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473 related items for PubMed ID: 22484513

  • 1. Comparison of hepatocarcinogen-induced gene expression profiles in conventional primary rat hepatocytes with in vivo rat liver.
    Doktorova TY, Ellinger-Ziegelbauer H, Vinken M, Vanhaecke T, van Delft J, Kleinjans J, Ahr HJ, Rogiers V.
    Arch Toxicol; 2012 Sep; 86(9):1399-411. PubMed ID: 22484513
    [Abstract] [Full Text] [Related]

  • 2. Comparison of the expression profiles induced by genotoxic and nongenotoxic carcinogens in rat liver.
    Ellinger-Ziegelbauer H, Stuart B, Wahle B, Bomann W, Ahr HJ.
    Mutat Res; 2005 Aug 04; 575(1-2):61-84. PubMed ID: 15890375
    [Abstract] [Full Text] [Related]

  • 3. Characteristic expression profiles induced by genotoxic carcinogens in rat liver.
    Ellinger-Ziegelbauer H, Stuart B, Wahle B, Bomann W, Ahr HJ.
    Toxicol Sci; 2004 Jan 04; 77(1):19-34. PubMed ID: 14600272
    [Abstract] [Full Text] [Related]

  • 4. Comparison of genotoxicant-modified transcriptomic responses in conventional and epigenetically stabilized primary rat hepatocytes with in vivo rat liver data.
    Doktorova TY, Ellinger-Ziegelbauer H, Vinken M, Vanhaecke T, van Delft J, Kleinjans J, Ahr HJ, Rogiers V.
    Arch Toxicol; 2012 Nov 04; 86(11):1703-15. PubMed ID: 23052194
    [Abstract] [Full Text] [Related]

  • 5. Transcriptomic responses generated by hepatocarcinogens in a battery of liver-based in vitro models.
    Doktorova TY, Yildirimman R, Vinken M, Vilardell M, Vanhaecke T, Gmuender H, Bort R, Brolen G, Holmgren G, Li R, Chesne C, van Delft J, Kleinjans J, Castell J, Bjorquist P, Herwig R, Rogiers V.
    Carcinogenesis; 2013 Jun 04; 34(6):1393-402. PubMed ID: 23393228
    [Abstract] [Full Text] [Related]

  • 6. Prediction of a carcinogenic potential of rat hepatocarcinogens using toxicogenomics analysis of short-term in vivo studies.
    Ellinger-Ziegelbauer H, Gmuender H, Bandenburg A, Ahr HJ.
    Mutat Res; 2008 Jan 01; 637(1-2):23-39. PubMed ID: 17689568
    [Abstract] [Full Text] [Related]

  • 7. A toxicogenomics approach for early assessment of potential non-genotoxic hepatocarcinogenicity of chemicals in rats.
    Uehara T, Hirode M, Ono A, Kiyosawa N, Omura K, Shimizu T, Mizukawa Y, Miyagishima T, Nagao T, Urushidani T.
    Toxicology; 2008 Aug 19; 250(1):15-26. PubMed ID: 18619722
    [Abstract] [Full Text] [Related]

  • 8. Benzo[a]pyrene-induced transcriptomic responses in primary hepatocytes and in vivo liver: toxicokinetics is essential for in vivo-in vitro comparisons.
    van Kesteren PC, Zwart PE, Schaap MM, Pronk TE, van Herwijnen MH, Kleinjans JC, Bokkers BG, Godschalk RW, Zeilmaker MJ, van Steeg H, Luijten M.
    Arch Toxicol; 2013 Mar 19; 87(3):505-15. PubMed ID: 23052197
    [Abstract] [Full Text] [Related]

  • 9. Differential gene expression profiling between genotoxic and non-genotoxic hepatocarcinogens in young rat liver determined by quantitative real-time PCR and principal component analysis.
    Suenaga K, Takasawa H, Watanabe T, Wako Y, Suzuki T, Hamada S, Furihata C.
    Mutat Res; 2013 Feb 18; 751(1):73-83. PubMed ID: 23183053
    [Abstract] [Full Text] [Related]

  • 10. Identification of specific mRNA signatures as fingerprints for carcinogenesis in mice induced by genotoxic and nongenotoxic hepatocarcinogens.
    Kossler N, Matheis KA, Ostenfeldt N, Bach Toft D, Dhalluin S, Deschl U, Kalkuhl A.
    Toxicol Sci; 2015 Feb 18; 143(2):277-95. PubMed ID: 25410580
    [Abstract] [Full Text] [Related]

