovasc Res; 2014 Mar 01; 101(3):482-91. PubMed ID: 24323317
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  • 14. Potentiation of aggregation and inhibition of adenylate cyclase in human platelets by prostaglandin E analogues.
    Matthews JS, Jones RL.
    Br J Pharmacol; 1993 Feb 01; 108(2):363-9. PubMed ID: 8448586
    [Abstract] [Full Text] [Related]

  • 15. Effects on platelet function of an EP3 receptor antagonist used alone and in combination with a P2Y12 antagonist both in-vitro and ex-vivo in human volunteers.
    Fox SC, May JA, Johnson A, Hermann D, Strieter D, Hartman D, Heptinstall S.
    Platelets; 2013 Feb 01; 24(5):392-400. PubMed ID: 22866894
    [Abstract] [Full Text] [Related]

  • 16. The activity of constitutive nitric oxide synthase is increased by the pathway cAMP/cAMP-activated protein kinase in human platelets. New insights into the antiaggregating effects of cAMP-elevating agents.
    Russo I, Doronzo G, Mattiello L, De Salve A, Trovati M, Anfossi G.
    Thromb Res; 2004 Feb 01; 114(4):265-73. PubMed ID: 15381390
    [Abstract] [Full Text] [Related]

  • 17. A noble function of BAY 11-7082: Inhibition of platelet aggregation mediated by an elevated cAMP-induced VASP, and decreased ERK2/JNK1 phosphorylations.
    Lee HS, Kim SD, Lee WM, Endale M, Kamruzzaman SM, Oh WJ, Cho JY, Kim SK, Cho HJ, Park HJ, Rhee MH.
    Eur J Pharmacol; 2010 Feb 10; 627(1-3):85-91. PubMed ID: 19913011
    [Abstract] [Full Text] [Related]

  • 18. Detection of P2Y(14) protein in platelets and investigation of the role of P2Y(14) in platelet function in comparison with the EP(3) receptor.
    Dovlatova N, Wijeyeratne YD, Fox SC, Manolopoulos P, Johnson AJ, White AE, Latif ML, Ralevic V, Heptinstall S.
    Thromb Haemost; 2008 Aug 10; 100(2):261-70. PubMed ID: 18690346
    [Abstract] [Full Text] [Related]

  • 19. Reciprocal regulation of human platelet function by endogenous prostanoids and through multiple prostanoid receptors.
    Hubertus K, Mischnik M, Timmer J, Herterich S, Mark R, Moulard M, Walter U, Geiger J.
    Eur J Pharmacol; 2014 Oct 05; 740():15-27. PubMed ID: 25003953
    [Abstract] [Full Text] [Related]

  • 20. Differential regulation of airway smooth muscle cell migration by E-prostanoid receptor subtypes.
    Aso H, Ito S, Mori A, Suganuma N, Morioka M, Takahara N, Kondo M, Hasegawa Y.
    Am J Respir Cell Mol Biol; 2013 Mar 05; 48(3):322-9. PubMed ID: 23221043
    [Abstract] [Full Text] [Related]

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