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Journal Abstract Search

251 related items for PubMed ID: 22473991

  • 1. Fbw7 and p53 cooperatively suppress advanced and chromosomally unstable intestinal cancer.
    Grim JE, Knoblaugh SE, Guthrie KA, Hagar A, Swanger J, Hespelt J, Delrow JJ, Small T, Grady WM, Nakayama KI, Clurman BE.
    Mol Cell Biol; 2012 Jun; 32(11):2160-7. PubMed ID: 22473991
    [Abstract] [Full Text] [Related]

  • 2. FBW7 mutations mediate resistance of colorectal cancer to targeted therapies by blocking Mcl-1 degradation.
    Tong J, Tan S, Zou F, Yu J, Zhang L.
    Oncogene; 2017 Feb 09; 36(6):787-796. PubMed ID: 27399335
    [Abstract] [Full Text] [Related]

  • 3. F-box and WD repeat domain-containing 7 regulates intestinal cell lineage commitment and is a haploinsufficient tumor suppressor.
    Sancho R, Jandke A, Davis H, Diefenbacher ME, Tomlinson I, Behrens A.
    Gastroenterology; 2010 Sep 09; 139(3):929-41. PubMed ID: 20638938
    [Abstract] [Full Text] [Related]

  • 4. Global and context-specific transcriptional consequences of oncogenic Fbw7 mutations.
    Thirimanne HN, Wu F, Janssens DH, Swanger J, Diab A, Feldman HM, Amezquita RA, Gottardo R, Paddison PJ, Henikoff S, Clurman BE.
    Elife; 2022 Feb 28; 11():. PubMed ID: 35225231
    [Abstract] [Full Text] [Related]

  • 5. Aberrant regulation of FBW7 in cancer.
    Wang L, Ye X, Liu Y, Wei W, Wang Z.
    Oncotarget; 2014 Apr 30; 5(8):2000-15. PubMed ID: 24899581
    [Abstract] [Full Text] [Related]

  • 6. The two faces of FBW7 in cancer drug resistance.
    Wang Z, Fukushima H, Gao D, Inuzuka H, Wan L, Lau AW, Liu P, Wei W.
    Bioessays; 2011 Nov 30; 33(11):851-9. PubMed ID: 22006825
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  • 7. ERK kinase phosphorylates and destabilizes the tumor suppressor FBW7 in pancreatic cancer.
    Ji S, Qin Y, Shi S, Liu X, Hu H, Zhou H, Gao J, Zhang B, Xu W, Liu J, Liang D, Liu L, Liu C, Long J, Zhou H, Chiao PJ, Xu J, Ni Q, Gao D, Yu X.
    Cell Res; 2015 May 30; 25(5):561-73. PubMed ID: 25753158
    [Abstract] [Full Text] [Related]

  • 8. Recombinant human adenovirus-p53 injection induced apoptosis in hepatocellular carcinoma cell lines mediated by p53-Fbxw7 pathway, which controls c-Myc and cyclin E.
    Tu K, Zheng X, Zhou Z, Li C, Zhang J, Gao J, Yao Y, Liu Q.
    PLoS One; 2013 May 30; 8(7):e68574. PubMed ID: 23840897
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  • 12. Regulation of GATA-binding protein 2 levels via ubiquitin-dependent degradation by Fbw7: involvement of cyclin B-cyclin-dependent kinase 1-mediated phosphorylation of THR176 in GATA-binding protein 2.
    Nakajima T, Kitagawa K, Ohhata T, Sakai S, Uchida C, Shibata K, Minegishi N, Yumimoto K, Nakayama KI, Masumoto K, Katou F, Niida H, Kitagawa M.
    J Biol Chem; 2015 Apr 17; 290(16):10368-81. PubMed ID: 25670854
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  • 13. Chromosome instability underlies hematopoietic stem cell dysfunction and lymphoid neoplasia associated with impaired Fbw7-mediated cyclin E regulation.
    Siu KT, Xu Y, Swartz KL, Bhattacharyya M, Gurbuxani S, Hua Y, Minella AC.
    Mol Cell Biol; 2014 Sep 17; 34(17):3244-58. PubMed ID: 24958101
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  • 15. FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation.
    Welcker M, Clurman BE.
    Nat Rev Cancer; 2008 Feb 17; 8(2):83-93. PubMed ID: 18094723
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  • 17. SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.
    Inuzuka H, Shaik S, Onoyama I, Gao D, Tseng A, Maser RS, Zhai B, Wan L, Gutierrez A, Lau AW, Xiao Y, Christie AL, Aster J, Settleman J, Gygi SP, Kung AL, Look T, Nakayama KI, DePinho RA, Wei W.
    Nature; 2011 Mar 03; 471(7336):104-9. PubMed ID: 21368833
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  • 18. MicroRNA-223 regulates cyclin E activity by modulating expression of F-box and WD-40 domain protein 7.
    Xu Y, Sengupta T, Kukreja L, Minella AC.
    J Biol Chem; 2010 Nov 05; 285(45):34439-46. PubMed ID: 20826802
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  • 19. A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size.
    Welcker M, Orian A, Grim JE, Eisenman RN, Clurman BE.
    Curr Biol; 2004 Oct 26; 14(20):1852-7. PubMed ID: 15498494
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  • 20. CDC4 mutations occur in a subset of colorectal cancers but are not predicted to cause loss of function and are not associated with chromosomal instability.
    Kemp Z, Rowan A, Chambers W, Wortham N, Halford S, Sieber O, Mortensen N, von Herbay A, Gunther T, Ilyas M, Tomlinson I.
    Cancer Res; 2005 Dec 15; 65(24):11361-6. PubMed ID: 16357143
    [Abstract] [Full Text] [Related]

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