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228 related items for PubMed ID: 22451662

  • 1. Reduction of Na/K-ATPase potentiates marinobufagenin-induced cardiac dysfunction and myocyte apoptosis.
    Liu C, Bai Y, Chen Y, Wang Y, Sottejeau Y, Liu L, Li X, Lingrel JB, Malhotra D, Cooper CJ, Shapiro JI, Xie ZJ, Tian J.
    J Biol Chem; 2012 May 11; 287(20):16390-8. PubMed ID: 22451662
    [Abstract] [Full Text] [Related]

  • 2. Association of PI3K-Akt signaling pathway with digitalis-induced hypertrophy of cardiac myocytes.
    Liu L, Zhao X, Pierre SV, Askari A.
    Am J Physiol Cell Physiol; 2007 Nov 11; 293(5):C1489-97. PubMed ID: 17728397
    [Abstract] [Full Text] [Related]

  • 3. Marinobufagenin enhances cardiac contractility in mice with ouabain-sensitive alpha1 Na+-K+-ATPase.
    Wansapura AN, Lasko V, Xie Z, Fedorova OV, Bagrov AY, Lingrel JB, Lorenz JN.
    Am J Physiol Heart Circ Physiol; 2009 Jun 11; 296(6):H1833-9. PubMed ID: 19376809
    [Abstract] [Full Text] [Related]

  • 4. Reduction of Na/K-ATPase affects cardiac remodeling and increases c-kit cell abundance in partial nephrectomized mice.
    Drummond CA, Sayed M, Evans KL, Shi H, Wang X, Haller ST, Liu J, Cooper CJ, Xie Z, Shapiro JI, Tian J.
    Am J Physiol Heart Circ Physiol; 2014 Jun 15; 306(12):H1631-43. PubMed ID: 24748592
    [Abstract] [Full Text] [Related]

  • 5. Rapamycin Attenuates Cardiac Fibrosis in Experimental Uremic Cardiomyopathy by Reducing Marinobufagenin Levels and Inhibiting Downstream Pro-Fibrotic Signaling.
    Haller ST, Yan Y, Drummond CA, Xie J, Tian J, Kennedy DJ, Shilova VY, Xie Z, Liu J, Cooper CJ, Malhotra D, Shapiro JI, Fedorova OV, Bagrov AY.
    J Am Heart Assoc; 2016 Sep 30; 5(10):. PubMed ID: 27694325
    [Abstract] [Full Text] [Related]

  • 6. Na+/K+-ATPase inhibition by ouabain induces CaMKII-dependent apoptosis in adult rat cardiac myocytes.
    Sapia L, Palomeque J, Mattiazzi A, Petroff MV.
    J Mol Cell Cardiol; 2010 Sep 30; 49(3):459-68. PubMed ID: 20435043
    [Abstract] [Full Text] [Related]

  • 7. The involvement of Akt, mTOR, and S6K in the in vivo effect of IGF-1 on the regulation of rat cardiac Na+/K+-ATPase.
    Banjac K, Obradovic M, Zafirovic S, Essack M, Gluvic Z, Sunderic M, Nedic O, Isenovic ER.
    Mol Biol Rep; 2024 Apr 15; 51(1):517. PubMed ID: 38622478
    [Abstract] [Full Text] [Related]

  • 8. Changes in sodium pump expression dictate the effects of ouabain on cell growth.
    Tian J, Li X, Liang M, Liu L, Xie JX, Ye Q, Kometiani P, Tillekeratne M, Jin R, Xie Z.
    J Biol Chem; 2009 May 29; 284(22):14921-9. PubMed ID: 19329430
    [Abstract] [Full Text] [Related]

  • 9. Myocardial PKC beta2 and the sensitivity of Na/K-ATPase to marinobufagenin are reduced by cicletanine in Dahl hypertension.
    Fedorova OV, Talan MI, Agalakova NI, Droy-Lefaix MT, Lakatta EG, Bagrov AY.
    Hypertension; 2003 Mar 29; 41(3):505-11. PubMed ID: 12623951
    [Abstract] [Full Text] [Related]

