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Journal Abstract Search

188 related items for PubMed ID: 22441987

  • 1. Loss of giant obscurins promotes breast epithelial cell survival through apoptotic resistance.
    Perry NA, Shriver M, Mameza MG, Grabias B, Balzer E, Kontrogianni-Konstantopoulos A.
    FASEB J; 2012 Jul; 26(7):2764-75. PubMed ID: 22441987
    [Abstract] [Full Text] [Related]

  • 2. Loss of giant obscurins from breast epithelium promotes epithelial-to-mesenchymal transition, tumorigenicity and metastasis.
    Shriver M, Stroka KM, Vitolo MI, Martin S, Huso DL, Konstantopoulos K, Kontrogianni-Konstantopoulos A.
    Oncogene; 2015 Aug 06; 34(32):4248-59. PubMed ID: 25381817
    [Abstract] [Full Text] [Related]

  • 3. Obscurins: Goliaths and Davids take over non-muscle tissues.
    Ackermann MA, Shriver M, Perry NA, Hu LY, Kontrogianni-Konstantopoulos A.
    PLoS One; 2014 Aug 06; 9(2):e88162. PubMed ID: 24516603
    [Abstract] [Full Text] [Related]

  • 4. Giant obscurins regulate the PI3K cascade in breast epithelial cells via direct binding to the PI3K/p85 regulatory subunit.
    Shriver M, Marimuthu S, Paul C, Geist J, Seale T, Konstantopoulos K, Kontrogianni-Konstantopoulos A.
    Oncotarget; 2016 Jul 19; 7(29):45414-45428. PubMed ID: 27323778
    [Abstract] [Full Text] [Related]

  • 5. Obscurin: A multitasking giant in the fight against cancer.
    Guardia T, Eason M, Kontrogianni-Konstantopoulos A.
    Biochim Biophys Acta Rev Cancer; 2021 Aug 19; 1876(1):188567. PubMed ID: 34015411
    [Abstract] [Full Text] [Related]

  • 6. Giant obscurin regulates migration and metastasis via RhoA-dependent cytoskeletal remodeling in pancreatic cancer.
    Tuntithavornwat S, Shea DJ, Wong BS, Guardia T, Lee SJ, Yankaskas CL, Zheng L, Kontrogianni-Konstantopoulos A, Konstantopoulos K.
    Cancer Lett; 2022 Feb 01; 526():155-167. PubMed ID: 34826548
    [Abstract] [Full Text] [Related]

  • 7. Obscurins: unassuming giants enter the spotlight.
    Perry NA, Ackermann MA, Shriver M, Hu LY, Kontrogianni-Konstantopoulos A.
    IUBMB Life; 2013 Jun 01; 65(6):479-86. PubMed ID: 23512348
    [Abstract] [Full Text] [Related]

  • 8. Loss of the obscurin-RhoGEF downregulates RhoA signaling and increases microtentacle formation and attachment of breast epithelial cells.
    Perry NA, Vitolo MI, Martin SS, Kontrogianni-Konstantopoulos A.
    Oncotarget; 2014 Sep 30; 5(18):8558-68. PubMed ID: 25261370
    [Abstract] [Full Text] [Related]

  • 9. Differential expression of WISP-1 and WISP-2 genes in normal and transformed human breast cell lines.
    Saxena N, Banerjee S, Sengupta K, Zoubine MN, Banerjee SK.
    Mol Cell Biochem; 2001 Dec 30; 228(1-2):99-104. PubMed ID: 11855747
    [Abstract] [Full Text] [Related]

  • 10. Deregulated Ca2+ cycling underlies the development of arrhythmia and heart disease due to mutant obscurin.
    Hu LR, Ackermann MA, Hecker PA, Prosser BL, King B, O'Connell KA, Grogan A, Meyer LC, Berndsen CE, Wright NT, Jonathan Lederer W, Kontrogianni-Konstantopoulos A.
    Sci Adv; 2017 Jun 30; 3(6):e1603081. PubMed ID: 28630914
    [Abstract] [Full Text] [Related]