  • 11. Identification of early target genes of aflatoxin B1 in human hepatocytes, inter-individual variability and comparison with other genotoxic compounds.
    Josse R, Dumont J, Fautrel A, Robin MA, Guillouzo A.
    Toxicol Appl Pharmacol; 2012 Jan 15; 258(2):176-87. PubMed ID: 22100608
    [Abstract] [Full Text] [Related]

  • 12. Discrimination of genotoxic and non-genotoxic hepatocarcinogens by statistical analysis based on gene expression profiling in the mouse liver as determined by quantitative real-time PCR.
    Watanabe T, Suzuki T, Natsume M, Nakajima M, Narumi K, Hamada S, Sakuma T, Koeda A, Oshida K, Miyamoto Y, Maeda A, Hirayama M, Sanada H, Honda H, Ohyama W, Okada E, Fujiishi Y, Sutou S, Tadakuma A, Ishikawa Y, Kido M, Minamiguchi R, Hanahara I, Furihata C.
    Mutat Res; 2012 Sep 18; 747(2):164-75. PubMed ID: 22634710
    [Abstract] [Full Text] [Related]

  • 13. In vitro - in vivo correlation of gene expression alterations induced by liver carcinogens.
    Heise T, Schug M, Storm D, Ellinger-Ziegelbauer H, Ahr HJ, Hellwig B, Rahnenfuhrer J, Ghallab A, Guenther G, Sisnaiske J, Reif R, Godoy P, Mielke H, Gundert-Remy U, Lampen A, Oberemm A, Hengstler JG.
    Curr Med Chem; 2012 Sep 18; 19(11):1721-30. PubMed ID: 22414088
    [Abstract] [Full Text] [Related]

  • 14. Hepatic microRNA profiles offer predictive and mechanistic insights after exposure to genotoxic and epigenetic hepatocarcinogens.
    Koufaris C, Wright J, Currie RA, Gooderham NJ.
    Toxicol Sci; 2012 Aug 18; 128(2):532-43. PubMed ID: 22584684
    [Abstract] [Full Text] [Related]

  • 15. Deregulation of cancer-related pathways in primary hepatocytes derived from DNA repair-deficient Xpa-/-p53+/- mice upon exposure to benzo[a]pyrene.
    van Kesteren PC, Zwart PE, Pennings JL, Gottschalk WH, Kleinjans JC, van Delft JH, van Steeg H, Luijten M.
    Toxicol Sci; 2011 Sep 18; 123(1):123-32. PubMed ID: 21715664
    [Abstract] [Full Text] [Related]

  • 16. A comparison of transcriptomic and metabonomic technologies for identifying biomarkers predictive of two-year rodent cancer bioassays.
    Thomas RS, O'Connell TM, Pluta L, Wolfinger RD, Yang L, Page TJ.
    Toxicol Sci; 2007 Mar 18; 96(1):40-6. PubMed ID: 17114358
    [Abstract] [Full Text] [Related]

  • 17. Dissecting modes of action of non-genotoxic carcinogens in primary mouse hepatocytes.
    Schaap MM, Zwart EP, Wackers PF, Huijskens I, van de Water B, Breit TM, van Steeg H, Jonker MJ, Luijten M.
    Arch Toxicol; 2012 Nov 18; 86(11):1717-27. PubMed ID: 22710402
    [Abstract] [Full Text] [Related]

  • 18. Comparison of HepG2 and HepaRG by whole-genome gene expression analysis for the purpose of chemical hazard identification.
    Jennen DG, Magkoufopoulou C, Ketelslegers HB, van Herwijnen MH, Kleinjans JC, van Delft JH.
    Toxicol Sci; 2010 May 18; 115(1):66-79. PubMed ID: 20106945
    [Abstract] [Full Text] [Related]

  • 19. Evaluation of 12 mouse marker genes in rat toxicogenomics public data, Open TG-GATEs: Discrimination of genotoxic from non-genotoxic hepatocarcinogens.
    Furihata C, Suzuki T.
    Mutat Res Genet Toxicol Environ Mutagen; 2019 Feb 18; 838():9-15. PubMed ID: 30678831
    [Abstract] [Full Text] [Related]

  • 20. Cross-platform toxicogenomics for the prediction of non-genotoxic hepatocarcinogenesis in rat.
    Römer M, Eichner J, Metzger U, Templin MF, Plummer S, Ellinger-Ziegelbauer H, Zell A.
    PLoS One; 2014 Feb 18; 9(5):e97640. PubMed ID: 24830643
    [Abstract] [Full Text] [Related]

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