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313 related items for PubMed ID: 22517429

  • 1. Proteasome inhibitor interacts synergistically with autophagy inhibitor to suppress proliferation and induce apoptosis in hepatocellular carcinoma.
    Hui B, Shi YH, Ding ZB, Zhou J, Gu CY, Peng YF, Yang H, Liu WR, Shi GM, Fan J.
    Cancer; 2012 Nov 15; 118(22):5560-71. PubMed ID: 22517429
    [Abstract] [Full Text] [Related]

  • 2. An autophagy inhibitor enhances the inhibition of cell proliferation induced by a proteasome inhibitor in MCF-7 cells.
    Yao F, Wang G, Wei W, Tu Y, Tong H, Sun S.
    Mol Med Rep; 2012 Jan 15; 5(1):84-8. PubMed ID: 21931937
    [Abstract] [Full Text] [Related]

  • 3. Inhibition of autophagy induced by proteasome inhibition increases cell death in human SHG-44 glioma cells.
    Ge PF, Zhang JZ, Wang XF, Meng FK, Li WC, Luan YX, Ling F, Luo YN.
    Acta Pharmacol Sin; 2009 Jul 15; 30(7):1046-52. PubMed ID: 19575007
    [Abstract] [Full Text] [Related]

  • 4. Inhibition of autophagy enhances apoptosis induced by proteasome inhibitor bortezomib in human glioblastoma U87 and U251 cells.
    Zhang X, Li W, Wang C, Leng X, Lian S, Feng J, Li J, Wang H.
    Mol Cell Biochem; 2014 Jan 15; 385(1-2):265-75. PubMed ID: 24104452
    [Abstract] [Full Text] [Related]

  • 5. Effect of inhibition of the ubiquitin-proteasome system and Hsp90 on growth and survival of rhabdomyosarcoma cells in vitro.
    Peron M, Bonvini P, Rosolen A.
    BMC Cancer; 2012 Jun 12; 12():233. PubMed ID: 22691173
    [Abstract] [Full Text] [Related]

  • 6. Cancerous inhibitor of protein phosphatase 2A mediates bortezomib-induced autophagy in hepatocellular carcinoma independent of proteasome.
    Yu HC, Hou DR, Liu CY, Lin CS, Shiau CW, Cheng AL, Chen KF.
    PLoS One; 2013 Jun 12; 8(2):e55705. PubMed ID: 23383345
    [Abstract] [Full Text] [Related]

  • 7. Novel synergistic antitumor effects of rapamycin with bortezomib on hepatocellular carcinoma cells and orthotopic tumor model.
    Wang C, Gao D, Guo K, Kang X, Jiang K, Sun C, Li Y, Sun L, Shu H, Jin G, Sun H, Wu W, Liu Y.
    BMC Cancer; 2012 May 04; 12():166. PubMed ID: 22559167
    [Abstract] [Full Text] [Related]

  • 8. Effect of autophagy on multiple myeloma cell viability.
    Hoang B, Benavides A, Shi Y, Frost P, Lichtenstein A.
    Mol Cancer Ther; 2009 Jul 04; 8(7):1974-84. PubMed ID: 19509276
    [Abstract] [Full Text] [Related]

  • 9. Beclin 1 enhances proteasome inhibition-mediated cytotoxicity of thyroid cancer cells in macroautophagy-independent manner.
    Zhang HY, Du ZX, Meng X, Zong ZH, Wang HQ.
    J Clin Endocrinol Metab; 2013 Feb 04; 98(2):E217-26. PubMed ID: 23264393
    [Abstract] [Full Text] [Related]

  • 10. Bortezomib induces protective autophagy through AMP-activated protein kinase activation in cultured pancreatic and colorectal cancer cells.
    Min H, Xu M, Chen ZR, Zhou JD, Huang M, Zheng K, Zou XP.
    Cancer Chemother Pharmacol; 2014 Jul 04; 74(1):167-76. PubMed ID: 24842158
    [Abstract] [Full Text] [Related]

