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390 related items for PubMed ID: 22508831

  • 1. Cardioprotective effects mediated by angiotensin II type 1 receptor blockade and enhancing angiotensin 1-7 in experimental heart failure in angiotensin-converting enzyme 2-null mice.
    Patel VB, Bodiga S, Fan D, Das SK, Wang Z, Wang W, Basu R, Zhong J, Kassiri Z, Oudit GY.
    Hypertension; 2012 Jun; 59(6):1195-203. PubMed ID: 22508831
    [Abstract] [Full Text] [Related]

  • 2. Enhanced susceptibility to biomechanical stress in ACE2 null mice is prevented by loss of the p47(phox) NADPH oxidase subunit.
    Bodiga S, Zhong JC, Wang W, Basu R, Lo J, Liu GC, Guo D, Holland SM, Scholey JW, Penninger JM, Kassiri Z, Oudit GY.
    Cardiovasc Res; 2011 Jul 01; 91(1):151-61. PubMed ID: 21285291
    [Abstract] [Full Text] [Related]

  • 3. Loss of angiotensin-converting enzyme 2 accelerates maladaptive left ventricular remodeling in response to myocardial infarction.
    Kassiri Z, Zhong J, Guo D, Basu R, Wang X, Liu PP, Scholey JW, Penninger JM, Oudit GY.
    Circ Heart Fail; 2009 Sep 01; 2(5):446-55. PubMed ID: 19808375
    [Abstract] [Full Text] [Related]

  • 4. Angiotensin II-mediated oxidative stress and inflammation mediate the age-dependent cardiomyopathy in ACE2 null mice.
    Oudit GY, Kassiri Z, Patel MP, Chappell M, Butany J, Backx PH, Tsushima RG, Scholey JW, Khokha R, Penninger JM.
    Cardiovasc Res; 2007 Jul 01; 75(1):29-39. PubMed ID: 17499227
    [Abstract] [Full Text] [Related]

  • 5. Cardiac protective effects of irbesartan via the PPAR-gamma signaling pathway in angiotensin-converting enzyme 2-deficient mice.
    Zhang ZZ, Shang QH, Jin HY, Song B, Oudit GY, Lu L, Zhou T, Xu YL, Gao PJ, Zhu DL, Penninger JM, Zhong JC.
    J Transl Med; 2013 Sep 25; 11():229. PubMed ID: 24067190
    [Abstract] [Full Text] [Related]

  • 6. Angiotensin-converting enzyme 2 suppresses pathological hypertrophy, myocardial fibrosis, and cardiac dysfunction.
    Zhong J, Basu R, Guo D, Chow FL, Byrns S, Schuster M, Loibner H, Wang XH, Penninger JM, Kassiri Z, Oudit GY.
    Circulation; 2010 Aug 17; 122(7):717-28, 18 p following 728. PubMed ID: 20679547
    [Abstract] [Full Text] [Related]

  • 7. Deletion of angiotensin-converting enzyme 2 exacerbates renal inflammation and injury in apolipoprotein E-deficient mice through modulation of the nephrin and TNF-alpha-TNFRSF1A signaling.
    Jin HY, Chen LJ, Zhang ZZ, Xu YL, Song B, Xu R, Oudit GY, Gao PJ, Zhu DL, Zhong JC.
    J Transl Med; 2015 Aug 06; 13():255. PubMed ID: 26245758
    [Abstract] [Full Text] [Related]

  • 8. Angiotensin II induced proteolytic cleavage of myocardial ACE2 is mediated by TACE/ADAM-17: a positive feedback mechanism in the RAS.
    Patel VB, Clarke N, Wang Z, Fan D, Parajuli N, Basu R, Putko B, Kassiri Z, Turner AJ, Oudit GY.
    J Mol Cell Cardiol; 2014 Jan 06; 66():167-76. PubMed ID: 24332999
    [Abstract] [Full Text] [Related]

  • 9. Possible role of angiotensin-converting enzyme 2 and activation of angiotensin II type 2 receptor by angiotensin-(1-7) in improvement of vascular remodeling by angiotensin II type 1 receptor blockade.
    Ohshima K, Mogi M, Nakaoka H, Iwanami J, Min LJ, Kanno H, Tsukuda K, Chisaka T, Bai HY, Wang XL, Ogimoto A, Higaki J, Horiuchi M.
    Hypertension; 2014 Mar 06; 63(3):e53-9. PubMed ID: 24379178
    [Abstract] [Full Text] [Related]

  • 10. Angiotensin(1-7) blunts hypertensive cardiac remodeling by a direct effect on the heart.
    Mercure C, Yogi A, Callera GE, Aranha AB, Bader M, Ferreira AJ, Santos RA, Walther T, Touyz RM, Reudelhuber TL.
    Circ Res; 2008 Nov 21; 103(11):1319-26. PubMed ID: 18845809
    [Abstract] [Full Text] [Related]

