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236 related items for PubMed ID: 22484827

  • 1. Combined effects of a neutrophil elastase inhibitor (sivelestat sodium) and a free radical scavenger (edaravone) on lipopolysaccharide-induced acute lung injury in rats.
    Yang T, Zhang J, Sun L, Zhu X, Li J, Wang J, Chen H, Bao R, Deng X, Hou J, Liu Y.
    Inflamm Res; 2012 Jun; 61(6):563-9. PubMed ID: 22484827
    [Abstract] [Full Text] [Related]

  • 2. Improving effect of Sivelestat on lipopolysaccharide-induced lung injury in rats.
    Yuan Q, Jiang YW, Fang QH.
    APMIS; 2014 Sep; 122(9):810-7. PubMed ID: 24484066
    [Abstract] [Full Text] [Related]

  • 3. Protective effects of the free radical scavenger edaravone on acute pancreatitis-associated lung injury.
    Yang T, Mao YF, Liu SQ, Hou J, Cai ZY, Hu JY, Ni X, Deng XM, Zhu XY.
    Eur J Pharmacol; 2010 Mar 25; 630(1-3):152-7. PubMed ID: 20035747
    [Abstract] [Full Text] [Related]

  • 4. Neutrophil elastase inhibitor improves survival rate after ischemia reperfusion injury caused by supravisceral aortic clamping in rats.
    Fujimura N, Obara H, Suda K, Takeuchi H, Miyasho T, Kawasako K, Du W, Yamada S, Ono S, Matsumoto K, Matsuda S, Yagi H, Kitago M, Shinoda M, Itano O, Tanabe M, Sakamoto M, Maruyama I, Kitagawa Y.
    J Surg Res; 2013 Mar 25; 180(1):e31-6. PubMed ID: 22595015
    [Abstract] [Full Text] [Related]

  • 5. Preventive effects of edaravone, a free radical scavenger, on lipopolysaccharide-induced lung injury in mice.
    Tajima S, Soda M, Bando M, Enomoto M, Yamasawa H, Ohno S, Takada T, Suzuki E, Gejyo F, Sugiyama Y.
    Respirology; 2008 Sep 25; 13(5):646-53. PubMed ID: 18713088
    [Abstract] [Full Text] [Related]

  • 6. [Comparative study of the protective effect of Xuebijing injection and Sivelestat sodium on acute lung injury/acute respiratory distress syndrome rats].
    Tian W, Dong T.
    Zhonghua Wei Zhong Bing Ji Jiu Yi Xue; 2022 Aug 25; 34(8):837-841. PubMed ID: 36177927
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of neutrophil elastase contributes to attenuation of lipopolysaccharide-induced acute lung injury during neutropenia recovery in mice.
    Lee JM, Yeo CD, Lee HY, Rhee CK, Kim IK, Lee DG, Lee SH, Kim JW.
    J Anesth; 2017 Jun 25; 31(3):397-404. PubMed ID: 28144780
    [Abstract] [Full Text] [Related]

  • 8. Inhaled neutrophil elastase inhibitor reduces oleic acid-induced acute lung injury in rats.
    Tao W, Miao QB, Zhu YB, Shu YS.
    Pulm Pharmacol Ther; 2012 Feb 25; 25(1):99-103. PubMed ID: 22210005
    [Abstract] [Full Text] [Related]

  • 9. Effects of a synthetic protease inhibitor (gabexate mesilate) and a neutrophil elastase inhibitor (sivelestat sodium) on acid-induced lung injury in rats.
    Yoshikawa S, Tsushima K, Koizumi T, Kubo K.
    Eur J Pharmacol; 2010 Sep 01; 641(2-3):220-5. PubMed ID: 20542026
    [Abstract] [Full Text] [Related]

  • 10. Compound edaravone alleviates lipopolysaccharide (LPS)-induced acute lung injury in mice.
    Zhang Z, Luo Z, Bi A, Yang W, An W, Dong X, Chen R, Yang S, Tang H, Han X, Luo L.
    Eur J Pharmacol; 2017 Sep 15; 811():1-11. PubMed ID: 28552343
    [Abstract] [Full Text] [Related]

