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Journal Abstract Search

602 related items for PubMed ID: 22472046

  • 1. Inhibition of cholinesterase activity and amyloid aggregation by berberine-phenyl-benzoheterocyclic and tacrine-phenyl-benzoheterocyclic hybrids.
    Huang L, Su T, Shan W, Luo Z, Sun Y, He F, Li X.
    Bioorg Med Chem; 2012 May 01; 20(9):3038-48. PubMed ID: 22472046
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  • 2. O-Hydroxyl- or o-amino benzylamine-tacrine hybrids: multifunctional biometals chelators, antioxidants, and inhibitors of cholinesterase activity and amyloid-β aggregation.
    Mao F, Huang L, Luo Z, Liu A, Lu C, Xie Z, Li X.
    Bioorg Med Chem; 2012 Oct 01; 20(19):5884-92. PubMed ID: 22944335
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  • 3. Design, synthesis and evaluation of novel tacrine-multialkoxybenzene hybrids as dual inhibitors for cholinesterases and amyloid beta aggregation.
    Luo W, Li YP, He Y, Huang SL, Tan JH, Ou TM, Li D, Gu LQ, Huang ZS.
    Bioorg Med Chem; 2011 Jan 15; 19(2):763-70. PubMed ID: 21211982
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  • 4. Synthesis and biological evaluation of berberine-thiophenyl hybrids as multi-functional agents: Inhibition of acetylcholinesterase, butyrylcholinesterase, and Aβ aggregation and antioxidant activity.
    Su T, Xie S, Wei H, Yan J, Huang L, Li X.
    Bioorg Med Chem; 2013 Sep 15; 21(18):5830-40. PubMed ID: 23932451
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  • 5. Synthesis, biological evaluation of 9-N-substituted berberine derivatives as multi-functional agents of antioxidant, inhibitors of acetylcholinesterase, butyrylcholinesterase and amyloid-β aggregation.
    Shan WJ, Huang L, Zhou Q, Meng FC, Li XS.
    Eur J Med Chem; 2011 Dec 15; 46(12):5885-93. PubMed ID: 22019228
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  • 8. Syntheses of coumarin-tacrine hybrids as dual-site acetylcholinesterase inhibitors and their activity against butylcholinesterase, Aβ aggregation, and β-secretase.
    Sun Q, Peng DY, Yang SG, Zhu XL, Yang WC, Yang GF.
    Bioorg Med Chem; 2014 Sep 01; 22(17):4784-91. PubMed ID: 25088549
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  • 11. Hybrids of oxoisoaporphine-tacrine congeners: novel acetylcholinesterase and acetylcholinesterase-induced β-amyloid aggregation inhibitors.
    Tang H, Zhao LZ, Zhao HT, Huang SL, Zhong SM, Qin JK, Chen ZF, Huang ZS, Liang H.
    Eur J Med Chem; 2011 Oct 01; 46(10):4970-9. PubMed ID: 21871694
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  • 12. Multipotent MAO and cholinesterase inhibitors for the treatment of Alzheimer's disease: synthesis, pharmacological analysis and molecular modeling of heterocyclic substituted alkyl and cycloalkyl propargyl amine.
    Samadi A, de los Ríos C, Bolea I, Chioua M, Iriepa I, Moraleda I, Bartolini M, Andrisano V, Gálvez E, Valderas C, Unzeta M, Marco-Contelles J.
    Eur J Med Chem; 2012 Jun 01; 52():251-62. PubMed ID: 22503231
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  • 13. Synthesis, pharmacology and molecular docking on multifunctional tacrine-ferulic acid hybrids as cholinesterase inhibitors against Alzheimer's disease.
    Zhu J, Yang H, Chen Y, Lin H, Li Q, Mo J, Bian Y, Pei Y, Sun H.
    J Enzyme Inhib Med Chem; 2018 Dec 01; 33(1):496-506. PubMed ID: 29405075
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  • 14. Design, synthesis and evaluation of novel tacrine-(β-carboline) hybrids as multifunctional agents for the treatment of Alzheimer's disease.
    Lan JS, Xie SS, Li SY, Pan LF, Wang XB, Kong LY.
    Bioorg Med Chem; 2014 Nov 01; 22(21):6089-104. PubMed ID: 25282654
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  • 15. Design, synthesis and pharmacological evaluation of novel tacrine-caffeic acid hybrids as multi-targeted compounds against Alzheimer's disease.
    Chao X, He X, Yang Y, Zhou X, Jin M, Liu S, Cheng Z, Liu P, Wang Y, Yu J, Tan Y, Huang Y, Qin J, Rapposelli S, Pi R.
    Bioorg Med Chem Lett; 2012 Oct 15; 22(20):6498-502. PubMed ID: 22981331
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  • 16. New tacrine-4-oxo-4H-chromene hybrids as multifunctional agents for the treatment of Alzheimer's disease, with cholinergic, antioxidant, and β-amyloid-reducing properties.
    Fernández-Bachiller MI, Pérez C, Monjas L, Rademann J, Rodríguez-Franco MI.
    J Med Chem; 2012 Feb 09; 55(3):1303-17. PubMed ID: 22243648
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  • 17. Novel tacrine-ebselen hybrids with improved cholinesterase inhibitory, hydrogen peroxide and peroxynitrite scavenging activity.
    Mao F, Chen J, Zhou Q, Luo Z, Huang L, Li X.
    Bioorg Med Chem Lett; 2013 Dec 15; 23(24):6737-42. PubMed ID: 24220172
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  • 18. Design, synthesis and biological activity of novel tacrine-isatin Schiff base hybrid derivatives.
    Riazimontazer E, Sadeghpour H, Nadri H, Sakhteman A, Tüylü Küçükkılınç T, Miri R, Edraki N.
    Bioorg Chem; 2019 Aug 15; 89():103006. PubMed ID: 31158577
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  • 19. Design, synthesis and neuroprotective evaluation of novel tacrine-benzothiazole hybrids as multi-targeted compounds against Alzheimer's disease.
    Keri RS, Quintanova C, Marques SM, Esteves AR, Cardoso SM, Santos MA.
    Bioorg Med Chem; 2013 Aug 01; 21(15):4559-69. PubMed ID: 23768661
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  • 20. Synthesis, biological evaluation and molecular modeling study of novel tacrine-carbazole hybrids as potential multifunctional agents for the treatment of Alzheimer's disease.
    Thiratmatrakul S, Yenjai C, Waiwut P, Vajragupta O, Reubroycharoen P, Tohda M, Boonyarat C.
    Eur J Med Chem; 2014 Mar 21; 75():21-30. PubMed ID: 24508831
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