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564 related items for PubMed ID: 22453599

  • 1. Carnosic acid modulates Akt/IKK/NF-κB signaling by PP2A and induces intrinsic and extrinsic pathway mediated apoptosis in human prostate carcinoma PC-3 cells.
    Kar S, Palit S, Ball WB, Das PK.
    Apoptosis; 2012 Jul; 17(7):735-47. PubMed ID: 22453599
    [Abstract] [Full Text] [Related]

  • 2. Zoledronic acid in combination with serine/threonine phosphatase inhibitors induces enhanced cytotoxicity and apoptosis in hormone-refractory prostate cancer cell lines by decreasing the activities of PP1 and PP2A.
    Cirak Y, Varol U, Atmaca H, Kisim A, Sezgin C, Karabulut B, Uzunoglu S, Uslu R, Karaca B.
    BJU Int; 2012 Dec; 110(11 Pt C):E1147-54. PubMed ID: 22882676
    [Abstract] [Full Text] [Related]

  • 3. Induction of Pi form of glutathione S-transferase by carnosic acid is mediated through PI3K/Akt/NF-κB pathway and protects against neurotoxicity.
    Lin CY, Chen JH, Fu RH, Tsai CW.
    Chem Res Toxicol; 2014 Nov 17; 27(11):1958-66. PubMed ID: 25271104
    [Abstract] [Full Text] [Related]

  • 4. Expression of NF-κB-related proteins and their modulation during TNF-α-provoked apoptosis in prostate cancer cells.
    Rodríguez-Berriguete G, Fraile B, Paniagua R, Aller P, Royuela M.
    Prostate; 2012 Jan 17; 72(1):40-50. PubMed ID: 21520161
    [Abstract] [Full Text] [Related]

  • 5. Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBalpha kinase and Akt activation.
    Aggarwal S, Ichikawa H, Takada Y, Sandur SK, Shishodia S, Aggarwal BB.
    Mol Pharmacol; 2006 Jan 17; 69(1):195-206. PubMed ID: 16219905
    [Abstract] [Full Text] [Related]

  • 6. Activation of PI3K/Akt/IKK-alpha/NF-kappaB signaling pathway is required for the apoptosis-evasion in human salivary adenoid cystic carcinoma: its inhibition by quercetin.
    Sun ZJ, Chen G, Hu X, Zhang W, Liu Y, Zhu LX, Zhou Q, Zhao YF.
    Apoptosis; 2010 Jul 17; 15(7):850-63. PubMed ID: 20386985
    [Abstract] [Full Text] [Related]

  • 7. Apoptosis induced by protein phosphatase 2A (PP2A) inhibition in T leukemia cells is negatively regulated by PP2A-associated p38 mitogen-activated protein kinase.
    Boudreau RT, Conrad DM, Hoskin DW.
    Cell Signal; 2007 Jan 17; 19(1):139-51. PubMed ID: 16844342
    [Abstract] [Full Text] [Related]

  • 8. Inhibition of nuclear factor kappaB activation in PC3 cells by genistein is mediated via Akt signaling pathway.
    Li Y, Sarkar FH.
    Clin Cancer Res; 2002 Jul 17; 8(7):2369-77. PubMed ID: 12114442
    [Abstract] [Full Text] [Related]

  • 9. Effects of IKK inhibitor PS1145 on NF-kappaB function, proliferation, apoptosis and invasion activity in prostate carcinoma cells.
    Yemelyanov A, Gasparian A, Lindholm P, Dang L, Pierce JW, Kisseljov F, Karseladze A, Budunova I.
    Oncogene; 2006 Jan 19; 25(3):387-98. PubMed ID: 16170348
    [Abstract] [Full Text] [Related]

  • 10. Genetic deletion of PKR abrogates TNF-induced activation of IkappaBalpha kinase, JNK, Akt and cell proliferation but potentiates p44/p42 MAPK and p38 MAPK activation.
    Takada Y, Ichikawa H, Pataer A, Swisher S, Aggarwal BB.
    Oncogene; 2007 Feb 22; 26(8):1201-12. PubMed ID: 16924232
    [Abstract] [Full Text] [Related]