  • 11. Usefulness of a selective neutrophil elastase inhibitor, sivelestat, in acute lung injury patients with sepsis.
    Miyoshi S, Hamada H, Ito R, Katayama H, Irifune K, Suwaki T, Nakanishi N, Kanematsu T, Dote K, Aibiki M, Okura T, Higaki J.
    Drug Des Devel Ther; 2013 Sep 15; 7():305-16. PubMed ID: 23596346
    [Abstract] [Full Text] [Related]

  • 12. Neutrophil elastase inhibitor (sivelestat) may be a promising therapeutic option for management of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19.
    Sahebnasagh A, Saghafi F, Safdari M, Khataminia M, Sadremomtaz A, Talaei Z, Rezai Ghaleno H, Bagheri M, Habtemariam S, Avan R.
    J Clin Pharm Ther; 2020 Dec 15; 45(6):1515-1519. PubMed ID: 32860252
    [Abstract] [Full Text] [Related]

  • 13. Sivelestat sodium hydrate attenuates acute lung injury by decreasing systemic inflammation in a rat model of severe burns.
    Xiao XG, Zu HG, Li QG, Huang P.
    Eur Rev Med Pharmacol Sci; 2016 Dec 15; 20(3):528-36. PubMed ID: 26914130
    [Abstract] [Full Text] [Related]

  • 14. Suppressive effects of sivelestat on interleukin 8 and TNF-α production from LPS-stimulated granulocytes in whole blood culture.
    Shibata S, Takahashi G, Shioya N, Inada K, Endo S.
    J Anesth; 2010 Dec 15; 24(6):901-7. PubMed ID: 20976506
    [Abstract] [Full Text] [Related]

  • 15. Effect of a neutrophil elastase inhibitor on acute lung injury after cardiopulmonary bypass.
    Fujii M, Miyagi Y, Bessho R, Nitta T, Ochi M, Shimizu K.
    Interact Cardiovasc Thorac Surg; 2010 Jun 15; 10(6):859-62. PubMed ID: 20354035
    [Abstract] [Full Text] [Related]

  • 16. Role of neutrophil elastase in lung injury induced by burn-blast combined injury in rats.
    Chai JK, Cai JH, Deng HP, Zou XF, Liu W, Hu QG, Shen CA, Yin HN, Zhang XB, Chi YF, Ma L, Feng R.
    Burns; 2013 Jun 15; 39(4):745-53. PubMed ID: 22999209
    [Abstract] [Full Text] [Related]

  • 17. Protective effects of edaravone, a free radical scavenger, on lipopolysaccharide-induced acute kidney injury in a rat model of sepsis.
    Liu L, Song Y, Zhao M, Yi Z, Zeng Q.
    Int Urol Nephrol; 2015 Oct 15; 47(10):1745-52. PubMed ID: 26300162
    [Abstract] [Full Text] [Related]

  • 18. Neutrophil elastase inhibitor improves survival of rats with clinically relevant sepsis.
    Suda K, Takeuchi H, Hagiwara T, Miyasho T, Okamoto M, Kawasako K, Yamada S, Suganuma K, Wada N, Saikawa Y, Fukunaga K, Funakoshi Y, Hashimoto S, Yokota H, Maruyama I, Ishizaka A, Kitagawa Y.
    Shock; 2010 May 15; 33(5):526-31. PubMed ID: 19953005
    [Abstract] [Full Text] [Related]

  • 19. Effect of neutrophil elastase inhibitor (sivelestat sodium) in the treatment of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS): a systematic review and meta-analysis.
    Iwata K, Doi A, Ohji G, Oka H, Oba Y, Takimoto K, Igarashi W, Gremillion DH, Shimada T.
    Intern Med; 2010 May 15; 49(22):2423-32. PubMed ID: 21088343
    [Abstract] [Full Text] [Related]

  • 20. A neutrophil elastase inhibitor, sivelestat, reduces lung injury following endotoxin-induced shock in rats by inhibiting HMGB1.
    Hagiwara S, Iwasaka H, Togo K, Noguchi T.
    Inflammation; 2008 Aug 15; 31(4):227-34. PubMed ID: 18536984
    [Abstract] [Full Text] [Related]

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