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553 related items for PubMed ID: 22437842

  • 1. Reactivation kinetics of a homologous series of bispyridinium bis-oximes with nerve agent-inhibited human acetylcholinesterase.
    Worek F, von der Wellen J, Musilek K, Kuca K, Thiermann H.
    Arch Toxicol; 2012 Sep; 86(9):1379-86. PubMed ID: 22437842
    [Abstract] [Full Text] [Related]

  • 2. Structural requirements for effective oximes--evaluation of kinetic in vitro data with phosphylated human AChE and structurally different oximes.
    Worek F, Wille T, Koller M, Thiermann H.
    Chem Biol Interact; 2013 Mar 25; 203(1):125-8. PubMed ID: 22827894
    [Abstract] [Full Text] [Related]

  • 3. Kinetic analysis of interactions of different sarin and tabun analogues with human acetylcholinesterase and oximes: is there a structure-activity relationship?
    Aurbek N, Herkert NM, Koller M, Thiermann H, Worek F.
    Chem Biol Interact; 2010 Sep 06; 187(1-3):215-9. PubMed ID: 20105433
    [Abstract] [Full Text] [Related]

  • 4. Investigation of the reactivation kinetics of a large series of bispyridinium oximes with organophosphate-inhibited human acetylcholinesterase.
    Winter M, Wille T, Musilek K, Kuca K, Thiermann H, Worek F.
    Toxicol Lett; 2016 Feb 26; 244():136-142. PubMed ID: 26210933
    [Abstract] [Full Text] [Related]

  • 5. In vitro reactivation of sarin-inhibited human acetylcholinesterase (AChE) by bis-pyridinium oximes connected by xylene linkers.
    Acharya J, Dubey DK, Srivastava AK, Raza SK.
    Toxicol In Vitro; 2011 Feb 26; 25(1):251-6. PubMed ID: 20688148
    [Abstract] [Full Text] [Related]

  • 6. A common mechanism for resistance to oxime reactivation of acetylcholinesterase inhibited by organophosphorus compounds.
    Maxwell DM, Brecht KM, Sweeney RE.
    Chem Biol Interact; 2013 Mar 25; 203(1):72-6. PubMed ID: 22982773
    [Abstract] [Full Text] [Related]

  • 7. Enzyme-kinetic investigation of different sarin analogues reacting with human acetylcholinesterase and butyrylcholinesterase.
    Bartling A, Worek F, Szinicz L, Thiermann H.
    Toxicology; 2007 Apr 20; 233(1-3):166-72. PubMed ID: 16904809
    [Abstract] [Full Text] [Related]

  • 8. A comparison of the efficacy of a bispyridinium oxime--1,4-bis-(2-hydroxyiminomethylpyridinium) butane dibromide and currently used oximes to reactivate sarin, tabun or cyclosarin-inhibited acetylcholinesterase by in vitro methods.
    Kuca K, Cabal J, Kassa J.
    Pharmazie; 2004 Oct 20; 59(10):795-8. PubMed ID: 15544060
    [Abstract] [Full Text] [Related]

  • 9. Interaction of pentylsarin analogues with human acetylcholinesterase: a kinetic study.
    Worek F, Herkert NM, Koller M, Aurbek N, Thiermann H.
    Toxicol Lett; 2009 Jun 01; 187(2):119-23. PubMed ID: 19429253
    [Abstract] [Full Text] [Related]

  • 10. Interactions between xylene-linked carbamoyl bis-pyridinium mono-oximes and organophosphates inhibited-AChE: a kinetic study.
    Sharma R, Gupta B, Acharya J, Kaushik MP, Ghosh KK.
    Toxicology; 2014 Feb 28; 316():1-8. PubMed ID: 24345352
    [Abstract] [Full Text] [Related]

  • 11. Novel series of bispyridinium compounds bearing a (Z)-but-2-ene linker--synthesis and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase.
    Musilek K, Holas O, Kuca K, Jun D, Dohnal V, Opletalova V, Dolezal M.
    Bioorg Med Chem Lett; 2007 Jun 01; 17(11):3172-6. PubMed ID: 17383875
    [Abstract] [Full Text] [Related]

  • 12. Effect of reversible ligands on oxime-induced reactivation of sarin- and cyclosarin-inhibited human acetylcholinesterase.
    Scheffel C, Thiermann H, Worek F.
    Toxicol Lett; 2015 Feb 03; 232(3):557-65. PubMed ID: 25522658
    [Abstract] [Full Text] [Related]

  • 13. Kinetic analysis of interactions between alkylene-linked bis-pyridiniumaldoximes and human acetylcholinesterases inhibited by various organophosphorus compounds.
    Wille T, Ekström F, Lee JC, Pang YP, Thiermann H, Worek F.
    Biochem Pharmacol; 2010 Sep 15; 80(6):941-6. PubMed ID: 20510679
    [Abstract] [Full Text] [Related]

  • 14. Reactivation of organophosphate-inhibited human AChE by combinations of obidoxime and HI 6 in vitro.
    Worek F, Aurbek N, Thiermann H.
    J Appl Toxicol; 2007 Sep 15; 27(6):582-8. PubMed ID: 17370251
    [Abstract] [Full Text] [Related]

  • 15. Kinetic interactions of a homologous series of bispyridinium monooximes (HGG oximes) with native and phosphonylated human acetylcholinesterase.
    Worek F, Bierwisch A, Wille T, Koller M, Thiermann H.
    Toxicol Lett; 2012 Jul 07; 212(1):29-32. PubMed ID: 22561105
    [Abstract] [Full Text] [Related]

  • 16. Reactivation kinetics of a series of related bispyridinium oximes with organophosphate-inhibited human acetylcholinesterase--Structure-activity relationships.
    Worek F, Wille T, Koller M, Thiermann H.
    Biochem Pharmacol; 2012 Jun 15; 83(12):1700-6. PubMed ID: 22649796
    [Abstract] [Full Text] [Related]

  • 17. Oxime-mediated in vitro reactivation kinetic analysis of organophosphates-inhibited human and electric eel acetylcholinesterase.
    Sahu AK, Sharma R, Gupta B, Musilek K, Kuca K, Acharya J, Ghosh KK.
    Toxicol Mech Methods; 2016 Jun 15; 26(5):319-26. PubMed ID: 27101948
    [Abstract] [Full Text] [Related]

  • 18. In vitro reactivation kinetics of paraoxon- and DFP-inhibited electric eel AChE using mono- and bis-pyridinium oximes.
    Gupta B, Sharma R, Singh N, Kuca K, Acharya JR, Ghosh KK.
    Arch Toxicol; 2014 Feb 15; 88(2):381-90. PubMed ID: 24065055
    [Abstract] [Full Text] [Related]

  • 19. Reactivation of organophosphate-inhibited human acetylcholinesterase by isonitrosoacetone (MINA): a kinetic analysis.
    Worek F, Thiermann H.
    Chem Biol Interact; 2011 Nov 15; 194(2-3):91-6. PubMed ID: 21930118
    [Abstract] [Full Text] [Related]

  • 20. Exploring the physicochemical properties of oxime-reactivation therapeutics for cyclosarin, sarin, tabun, and VX inactivated acetylcholinesterase.
    Esposito EX, Stouch TR, Wymore T, Madura JD.
    Chem Res Toxicol; 2014 Jan 21; 27(1):99-110. PubMed ID: 24443939
    [Abstract] [Full Text] [Related]

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