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262 related items for PubMed ID: 22465052
21. A combination of sorafenib and SC-43 is a synergistic SHP-1 agonist duo to advance hepatocellular carcinoma therapy. Chao TI, Tai WT, Hung MH, Tsai MH, Chen MH, Chang MJ, Shiau CW, Chen KF. Cancer Lett; 2016 Feb 28; 371(2):205-13. PubMed ID: 26679051 [Abstract] [Full Text] [Related]
22. Inhibition of Bcl-2 improves effect of LCL161, a SMAC mimetic, in hepatocellular carcinoma cells. Chen KF, Lin JP, Shiau CW, Tai WT, Liu CY, Yu HC, Chen PJ, Cheng AL. Biochem Pharmacol; 2012 Aug 01; 84(3):268-77. PubMed ID: 22580047 [Abstract] [Full Text] [Related]
23. Sorafenib overcomes TRAIL resistance of hepatocellular carcinoma cells through the inhibition of STAT3. Chen KF, Tai WT, Liu TH, Huang HP, Lin YC, Shiau CW, Li PK, Chen PJ, Cheng AL. Clin Cancer Res; 2010 Nov 01; 16(21):5189-99. PubMed ID: 20884624 [Abstract] [Full Text] [Related]
24. Sorafenib enhances radiation-induced apoptosis in hepatocellular carcinoma by inhibiting STAT3. Huang CY, Lin CS, Tai WT, Hsieh CY, Shiau CW, Cheng AL, Chen KF. Int J Radiat Oncol Biol Phys; 2013 Jul 01; 86(3):456-62. PubMed ID: 23474115 [Abstract] [Full Text] [Related]
25. Identification of beta-escin as a novel inhibitor of signal transducer and activator of transcription 3/Janus-activated kinase 2 signaling pathway that suppresses proliferation and induces apoptosis in human hepatocellular carcinoma cells. Tan SM, Li F, Rajendran P, Kumar AP, Hui KM, Sethi G. J Pharmacol Exp Ther; 2010 Jul 01; 334(1):285-93. PubMed ID: 20378717 [Abstract] [Full Text] [Related]
26. Evodiamine inhibits STAT3 signaling by inducing phosphatase shatterproof 1 in hepatocellular carcinoma cells. Yang J, Cai X, Lu W, Hu C, Xu X, Yu Q, Cao P. Cancer Lett; 2013 Jan 28; 328(2):243-51. PubMed ID: 23032719 [Abstract] [Full Text] [Related]
28. Inhibition of growth and metastasis of human hepatocellular carcinoma by antisense oligonucleotide targeting signal transducer and activator of transcription 3. Li WC, Ye SL, Sun RX, Liu YK, Tang ZY, Kim Y, Karras JG, Zhang H. Clin Cancer Res; 2006 Dec 01; 12(23):7140-8. PubMed ID: 17145839 [Abstract] [Full Text] [Related]
29. Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3. Subramaniam A, Shanmugam MK, Ong TH, Li F, Perumal E, Chen L, Vali S, Abbasi T, Kapoor S, Ahn KS, Kumar AP, Hui KM, Sethi G. Br J Pharmacol; 2013 Oct 01; 170(4):807-21. PubMed ID: 23848338 [Abstract] [Full Text] [Related]
30. CADPE suppresses cyclin D1 expression in hepatocellular carcinoma by blocking IL-6-induced STAT3 activation. Won C, Lee CS, Lee JK, Kim TJ, Lee KH, Yang YM, Kim YN, Ye SK, Chung MH. Anticancer Res; 2010 Feb 01; 30(2):481-8. PubMed ID: 20332458 [Abstract] [Full Text] [Related]
32. Novel sorafenib analogues induce apoptosis through SHP-1 dependent STAT3 inactivation in human breast cancer cells. Liu CY, Tseng LM, Su JC, Chang KC, Chu PY, Tai WT, Shiau CW, Chen KF. Breast Cancer Res; 2013 Feb 01; 15(4):R63. PubMed ID: 23938089 [Abstract] [Full Text] [Related]
33. Discovery of novel Src homology region 2 domain-containing phosphatase 1 agonists from sorafenib for the treatment of hepatocellular carcinoma. Tai WT, Shiau CW, Chen PJ, Chu PY, Huang HP, Liu CY, Huang JW, Chen KF. Hepatology; 2014 Jan 01; 59(1):190-201. PubMed ID: 23908138 [Abstract] [Full Text] [Related]
36. Suppression of Mcl-1 via RNA interference sensitizes human hepatocellular carcinoma cells towards apoptosis induction. Schulze-Bergkamen H, Fleischer B, Schuchmann M, Weber A, Weinmann A, Krammer PH, Galle PR. BMC Cancer; 2006 Oct 02; 6():232. PubMed ID: 17014711 [Abstract] [Full Text] [Related]
37. Capillarisin inhibits constitutive and inducible STAT3 activation through induction of SHP-1 and SHP-2 tyrosine phosphatases. Lee JH, Chiang SY, Nam D, Chung WS, Lee J, Na YS, Sethi G, Ahn KS. Cancer Lett; 2014 Apr 01; 345(1):140-8. PubMed ID: 24333736 [Abstract] [Full Text] [Related]
38. Diosgenin, a steroidal saponin, inhibits STAT3 signaling pathway leading to suppression of proliferation and chemosensitization of human hepatocellular carcinoma cells. Li F, Fernandez PP, Rajendran P, Hui KM, Sethi G. Cancer Lett; 2010 Jun 28; 292(2):197-207. PubMed ID: 20053498 [Abstract] [Full Text] [Related]
39. Synthesis and biological activity of obatoclax derivatives as novel and potent SHP-1 agonists. Su JC, Chen KF, Chen WL, Liu CY, Huang JW, Tai WT, Chen PJ, Kim I, Shiau CW. Eur J Med Chem; 2012 Oct 28; 56():127-33. PubMed ID: 22982119 [Abstract] [Full Text] [Related]
40. Sequential combination of docetaxel with a SHP-1 agonist enhanced suppression of p-STAT3 signaling and apoptosis in triple negative breast cancer cells. Liu CY, Chen KF, Chao TI, Chu PY, Huang CT, Huang TT, Yang HP, Wang WL, Lee CH, Lau KY, Tsai WC, Su JC, Wu CY, Chen MH, Shiau CW, Tseng LM. J Mol Med (Berl); 2017 Sep 28; 95(9):965-975. PubMed ID: 28578456 [Abstract] [Full Text] [Related] Page: [Previous] [Next] [New Search]