  • 11. Embelin inhibits growth and induces apoptosis through the suppression of Akt/mTOR/S6K1 signaling cascades.
    Kim SW, Kim SM, Bae H, Nam D, Lee JH, Lee SG, Shim BS, Kim SH, Ahn KS, Choi SH, Sethi G, Ahn KS.
    Prostate; 2013 Feb 15; 73(3):296-305. PubMed ID: 22887478
    [Abstract] [Full Text] [Related]

  • 12. Androgen blocks apoptosis of hormone-dependent prostate cancer cells.
    Kimura K, Markowski M, Bowen C, Gelmann EP.
    Cancer Res; 2001 Jul 15; 61(14):5611-8. PubMed ID: 11454715
    [Abstract] [Full Text] [Related]

  • 13. Acacetin (5,7-dihydroxy-4'-methoxyflavone) exhibits in vitro and in vivo anticancer activity through the suppression of NF-κB/Akt signaling in prostate cancer cells.
    Kim HR, Park CG, Jung JY.
    Int J Mol Med; 2014 Feb 15; 33(2):317-24. PubMed ID: 24285354
    [Abstract] [Full Text] [Related]

  • 14. An antitumor peptide from Musca domestica pupae (MATP) induces apoptosis in HepG2 cells through a JNK-mediated and Akt-mediated NF-κB pathway.
    Zhang R, Cao X, Wang C, Hou L, Nie J, Zhou M, Feng Y.
    Anticancer Drugs; 2012 Sep 15; 23(8):827-35. PubMed ID: 22824823
    [Abstract] [Full Text] [Related]

  • 15. PP2A inhibitors induce apoptosis in pancreatic cancer cell line PANC-1 through persistent phosphorylation of IKKα and sustained activation of the NF-κB pathway.
    Li W, Chen Z, Zong Y, Gong F, Zhu Y, Zhu Y, Lv J, Zhang J, Xie L, Sun Y, Miao Y, Tao M, Han X, Xu Z.
    Cancer Lett; 2011 May 28; 304(2):117-27. PubMed ID: 21376459
    [Abstract] [Full Text] [Related]

  • 16. Id-1 expression promotes cell survival through activation of NF-kappaB signalling pathway in prostate cancer cells.
    Ling MT, Wang X, Ouyang XS, Xu K, Tsao SW, Wong YC.
    Oncogene; 2003 Jul 17; 22(29):4498-508. PubMed ID: 12881706
    [Abstract] [Full Text] [Related]

  • 17. Human urine extract CDA-2 induces apoptosis of myelodysplastic syndrome-derived MUTZ-1 cells through the PI3K/Akt signaling pathway in a caspase-3-dependent manner.
    Huang J, Yang M, Liu H, Jin J.
    Acta Pharmacol Sin; 2008 Aug 17; 29(8):951-64. PubMed ID: 18664328
    [Abstract] [Full Text] [Related]

  • 18. Magnolol suppresses NF-kappaB activation and NF-kappaB regulated gene expression through inhibition of IkappaB kinase activation.
    Tse AK, Wan CK, Zhu GY, Shen XL, Cheung HY, Yang M, Fong WF.
    Mol Immunol; 2007 Apr 17; 44(10):2647-58. PubMed ID: 17240450
    [Abstract] [Full Text] [Related]

  • 19. A novel polysaccharide, isolated from Angelica sinensis (Oliv.) Diels induces the apoptosis of cervical cancer HeLa cells through an intrinsic apoptotic pathway.
    Cao W, Li XQ, Wang X, Fan HT, Zhang XN, Hou Y, Liu SB, Mei QB.
    Phytomedicine; 2010 Jul 17; 17(8-9):598-605. PubMed ID: 20092988
    [Abstract] [Full Text] [Related]

  • 20. SH-5, an AKT inhibitor potentiates apoptosis and inhibits invasion through the suppression of anti-apoptotic, proliferative and metastatic gene products regulated by IkappaBalpha kinase activation.
    Sethi G, Ahn KS, Sung B, Kunnumakkara AB, Chaturvedi MM, Aggarwal BB.
    Biochem Pharmacol; 2008 Dec 01; 76(11):1404-16. PubMed ID: 18606397
    [Abstract] [Full Text] [Related]

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