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292 related items for PubMed ID: 22480737
1. Inhibition of thymidine phosphorylase expression by using an HSP90 inhibitor potentiates the cytotoxic effect of cisplatin in non-small-cell lung cancer cells. Weng SH, Tseng SC, Huang YC, Chen HJ, Lin YW. Biochem Pharmacol; 2012 Jul 01; 84(1):126-36. PubMed ID: 22480737 [Abstract] [Full Text] [Related]
2. HSP90 inhibition induces cytotoxicity via down-regulation of Rad51 expression and DNA repair capacity in non-small cell lung cancer cells. Ko JC, Chen HJ, Huang YC, Tseng SC, Weng SH, Wo TY, Huang YJ, Chiu HC, Tsai MS, Chiou RY, Lin YW. Regul Toxicol Pharmacol; 2012 Dec 01; 64(3):415-24. PubMed ID: 23069143 [Abstract] [Full Text] [Related]
3. Up-regulation of extracellular signal-regulated kinase 1/2-dependent thymidylate synthase and thymidine phosphorylase contributes to cisplatin resistance in human non-small-cell lung cancer cells. Ko JC, Tsai MS, Chiu YF, Weng SH, Kuo YH, Lin YW. J Pharmacol Exp Ther; 2011 Jul 01; 338(1):184-94. PubMed ID: 21444628 [Abstract] [Full Text] [Related]
4. Tamoxifen enhances erlotinib-induced cytotoxicity through down-regulating AKT-mediated thymidine phosphorylase expression in human non-small-cell lung cancer cells. Ko JC, Chiu HC, Syu JJ, Jian YJ, Chen CY, Jian YT, Huang YJ, Wo TY, Lin YW. Biochem Pharmacol; 2014 Mar 01; 88(1):119-27. PubMed ID: 24447935 [Abstract] [Full Text] [Related]
5. Heat shock protein 90 inhibitor 17-AAG down-regulates thymidine phosphorylase expression and potentiates the cytotoxic effect of tamoxifen and erlotinib in human lung squamous carcinoma cells. Ko JC, Chen JC, Hsieh JM, Tseng PY, Chiang CS, Liu LL, Chien CC, Huang IH, Chang QZ, Mu BC, Lin YW. Biochem Pharmacol; 2022 Oct 01; 204():115207. PubMed ID: 35961402 [Abstract] [Full Text] [Related]
6. Inhibition of thymidine phosphorylase expression by Hsp90 inhibitor potentiates the cytotoxic effect of salinomycin in human non-small-cell lung cancer cells. Ko JC, Chen JC, Chen TY, Yen TC, Ma PF, Lin YC, Wu CH, Peng YS, Zheng HY, Lin YW. Toxicology; 2019 Apr 01; 417():54-63. PubMed ID: 30796972 [Abstract] [Full Text] [Related]
7. Synergistic effect of curcumin and cisplatin via down-regulation of thymidine phosphorylase and excision repair cross-complementary 1 (ERCC1). Tsai MS, Weng SH, Kuo YH, Chiu YF, Lin YW. Mol Pharmacol; 2011 Jul 01; 80(1):136-46. PubMed ID: 21493726 [Abstract] [Full Text] [Related]
8. 17-AAG and 17-DMAG-induced inhibition of cell proliferation through B-Raf downregulation in WT B-Raf-expressing uveal melanoma cell lines. Babchia N, Calipel A, Mouriaux F, Faussat AM, Mascarelli F. Invest Ophthalmol Vis Sci; 2008 Jun 01; 49(6):2348-56. PubMed ID: 18281615 [Abstract] [Full Text] [Related]
9. Enhancement of mitomycin C-induced cytotoxicity by curcumin results from down-regulation of MKK1/2-ERK1/2-mediated thymidine phosphorylase expression. Weng SH, Tsai MS, Chiu YF, Kuo YH, Chen HJ, Lin YW. Basic Clin Pharmacol Toxicol; 2012 Mar 01; 110(3):298-306. PubMed ID: 21973306 [Abstract] [Full Text] [Related]
10. Downregulation of Xeroderma Pigmentosum Complementation Group C Expression by 17-Allylamino-17-Demethoxygeldanamycin Enhances Bevacizumab-Induced Cytotoxicity in Human Lung Cancer Cells. Chen JC, Ko JC, Taso YC, Cheng HH, Chen TY, Yen TC, Lin YW. Pharmacology; 2021 Mar 01; 106(3-4):154-168. PubMed ID: 33202406 [Abstract] [Full Text] [Related]