  • 11. Role of angiotensin-converting enzyme 2/angiotensin-(1-7)/Mas axis in the hypotensive effect of azilsartan.
    Iwanami J, Mogi M, Tsukuda K, Wang XL, Nakaoka H, Ohshima K, Chisaka T, Bai HY, Kanno H, Min LJ, Horiuchi M.
    Hypertens Res; 2014 Jul 21; 37(7):616-20. PubMed ID: 24599018
    [Abstract] [Full Text] [Related]

  • 12. Prevention of angiotensin II-mediated renal oxidative stress, inflammation, and fibrosis by angiotensin-converting enzyme 2.
    Zhong J, Guo D, Chen CB, Wang W, Schuster M, Loibner H, Penninger JM, Scholey JW, Kassiri Z, Oudit GY.
    Hypertension; 2011 Feb 21; 57(2):314-22. PubMed ID: 21189404
    [Abstract] [Full Text] [Related]

  • 13. Olmesartan is an angiotensin II receptor blocker with an inhibitory effect on angiotensin-converting enzyme.
    Agata J, Ura N, Yoshida H, Shinshi Y, Sasaki H, Hyakkoku M, Taniguchi S, Shimamoto K.
    Hypertens Res; 2006 Nov 21; 29(11):865-74. PubMed ID: 17345786
    [Abstract] [Full Text] [Related]

  • 14. ACE2 Deficiency Worsens Epicardial Adipose Tissue Inflammation and Cardiac Dysfunction in Response to Diet-Induced Obesity.
    Patel VB, Mori J, McLean BA, Basu R, Das SK, Ramprasath T, Parajuli N, Penninger JM, Grant MB, Lopaschuk GD, Oudit GY.
    Diabetes; 2016 Jan 21; 65(1):85-95. PubMed ID: 26224885
    [Abstract] [Full Text] [Related]

  • 15. Olmesartan attenuates the development of heart failure after experimental autoimmune myocarditis in rats through the modulation of ANG 1-7 mas receptor.
    Sukumaran V, Veeraveedu PT, Gurusamy N, Lakshmanan AP, Yamaguchi K, Ma M, Suzuki K, Nagata M, Takagi R, Kodama M, Watanabe K.
    Mol Cell Endocrinol; 2012 Apr 04; 351(2):208-19. PubMed ID: 22200414
    [Abstract] [Full Text] [Related]

  • 16. The counterregulating role of ACE2 and ACE2-mediated angiotensin 1-7 signaling against angiotensin II stimulation in vascular cells.
    Hayashi N, Yamamoto K, Ohishi M, Tatara Y, Takeya Y, Shiota A, Oguro R, Iwamoto Y, Takeda M, Rakugi H.
    Hypertens Res; 2010 Nov 04; 33(11):1182-5. PubMed ID: 20703229
    [Abstract] [Full Text] [Related]

  • 17. ACE2 of the heart: From angiotensin I to angiotensin (1-7).
    Keidar S, Kaplan M, Gamliel-Lazarovich A.
    Cardiovasc Res; 2007 Feb 01; 73(3):463-9. PubMed ID: 17049503
    [Abstract] [Full Text] [Related]

  • 18. Combination renin-angiotensin system blockade and angiotensin-converting enzyme 2 in experimental myocardial infarction: implications for future therapeutic directions.
    Burchill LJ, Velkoska E, Dean RG, Griggs K, Patel SK, Burrell LM.
    Clin Sci (Lond); 2012 Dec 01; 123(11):649-58. PubMed ID: 22715807
    [Abstract] [Full Text] [Related]

  • 19. The effects of different angiotensin II type 1 receptor blockers on the regulation of the ACE-AngII-AT1 and ACE2-Ang(1-7)-Mas axes in pressure overload-induced cardiac remodeling in male mice.
    Wang X, Ye Y, Gong H, Wu J, Yuan J, Wang S, Yin P, Ding Z, Kang L, Jiang Q, Zhang W, Li Y, Ge J, Zou Y.
    J Mol Cell Cardiol; 2016 Aug 01; 97():180-90. PubMed ID: 27210827
    [Abstract] [Full Text] [Related]

  • 20. Candesartan cilexetil protects from cardiac myosin induced cardiotoxicity via reduction of endoplasmic reticulum stress and apoptosis in rats: involvement of ACE2-Ang (1-7)-mas axis.
    Arumugam S, Thandavarayan RA, Palaniyandi SS, Giridharan VV, Arozal W, Sari FR, Soetikno V, Harima M, Suzuki K, Kodama M, Watanabe K.
    Toxicology; 2012 Jan 27; 291(1-3):139-45. PubMed ID: 22120037
    [Abstract] [Full Text] [Related]

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