  • 10. Na(+)/K)+)-ATPase α2-isoform preferentially modulates Ca2(+) transients and sarcoplasmic reticulum Ca2(+) release in cardiac myocytes.
    Despa S, Lingrel JB, Bers DM.
    Cardiovasc Res; 2012 Sep 01; 95(4):480-6. PubMed ID: 22739122
    [Abstract] [Full Text] [Related]

  • 11. Na/K-ATPase signaling mediates miR-29b-3p regulation and cardiac fibrosis formation in mice with chronic kidney disease.
    Drummond CA, Fan X, Haller ST, Kennedy DJ, Liu J, Tian J.
    PLoS One; 2018 Sep 01; 13(5):e0197688. PubMed ID: 29775473
    [Abstract] [Full Text] [Related]

  • 12. Cicletanine reverses vasoconstriction induced by the endogenous sodium pump ligand, marinobufagenin, via a protein kinase C dependent mechanism.
    Bagrov AY, Dmitrieva RI, Dorofeeva NA, Fedorova OV, Lopatin DA, Lakatta EG, Droy-Lefaix MT.
    J Hypertens; 2000 Feb 01; 18(2):209-15. PubMed ID: 10694190
    [Abstract] [Full Text] [Related]

  • 13. Examination of the cellular mechanisms by which marinobufagenin inhibits cytotrophoblast function.
    Uddin MN, Horvat D, Glaser SS, Mitchell BM, Puschett JB.
    J Biol Chem; 2008 Jun 27; 283(26):17946-53. PubMed ID: 18434301
    [Abstract] [Full Text] [Related]

  • 14. Expression of rat Na-K-ATPase α2 enables ion pumping but not ouabain-induced signaling in α1-deficient porcine renal epithelial cells.
    Xie J, Ye Q, Cui X, Madan N, Yi Q, Pierre SV, Xie Z.
    Am J Physiol Cell Physiol; 2015 Sep 15; 309(6):C373-82. PubMed ID: 26108663
    [Abstract] [Full Text] [Related]

  • 15. Identification of a mutant α1 Na/K-ATPase that pumps but is defective in signal transduction.
    Lai F, Madan N, Ye Q, Duan Q, Li Z, Wang S, Si S, Xie Z.
    J Biol Chem; 2013 May 10; 288(19):13295-304. PubMed ID: 23532853
    [Abstract] [Full Text] [Related]

  • 16. New bufadienolides extracted from Rhinella marina inhibit Na,K-ATPase and induce apoptosis by activating caspases 3 and 9 in human breast and ovarian cancer cells.
    Garcia IJP, de Oliveira GC, de Moura Valadares JM, Banfi FF, Andrade SN, Freitas TR, Dos Santos Monção Filho E, Lima Santos H, Júnior GMV, Chaves MH, de Jesus Rodrigues D, Sanchez BAM, Varotti FP, Barbosa LA.
    Steroids; 2019 Dec 10; 152():108490. PubMed ID: 31499071
    [Abstract] [Full Text] [Related]

  • 17. Effects of cardiac glycosides on sodium pump expression and function in LLC-PK1 and MDCK cells.
    Liu J, Periyasamy SM, Gunning W, Fedorova OV, Bagrov AY, Malhotra D, Xie Z, Shapiro JI.
    Kidney Int; 2002 Dec 10; 62(6):2118-25. PubMed ID: 12427136
    [Abstract] [Full Text] [Related]

  • 18. Regulation of cardiac myocyte contractility by phospholemman: Na+/Ca2+ exchange versus Na+ -K+ -ATPase.
    Song J, Zhang XQ, Wang J, Cheskis E, Chan TO, Feldman AM, Tucker AL, Cheung JY.
    Am J Physiol Heart Circ Physiol; 2008 Oct 10; 295(4):H1615-25. PubMed ID: 18708446
    [Abstract] [Full Text] [Related]

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