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Journal Abstract Search

187 related items for PubMed ID: 2252901

  • 1.
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  • 2. Preferential cleavage of des-31,32-proinsulin over intact proinsulin by the insulin secretory granule type II endopeptidase. Implication of a favored route for prohormone processing.
    Rhodes CJ, Lincoln B, Shoelson SE.
    J Biol Chem; 1992 Nov 15; 267(32):22719-27. PubMed ID: 1429623
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  • 3. Predicted structural alterations in proinsulin during its interactions with prohormone convertases.
    Lipkind G, Steiner DF.
    Biochemistry; 1999 Jan 19; 38(3):890-6. PubMed ID: 9893983
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  • 5. Biochemical and clinical implications of proinsulin conversion intermediates.
    Given BD, Cohen RM, Shoelson SE, Frank BH, Rubenstein AH, Tager HS.
    J Clin Invest; 1985 Oct 19; 76(4):1398-405. PubMed ID: 3902891
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  • 6. What beta-cell defect could lead to hyperproinsulinemia in NIDDM? Some clues from recent advances made in understanding the proinsulin-processing mechanism.
    Rhodes CJ, Alarcón C.
    Diabetes; 1994 Apr 19; 43(4):511-7. PubMed ID: 8138054
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  • 7. Processing of proinsulin by furin, PC2, and PC3 in (co) transfected COS (monkey kidney) cells.
    Vollenweider F, Kaufmann J, Irminger JC, Halban PA.
    Diabetes; 1995 Sep 19; 44(9):1075-80. PubMed ID: 7657031
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  • 8. Two-dimensional NMR and photo-CIDNP studies of the insulin monomer: assignment of aromatic resonances with application to protein folding, structure, and dynamics.
    Weiss MA, Nguyen DT, Khait I, Inouye K, Frank BH, Beckage M, O'Shea E, Shoelson SE, Karplus M, Neuringer LJ.
    Biochemistry; 1989 Dec 12; 28(25):9855-73. PubMed ID: 2692717
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  • 10. Sequence requirements for proinsulin processing at the B-chain/C-peptide junction.
    Kaufmann JE, Irminger JC, Halban PA.
    Biochem J; 1995 Sep 15; 310 ( Pt 3)(Pt 3):869-74. PubMed ID: 7575420
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  • 11. Degradation of proinsulin and isolated C-peptide by rat kidney neutral metallo-endopeptidase.
    Varandani PT, Shroyer LA.
    Biochim Biophys Acta; 1981 Oct 13; 661(2):182-90. PubMed ID: 7028123
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  • 13. Solution structure of proinsulin: connecting domain flexibility and prohormone processing.
    Yang Y, Hua QX, Liu J, Shimizu EH, Choquette MH, Mackin RB, Weiss MA.
    J Biol Chem; 2010 Mar 12; 285(11):7847-51. PubMed ID: 20106974
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  • 14. Insulin secretory granule biogenesis and the proinsulin-processing endopeptidases.
    Hutton JC.
    Diabetologia; 1994 Sep 12; 37 Suppl 2():S48-56. PubMed ID: 7821740
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  • 15. Identification of the type 2 proinsulin processing endopeptidase as PC2, a member of the eukaryote subtilisin family.
    Bennett DL, Bailyes EM, Nielsen E, Guest PC, Rutherford NG, Arden SD, Hutton JC.
    J Biol Chem; 1992 Jul 25; 267(21):15229-36. PubMed ID: 1634553
    [Abstract] [Full Text] [Related]

  • 16. Intraorganellar calcium and pH control proinsulin cleavage in the pancreatic beta cell via two distinct site-specific endopeptidases.
    Davidson HW, Rhodes CJ, Hutton JC.
    Nature; 1988 May 05; 333(6168):93-6. PubMed ID: 3283564
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  • 18. Processing of mutated proinsulin with tetrabasic cleavage sites to mature insulin reflects the expression of furin in nonendocrine cell lines.
    Yanagita M, Hoshino H, Nakayama K, Takeuchi T.
    Endocrinology; 1993 Aug 05; 133(2):639-44. PubMed ID: 8344203
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