  • 11. KLF5 promotes breast cell survival partially through fibroblast growth factor-binding protein 1-pERK-mediated dual specificity MKP-1 protein phosphorylation and stabilization.
    Liu R, Zheng HQ, Zhou Z, Dong JT, Chen C.
    J Biol Chem; 2009 Jun 19; 284(25):16791-16798. PubMed ID: 19411256
    [Abstract] [Full Text] [Related]

  • 12. Passive stiffness changes caused by upregulation of compliant titin isoforms in human dilated cardiomyopathy hearts.
    Makarenko I, Opitz CA, Leake MC, Neagoe C, Kulke M, Gwathmey JK, del Monte F, Hajjar RJ, Linke WA.
    Circ Res; 2004 Oct 01; 95(7):708-16. PubMed ID: 15345656
    [Abstract] [Full Text] [Related]

  • 13. AKT-1, -2, and -3 are expressed in both normal and tumor tissues of the lung, breast, prostate, and colon.
    Zinda MJ, Johnson MA, Paul JD, Horn C, Konicek BW, Lu ZH, Sandusky G, Thomas JE, Neubauer BL, Lai MT, Graff JR.
    Clin Cancer Res; 2001 Aug 01; 7(8):2475-9. PubMed ID: 11489829
    [Abstract] [Full Text] [Related]

  • 14. Unraveling obscurins in heart disease.
    Grogan A, Kontrogianni-Konstantopoulos A.
    Pflugers Arch; 2019 May 01; 471(5):735-743. PubMed ID: 30099631
    [Abstract] [Full Text] [Related]

  • 15. OBSCN restoration via OBSCN-AS1 long-noncoding RNA CRISPR-targeting suppresses metastasis in triple-negative breast cancer.
    Guardia T, Zhang Y, Thompson KN, Lee SJ, Martin SS, Konstantopoulos K, Kontrogianni-Konstantopoulos A.
    Proc Natl Acad Sci U S A; 2023 Mar 14; 120(11):e2215553120. PubMed ID: 36877839
    [Abstract] [Full Text] [Related]

  • 16. The ETS transcription factor ESE-1 transforms MCF-12A human mammary epithelial cells via a novel cytoplasmic mechanism.
    Prescott JD, Koto KS, Singh M, Gutierrez-Hartmann A.
    Mol Cell Biol; 2004 Jun 14; 24(12):5548-64. PubMed ID: 15169914
    [Abstract] [Full Text] [Related]

  • 17. The kinase domains of obscurin interact with intercellular adhesion proteins.
    Hu LY, Kontrogianni-Konstantopoulos A.
    FASEB J; 2013 May 14; 27(5):2001-12. PubMed ID: 23392350
    [Abstract] [Full Text] [Related]

  • 18. Rapid response of cardiac obscurin gene cluster to aortic stenosis: differential activation of Rho-GEF and MLCK and involvement in hypertrophic growth.
    Borisov AB, Raeker MO, Kontrogianni-Konstantopoulos A, Yang K, Kurnit DM, Bloch RJ, Russell MW.
    Biochem Biophys Res Commun; 2003 Oct 24; 310(3):910-8. PubMed ID: 14550291
    [Abstract] [Full Text] [Related]

  • 19. Loss of giant obscurins alters breast epithelial cell mechanosensing of matrix stiffness.
    Stroka KM, Wong BS, Shriver M, Phillip JM, Wirtz D, Kontrogianni-Konstantopoulos A, Konstantopoulos K.
    Oncotarget; 2017 Aug 15; 8(33):54004-54020. PubMed ID: 28903319
    [Abstract] [Full Text] [Related]

  • 20. The nuclear guanine nucleotide exchange factors Ect2 and Net1 regulate RhoB-mediated cell death after DNA damage.
    Srougi MC, Burridge K.
    PLoS One; 2011 Feb 23; 6(2):e17108. PubMed ID: 21373644
    [Abstract] [Full Text] [Related]

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