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PUBMED FOR HANDHELDS

Journal Abstract Search


90 related items for PubMed ID: 22516681

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  • 3. Cyclopamine: from cyclops lambs to cancer treatment.
    Lee ST, Welch KD, Panter KE, Gardner DR, Garrossian M, Chang CW.
    J Agric Food Chem; 2014 Jul 30; 62(30):7355-62. PubMed ID: 24754790
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  • 6. Cyclopamine bioactivity by extraction method from Veratrum californicum.
    Turner MW, Cruz R, Mattos J, Baughman N, Elwell J, Fothergill J, Nielsen A, Brookhouse J, Bartlett A, Malek P, Pu X, King MD, McDougal OM.
    Bioorg Med Chem; 2016 Aug 15; 24(16):3752-7. PubMed ID: 27338657
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  • 10. In vivo inhibition of endogenous brain tumors through systemic interference of Hedgehog signaling in mice.
    Sanchez P, Ruiz i Altaba A.
    Mech Dev; 2005 Feb 15; 122(2):223-30. PubMed ID: 15652709
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  • 14. Discovery of a potent and orally active hedgehog pathway antagonist (IPI-926).
    Tremblay MR, Lescarbeau A, Grogan MJ, Tan E, Lin G, Austad BC, Yu LC, Behnke ML, Nair SJ, Hagel M, White K, Conley J, Manna JD, Alvarez-Diez TM, Hoyt J, Woodward CN, Sydor JR, Pink M, MacDougall J, Campbell MJ, Cushing J, Ferguson J, Curtis MS, McGovern K, Read MA, Palombella VJ, Adams J, Castro AC.
    J Med Chem; 2009 Jul 23; 52(14):4400-18. PubMed ID: 19522463
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  • 15. Cyclopamine-induced synophthalmia in sheep: defining a critical window and toxicokinetic evaluation.
    Welch KD, Panter KE, Lee ST, Gardner DR, Stegelmeier BL, Cook D.
    J Appl Toxicol; 2009 Jul 23; 29(5):414-21. PubMed ID: 19301244
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  • 16. Blockade of hedgehog signaling pathway as a therapeutic strategy for pancreatic cancer.
    Xu FG, Ma QY, Wang Z.
    Cancer Lett; 2009 Oct 08; 283(2):119-24. PubMed ID: 19232458
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  • 17. Hedgehog signal activation in gastric pit cell and in diffuse-type gastric cancer.
    Fukaya M, Isohata N, Ohta H, Aoyagi K, Ochiya T, Saeki N, Yanagihara K, Nakanishi Y, Taniguchi H, Sakamoto H, Shimoda T, Nimura Y, Yoshida T, Sasaki H.
    Gastroenterology; 2006 Jul 08; 131(1):14-29. PubMed ID: 16831586
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  • 18. Modulators of the hedgehog signaling pathway.
    Heretsch P, Tzagkaroulaki L, Giannis A.
    Bioorg Med Chem; 2010 Sep 15; 18(18):6613-24. PubMed ID: 20708941
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  • 19. Semisynthetic cyclopamine analogues as potent and orally bioavailable hedgehog pathway antagonists.
    Tremblay MR, Nevalainen M, Nair SJ, Porter JR, Castro AC, Behnke ML, Yu LC, Hagel M, White K, Faia K, Grenier L, Campbell MJ, Cushing J, Woodward CN, Hoyt J, Foley MA, Read MA, Sydor JR, Tong JK, Palombella VJ, McGovern K, Adams J.
    J Med Chem; 2008 Nov 13; 51(21):6646-9. PubMed ID: 18842035
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  • 20. Hydroxylated cyclopamine analogues from Veratrum californicum and their hedgehog pathway inhibiting activity.
    Chianese G, Lopatriello A, Sirignano C, Andreani A, Gambini A, De Combarieu E, Stornaiuolo M, Taglialatela-Scafati O.
    Bioorg Med Chem; 2023 Apr 15; 84():117265. PubMed ID: 37001245
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