11. Roles of MKK1/2-ERK1/2 and phosphoinositide 3-kinase-AKT signaling pathways in erlotinib-induced Rad51 suppression and cytotoxicity in human non-small cell lung cancer cells. Ko JC, Ciou SC, Jhan JY, Cheng CM, Su YJ, Chuang SM, Lin ST, Chang CC, Lin YW. Mol Cancer Res; 2009 Aug 01; 7(8):1378-89. PubMed ID: 19671683 [Abstract] [Full Text] [Related]
12. Emodin enhances cisplatin-induced cytotoxicity via down-regulation of ERCC1 and inactivation of ERK1/2. Ko JC, Su YJ, Lin ST, Jhan JY, Ciou SC, Cheng CM, Chiu YF, Kuo YH, Tsai MS, Lin YW. Lung Cancer; 2010 Aug 01; 69(2):155-64. PubMed ID: 19962780 [Abstract] [Full Text] [Related]
13. Curcumin enhances the mitomycin C-induced cytotoxicity via downregulation of MKK1/2-ERK1/2-mediated Rad51 expression in non-small cell lung cancer cells. Ko JC, Tsai MS, Weng SH, Kuo YH, Chiu YF, Lin YW. Toxicol Appl Pharmacol; 2011 Sep 15; 255(3):327-38. PubMed ID: 21810436 [Abstract] [Full Text] [Related]
14. The heat-shock protein 90 inhibitor, geldanamycin, induces apoptotic cell death in Epstein-Barr virus-positive NK/T-cell lymphoma by Akt down-regulation. Jeon YK, Park CH, Kim KY, Li YC, Kim J, Kim YA, Paik JH, Park BK, Kim CW, Kim YN. J Pathol; 2007 Oct 15; 213(2):170-9. PubMed ID: 17768706 [Abstract] [Full Text] [Related]
15. Down-regulation of MSH2 expression by an Hsp90 inhibitor enhances pemetrexed-induced cytotoxicity in human non-small-cell lung cancer cells. Tung CL, Chiu HC, Jian YJ, Jian YT, Chen CY, Syu JJ, Wo TY, Huang YJ, Tseng SC, Lin YW. Exp Cell Res; 2014 Apr 01; 322(2):345-54. PubMed ID: 24530475 [Abstract] [Full Text] [Related]
16. Multiple kinase pathways involved in the different de novo sensitivity of pancreatic cancer cell lines to 17-AAG. Liu H, Zhang T, Chen R, McConkey DJ, Ward JF, Curley SA. J Surg Res; 2012 Jul 01; 176(1):147-53. PubMed ID: 22099584 [Abstract] [Full Text] [Related]
17. Inhibition of heat shock protein 90 function by 17-allylamino-17-demethoxy-geldanamycin in Hodgkin's lymphoma cells down-regulates Akt kinase, dephosphorylates extracellular signal-regulated kinase, and induces cell cycle arrest and cell death. Georgakis GV, Li Y, Rassidakis GZ, Martinez-Valdez H, Medeiros LJ, Younes A. Clin Cancer Res; 2006 Jan 15; 12(2):584-90. PubMed ID: 16428504 [Abstract] [Full Text] [Related]
18. Modulation of Rad51, ERCC1, and thymidine phosphorylase by emodin result in synergistic cytotoxic effect in combination with capecitabine. Ko JC, Tsai MS, Kuo YH, Chiu YF, Weng SH, Su YC, Lin YW. Biochem Pharmacol; 2011 Mar 01; 81(5):680-90. PubMed ID: 21168393 [Abstract] [Full Text] [Related]
19. 17-Allylamino-17-demethoxygeldanamycin and ritonavir inhibit renal cancer growth by inhibiting the expression of heat shock factor-1. Sato A, Asano T, Ito K, Asano T. Int J Oncol; 2012 Jul 01; 41(1):46-52. PubMed ID: 22470109 [Abstract] [Full Text] [Related]
20. Anti-proliferative activity of heat shock protein (Hsp) 90 inhibitors via beta-catenin/TCF7L2 pathway in adult T cell leukemia cells. Kurashina R, Ohyashiki JH, Kobayashi C, Hamamura R, Zhang Y, Hirano T, Ohyashiki K. Cancer Lett; 2009 Oct 18; 284(1):62-70. PubMed ID: 19464103 [Abstract] [Full Text] [Related] Page: [Next] [New Search]