  • 11. Antitumor effects of proteasome inhibition in anaplastic thyroid carcinoma.
    Altmann A, Markert A, Askoxylakis V, Schöning T, Jesenofsky R, Eisenhut M, Haberkorn U.
    J Nucl Med; 2012 Nov 04; 53(11):1764-71. PubMed ID: 23055533
    [Abstract] [Full Text] [Related]

  • 12. Autophagy-independent enhancing effects of Beclin 1 on cytotoxicity of ovarian cancer cells mediated by proteasome inhibitors.
    Liu C, Yan X, Wang HQ, Gao YY, Liu J, Hu Z, Liu D, Gao J, Lin B.
    BMC Cancer; 2012 Dec 27; 12():622. PubMed ID: 23270461
    [Abstract] [Full Text] [Related]

  • 13. 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes induce autophagic cell death in estrogen receptor negative breast cancer.
    Vanderlaag K, Su Y, Frankel AE, Burghardt RC, Barhoumi R, Chadalapaka G, Jutooru I, Safe S.
    BMC Cancer; 2010 Dec 03; 10():669. PubMed ID: 21129193
    [Abstract] [Full Text] [Related]

  • 14. The GST-BHMT assay reveals a distinct mechanism underlying proteasome inhibition-induced macroautophagy in mammalian cells.
    Rui YN, Xu Z, Chen Z, Zhang S.
    Autophagy; 2015 Dec 03; 11(5):812-32. PubMed ID: 25984893
    [Abstract] [Full Text] [Related]

  • 15. Down-regulation of phospho-Akt is a major molecular determinant of bortezomib-induced apoptosis in hepatocellular carcinoma cells.
    Chen KF, Yeh PY, Yeh KH, Lu YS, Huang SY, Cheng AL.
    Cancer Res; 2008 Aug 15; 68(16):6698-707. PubMed ID: 18701494
    [Abstract] [Full Text] [Related]

  • 16. Bortezomib enhances cancer cell death by blocking the autophagic flux through stimulating ERK phosphorylation.
    Kao C, Chao A, Tsai CL, Chuang WC, Huang WP, Chen GC, Lin CY, Wang TH, Wang HS, Lai CH.
    Cell Death Dis; 2014 Nov 06; 5(11):e1510. PubMed ID: 25375375
    [Abstract] [Full Text] [Related]

  • 17. Cooperative cytotoxicity of proteasome inhibitors and tumor necrosis factor-related apoptosis-inducing ligand in chemoresistant Bcl-2-overexpressing cells.
    Nencioni A, Wille L, Dal Bello G, Boy D, Cirmena G, Wesselborg S, Belka C, Brossart P, Patrone F, Ballestrero A.
    Clin Cancer Res; 2005 Jun 01; 11(11):4259-65. PubMed ID: 15930365
    [Abstract] [Full Text] [Related]

  • 18. BAG3 induction is required to mitigate proteotoxicity via selective autophagy following inhibition of constitutive protein degradation pathways.
    Rapino F, Jung M, Fulda S.
    Oncogene; 2014 Mar 27; 33(13):1713-24. PubMed ID: 23644654
    [Abstract] [Full Text] [Related]

  • 19. Cytotoxic synergy between the multikinase inhibitor sorafenib and the proteasome inhibitor bortezomib in vitro: induction of apoptosis through Akt and c-Jun NH2-terminal kinase pathways.
    Yu C, Friday BB, Lai JP, Yang L, Sarkaria J, Kay NE, Carter CA, Roberts LR, Kaufmann SH, Adjei AA.
    Mol Cancer Ther; 2006 Sep 27; 5(9):2378-87. PubMed ID: 16985072
    [Abstract] [Full Text] [Related]

  • 20. Restoration of klotho expression induces apoptosis and autophagy in hepatocellular carcinoma cells.
    Shu G, Xie B, Ren F, Liu DC, Zhou J, Li Q, Chen J, Yuan L, Zhou J.
    Cell Oncol (Dordr); 2013 Apr 27; 36(2):121-9. PubMed ID: 23248036
    [Abstract] [Full Text] [Related]

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