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292 related items for PubMed ID: 22460705

  • 21. The IL-6- and lipopolysaccharide-induced transcription of hepcidin in HFE-, transferrin receptor 2-, and beta 2-microglobulin-deficient hepatocytes.
    Lee P, Peng H, Gelbart T, Beutler E.
    Proc Natl Acad Sci U S A; 2004 Jun 22; 101(25):9263-5. PubMed ID: 15192150
    [Abstract] [Full Text] [Related]

  • 22. [Pathophysiology and genetics of classic HFE (type 1) hemochromatosis].
    Loréal O, Ropert M, Mosser A, Déhais V, Deugnier Y, David V, Brissot P, Jouanolle AM.
    Presse Med; 2007 Sep 22; 36(9 Pt 2):1271-7. PubMed ID: 17521857
    [Abstract] [Full Text] [Related]

  • 23. Function of the hemochromatosis protein HFE: Lessons from animal models.
    Pantopoulos K.
    World J Gastroenterol; 2008 Dec 07; 14(45):6893-901. PubMed ID: 19058322
    [Abstract] [Full Text] [Related]

  • 24. Contribution of Hfe expression in macrophages to the regulation of hepatic hepcidin levels and iron loading.
    Makui H, Soares RJ, Jiang W, Constante M, Santos MM.
    Blood; 2005 Sep 15; 106(6):2189-95. PubMed ID: 15914561
    [Abstract] [Full Text] [Related]

  • 25. Bone morphogenetic proteins 2, 4, and 9 stimulate murine hepcidin 1 expression independently of Hfe, transferrin receptor 2 (Tfr2), and IL-6.
    Truksa J, Peng H, Lee P, Beutler E.
    Proc Natl Acad Sci U S A; 2006 Jul 05; 103(27):10289-10293. PubMed ID: 16801541
    [Abstract] [Full Text] [Related]

  • 26. Global loss of Tfr2 with concomitant induced iron deficiency greatly ameliorates the phenotype of a murine thalassemia intermedia model.
    Schmidt PJ, Fitzgerald K, Butler JS, Fleming MD.
    Am J Hematol; 2021 Feb 01; 96(2):251-257. PubMed ID: 33180328
    [Abstract] [Full Text] [Related]

  • 27. Expression of hepcidin is down-regulated in TfR2 mutant mice manifesting a phenotype of hereditary hemochromatosis.
    Kawabata H, Fleming RE, Gui D, Moon SY, Saitoh T, O'Kelly J, Umehara Y, Wano Y, Said JW, Koeffler HP.
    Blood; 2005 Jan 01; 105(1):376-81. PubMed ID: 15345587
    [Abstract] [Full Text] [Related]

  • 28. Hepatic iron metabolism gene expression profiles in HFE associated hereditary hemochromatosis.
    Gleeson F, Ryan E, Barrett S, Russell J, Crowe J.
    Blood Cells Mol Dis; 2007 Jan 01; 38(1):37-44. PubMed ID: 17098454
    [Abstract] [Full Text] [Related]

  • 29. Transferrin receptor 2 and HFE regulate furin expression via mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/Erk) signaling. Implications for transferrin-dependent hepcidin regulation.
    Poli M, Luscieti S, Gandini V, Maccarinelli F, Finazzi D, Silvestri L, Roetto A, Arosio P.
    Haematologica; 2010 Nov 01; 95(11):1832-40. PubMed ID: 20634490
    [Abstract] [Full Text] [Related]

  • 30. Hepcidin, a candidate modifier of the hemochromatosis phenotype in mice.
    Nicolas G, Andrews NC, Kahn A, Vaulont S.
    Blood; 2004 Apr 01; 103(7):2841-3. PubMed ID: 14656876
    [Abstract] [Full Text] [Related]

  • 31. Non-HFE hemochromatosis.
    Pietrangelo A.
    Semin Liver Dis; 2005 Nov 01; 25(4):450-60. PubMed ID: 16315138
    [Abstract] [Full Text] [Related]

  • 32. Hereditary hemochromatosis protein, HFE, interaction with transferrin receptor 2 suggests a molecular mechanism for mammalian iron sensing.
    Goswami T, Andrews NC.
    J Biol Chem; 2006 Sep 29; 281(39):28494-8. PubMed ID: 16893896
    [Abstract] [Full Text] [Related]

  • 33. Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice.
    Nicolas G, Bennoun M, Devaux I, Beaumont C, Grandchamp B, Kahn A, Vaulont S.
    Proc Natl Acad Sci U S A; 2001 Jul 17; 98(15):8780-5. PubMed ID: 11447267
    [Abstract] [Full Text] [Related]

  • 34. Tmprss6 is a genetic modifier of the Hfe-hemochromatosis phenotype in mice.
    Finberg KE, Whittlesey RL, Andrews NC.
    Blood; 2011 Apr 28; 117(17):4590-9. PubMed ID: 21355094
    [Abstract] [Full Text] [Related]

  • 35. HJV and HFE Play Distinct Roles in Regulating Hepcidin.
    Wu Q, Wang H, An P, Tao Y, Deng J, Zhang Z, Shen Y, Chen C, Min J, Wang F.
    Antioxid Redox Signal; 2015 May 20; 22(15):1325-36. PubMed ID: 25608116
    [Abstract] [Full Text] [Related]

  • 36. An RNAi therapeutic targeting Tmprss6 decreases iron overload in Hfe(-/-) mice and ameliorates anemia and iron overload in murine β-thalassemia intermedia.
    Schmidt PJ, Toudjarska I, Sendamarai AK, Racie T, Milstein S, Bettencourt BR, Hettinger J, Bumcrot D, Fleming MD.
    Blood; 2013 Feb 14; 121(7):1200-8. PubMed ID: 23223430
    [Abstract] [Full Text] [Related]

  • 37. A time course of hepcidin response to iron challenge in patients with HFE and TFR2 hemochromatosis.
    Girelli D, Trombini P, Busti F, Campostrini N, Sandri M, Pelucchi S, Westerman M, Ganz T, Nemeth E, Piperno A, Camaschella C.
    Haematologica; 2011 Apr 14; 96(4):500-6. PubMed ID: 21173098
    [Abstract] [Full Text] [Related]

  • 38. Hepcidin expression does not rescue the iron-poor phenotype of Kupffer cells in Hfe-null mice after liver transplantation.
    Garuti C, Tian Y, Montosi G, Sabelli M, Corradini E, Graf R, Ventura P, Vegetti A, Clavien PA, Pietrangelo A.
    Gastroenterology; 2010 Jul 14; 139(1):315-22.e1. PubMed ID: 20338170
    [Abstract] [Full Text] [Related]

  • 39. [HFE hemochromatosis: pathogenic and diagnostic approach].
    Brissot P, Le Lan C, Troadec MB, Lorho R, Ropert M, Lescoat G, Loréal O.
    Transfus Clin Biol; 2005 Jun 14; 12(2):77-82. PubMed ID: 15925529
    [Abstract] [Full Text] [Related]

  • 40. A critical role for murine transferrin receptor 2 in erythropoiesis during iron restriction.
    Wallace DF, Secondes ES, Rishi G, Ostini L, McDonald CJ, Lane SW, Vu T, Hooper JD, Velasco G, Ramsay AJ, Lopez-Otin C, Subramaniam VN.
    Br J Haematol; 2015 Mar 14; 168(6):891-901. PubMed ID: 25403101
    [Abstract] [Full Text] [Related]

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