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Journal Abstract Search

590 related items for PubMed ID: 22482799

  • 1. Specific disruption of transthyretin(105-115) fibrilization using "stabilizing" inhibitors of transthyretin amyloidogenesis.
    Liang Y, Ore MO, Morin S, Wilson DJ.
    Biochemistry; 2012 Apr 24; 51(16):3523-30. PubMed ID: 22482799
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and characterization of potent bivalent amyloidosis inhibitors that bind prior to transthyretin tetramerization.
    Green NS, Palaninathan SK, Sacchettini JC, Kelly JW.
    J Am Chem Soc; 2003 Nov 05; 125(44):13404-14. PubMed ID: 14583036
    [Abstract] [Full Text] [Related]

  • 3. Chromium(III) ion and thyroxine cooperate to stabilize the transthyretin tetramer and suppress in vitro amyloid fibril formation.
    Sato T, Ando Y, Susuki S, Mikami F, Ikemizu S, Nakamura M, Suhr O, Anraku M, Kai T, Suico MA, Shuto T, Mizuguchi M, Yamagata Y, Kai H.
    FEBS Lett; 2006 Jan 23; 580(2):491-6. PubMed ID: 16386248
    [Abstract] [Full Text] [Related]

  • 4. Genistein, a natural product from soy, is a potent inhibitor of transthyretin amyloidosis.
    Green NS, Foss TR, Kelly JW.
    Proc Natl Acad Sci U S A; 2005 Oct 11; 102(41):14545-50. PubMed ID: 16195386
    [Abstract] [Full Text] [Related]

  • 5. Clusterin regulates transthyretin amyloidosis.
    Lee KW, Lee DH, Son H, Kim YS, Park JY, Roh GS, Kim HJ, Kang SS, Cho GJ, Choi WS.
    Biochem Biophys Res Commun; 2009 Oct 16; 388(2):256-60. PubMed ID: 19664600
    [Abstract] [Full Text] [Related]

  • 6. Cyclodextrin, a novel therapeutic tool for suppressing amyloidogenic transthyretin misfolding in transthyretin-related amyloidosis.
    Jono H, Anno T, Motoyama K, Misumi Y, Tasaki M, Oshima T, Mori Y, Mizuguchi M, Ueda M, Shono M, Obayashi K, Arima H, Ando Y.
    Biochem J; 2011 Jul 01; 437(1):35-42. PubMed ID: 21668413
    [Abstract] [Full Text] [Related]

  • 7. Uncovering the Mechanism of Aggregation of Human Transthyretin.
    Saelices L, Johnson LM, Liang WY, Sawaya MR, Cascio D, Ruchala P, Whitelegge J, Jiang L, Riek R, Eisenberg DS.
    J Biol Chem; 2015 Nov 27; 290(48):28932-43. PubMed ID: 26459562
    [Abstract] [Full Text] [Related]

  • 8. Potent and selective structure-based dibenzofuran inhibitors of transthyretin amyloidogenesis: kinetic stabilization of the native state.
    Petrassi HM, Johnson SM, Purkey HE, Chiang KP, Walkup T, Jiang X, Powers ET, Kelly JW.
    J Am Chem Soc; 2005 May 11; 127(18):6662-71. PubMed ID: 15869287
    [Abstract] [Full Text] [Related]

  • 9. Cys10 mixed disulfides make transthyretin more amyloidogenic under mildly acidic conditions.
    Zhang Q, Kelly JW.
    Biochemistry; 2003 Jul 29; 42(29):8756-61. PubMed ID: 12873136
    [Abstract] [Full Text] [Related]

  • 10. Selective binding to transthyretin and tetramer stabilization in serum from patients with familial amyloidotic polyneuropathy by an iodinated diflunisal derivative.
    Almeida MR, Macedo B, Cardoso I, Alves I, Valencia G, Arsequell G, Planas A, Saraiva MJ.
    Biochem J; 2004 Jul 15; 381(Pt 2):351-6. PubMed ID: 15080795
    [Abstract] [Full Text] [Related]

  • 11. D18G transthyretin is monomeric, aggregation prone, and not detectable in plasma and cerebrospinal fluid: a prescription for central nervous system amyloidosis?
    Hammarström P, Sekijima Y, White JT, Wiseman RL, Lim A, Costello CE, Altland K, Garzuly F, Budka H, Kelly JW.
    Biochemistry; 2003 Jun 10; 42(22):6656-63. PubMed ID: 12779320
    [Abstract] [Full Text] [Related]

  • 12. Kinetic stabilization of an oligomeric protein under physiological conditions demonstrated by a lack of subunit exchange: implications for transthyretin amyloidosis.
    Wiseman RL, Green NS, Kelly JW.
    Biochemistry; 2005 Jun 28; 44(25):9265-74. PubMed ID: 15966751
    [Abstract] [Full Text] [Related]

  • 13. Amyloid deposits in transthyretin-derived amyloidosis: cleaved transthyretin is associated with distinct amyloid morphology.
    Bergström J, Gustavsson A, Hellman U, Sletten K, Murphy CL, Weiss DT, Solomon A, Olofsson BO, Westermark P.
    J Pathol; 2005 Jun 28; 206(2):224-32. PubMed ID: 15810051
    [Abstract] [Full Text] [Related]

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  • 15. Diflunisal stabilizes familial amyloid polyneuropathy-associated transthyretin variant tetramers in serum against dissociation required for amyloidogenesis.
    Tojo K, Sekijima Y, Kelly JW, Ikeda S.
    Neurosci Res; 2006 Dec 28; 56(4):441-9. PubMed ID: 17028027
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  • 17. Amyloid disease prevention by transthyretin native state complexation with carborane derivatives lacking cyclooxygenase inhibition.
    Julius RL, Hawthorne MF.
    Drug News Perspect; 2008 Jun 28; 21(5):258-66. PubMed ID: 18596990
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  • 19. Transthyretin Misfolding, A Fatal Structural Pathogenesis Mechanism.
    Si JB, Kim B, Kim JH.
    Int J Mol Sci; 2021 Apr 23; 22(9):. PubMed ID: 33922648
    [Abstract] [Full Text] [Related]

  • 20. Mechanisms of transthyretin aggregation and toxicity.
    Gasperini RJ, Klaver DW, Hou X, Aguilar MI, Small DH.
    Subcell Biochem; 2012 Apr 23; 65():211-24. PubMed ID: 23225005
    [Abstract] [Full Text] [Related]

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