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269 related items for PubMed ID: 22454523

  • 1. Botulinum neurotoxin D-C uses synaptotagmin I and II as receptors, and human synaptotagmin II is not an effective receptor for type B, D-C and G toxins.
    Peng L, Berntsson RP, Tepp WH, Pitkin RM, Johnson EA, Stenmark P, Dong M.
    J Cell Sci; 2012 Jul 01; 125(Pt 13):3233-42. PubMed ID: 22454523
    [Abstract] [Full Text] [Related]

  • 2. Mechanism of botulinum neurotoxin B and G entry into hippocampal neurons.
    Dong M, Tepp WH, Liu H, Johnson EA, Chapman ER.
    J Cell Biol; 2007 Dec 31; 179(7):1511-22. PubMed ID: 18158333
    [Abstract] [Full Text] [Related]

  • 3. Structural basis of cell surface receptor recognition by botulinum neurotoxin B.
    Chai Q, Arndt JW, Dong M, Tepp WH, Johnson EA, Chapman ER, Stevens RC.
    Nature; 2006 Dec 21; 444(7122):1096-100. PubMed ID: 17167418
    [Abstract] [Full Text] [Related]

  • 4. Botulinum neurotoxin B recognizes its protein receptor with high affinity and specificity.
    Jin R, Rummel A, Binz T, Brunger AT.
    Nature; 2006 Dec 21; 444(7122):1092-5. PubMed ID: 17167421
    [Abstract] [Full Text] [Related]

  • 5. Botulinum neurotoxin G binds synaptotagmin-II in a mode similar to that of serotype B: tyrosine 1186 and lysine 1191 cause its lower affinity.
    Willjes G, Mahrhold S, Strotmeier J, Eichner T, Rummel A, Binz T.
    Biochemistry; 2013 Jun 04; 52(22):3930-8. PubMed ID: 23647335
    [Abstract] [Full Text] [Related]

  • 6. Identification of the protein receptor binding site of botulinum neurotoxins B and G proves the double-receptor concept.
    Rummel A, Eichner T, Weil T, Karnath T, Gutcaits A, Mahrhold S, Sandhoff K, Proia RL, Acharya KR, Bigalke H, Binz T.
    Proc Natl Acad Sci U S A; 2007 Jan 02; 104(1):359-64. PubMed ID: 17185412
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  • 7. Double receptor anchorage of botulinum neurotoxins accounts for their exquisite neurospecificity.
    Rummel A.
    Curr Top Microbiol Immunol; 2013 Jan 02; 364():61-90. PubMed ID: 23239349
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  • 11. Crystal structures of botulinum neurotoxin DC in complex with its protein receptors synaptotagmin I and II.
    Berntsson RP, Peng L, Svensson LM, Dong M, Stenmark P.
    Structure; 2013 Sep 03; 21(9):1602-11. PubMed ID: 23932591
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  • 12. Synaptotagmins I and II act as nerve cell receptors for botulinum neurotoxin G.
    Rummel A, Karnath T, Henke T, Bigalke H, Binz T.
    J Biol Chem; 2004 Jul 16; 279(29):30865-70. PubMed ID: 15123599
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  • 13. Botulinum neurotoxin D uses synaptic vesicle protein SV2 and gangliosides as receptors.
    Peng L, Tepp WH, Johnson EA, Dong M.
    PLoS Pathog; 2011 Mar 16; 7(3):e1002008. PubMed ID: 21483489
    [Abstract] [Full Text] [Related]

  • 14. Ganglioside GT1b as a complementary receptor component for Clostridium botulinum neurotoxins.
    Kozaki S, Kamata Y, Watarai S, Nishiki T, Mochida S.
    Microb Pathog; 1998 Aug 16; 25(2):91-9. PubMed ID: 9712688
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  • 15. Human synaptotagmin-II is not a high affinity receptor for botulinum neurotoxin B and G: increased therapeutic dosage and immunogenicity.
    Strotmeier J, Willjes G, Binz T, Rummel A.
    FEBS Lett; 2012 Feb 17; 586(4):310-3. PubMed ID: 22265973
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  • 16. Structural analysis of botulinum neurotoxin type G receptor binding .
    Schmitt J, Karalewitz A, Benefield DA, Mushrush DJ, Pruitt RN, Spiller BW, Barbieri JT, Lacy DB.
    Biochemistry; 2010 Jun 29; 49(25):5200-5. PubMed ID: 20507178
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  • 17. Synaptotagmin Binding to Botulinum Neurotoxins.
    Martínez-Carranza M, Blasco P, Gustafsson R, Dong M, Berntsson RP, Widmalm G, Stenmark P.
    Biochemistry; 2020 Feb 04; 59(4):491-498. PubMed ID: 31809018
    [Abstract] [Full Text] [Related]

  • 18. Synaptotagmins I and II mediate entry of botulinum neurotoxin B into cells.
    Dong M, Richards DA, Goodnough MC, Tepp WH, Johnson EA, Chapman ER.
    J Cell Biol; 2003 Sep 29; 162(7):1293-303. PubMed ID: 14504267
    [Abstract] [Full Text] [Related]

  • 19. Crystal structure of the botulinum neurotoxin type G binding domain: insight into cell surface binding.
    Stenmark P, Dong M, Dupuy J, Chapman ER, Stevens RC.
    J Mol Biol; 2010 Apr 16; 397(5):1287-97. PubMed ID: 20219474
    [Abstract] [Full Text] [Related]

  • 20. Knockin mouse models demonstrate differential contributions of synaptotagmin-1 and -2 as receptors for botulinum neurotoxins.
    Thaker H, Zhang J, Miyashita SI, Cristofaro V, Park S, Hashemi Gheinani A, Sullivan MP, Adam RM, Dong M.
    PLoS Pathog; 2021 Oct 16; 17(10):e1009994. PubMed ID: 34662366
    [Abstract] [Full Text] [Related]

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