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163 related items for PubMed ID: 22531821

  • 1. Induction of carbonyl reductase 1 (CBR1) expression in human lung tissues and lung cancer cells by the cigarette smoke constituent benzo[a]pyrene.
    Kalabus JL, Cheng Q, Jamil RG, Schuetz EG, Blanco JG.
    Toxicol Lett; 2012 Jun 20; 211(3):266-73. PubMed ID: 22531821
    [Abstract] [Full Text] [Related]

  • 2. Functional characterization of the promoter of human carbonyl reductase 1 (CBR1). Role of XRE elements in mediating the induction of CBR1 by ligands of the aryl hydrocarbon receptor.
    Lakhman SS, Chen X, Gonzalez-Covarrubias V, Schuetz EG, Blanco JG.
    Mol Pharmacol; 2007 Sep 20; 72(3):734-43. PubMed ID: 17569794
    [Abstract] [Full Text] [Related]

  • 3. Genotoxic polycyclic aromatic hydrocarbon ortho-quinones generated by aldo-keto reductases induce CYP1A1 via nuclear translocation of the aryl hydrocarbon receptor.
    Burczynski ME, Penning TM.
    Cancer Res; 2000 Feb 15; 60(4):908-15. PubMed ID: 10706104
    [Abstract] [Full Text] [Related]

  • 4. Tobacco smoke induces CYP1B1 in the aerodigestive tract.
    Port JL, Yamaguchi K, Du B, De Lorenzo M, Chang M, Heerdt PM, Kopelovich L, Marcus CB, Altorki NK, Subbaramaiah K, Dannenberg AJ.
    Carcinogenesis; 2004 Nov 15; 25(11):2275-81. PubMed ID: 15297370
    [Abstract] [Full Text] [Related]

  • 5. The aryl hydrocarbon receptor suppresses cigarette-smoke-induced oxidative stress in association with dioxin response element (DRE)-independent regulation of sulfiredoxin 1.
    Sarill M, Zago M, Sheridan JA, Nair P, Matthews J, Gomez A, Roussel L, Rousseau S, Hamid Q, Eidelman DH, Baglole CJ.
    Free Radic Biol Med; 2015 Dec 15; 89():342-57. PubMed ID: 26408075
    [Abstract] [Full Text] [Related]

  • 6. Signal transduction-mediated activation of the aryl hydrocarbon receptor in rat hepatoma H4IIE cells.
    Backlund M, Johansson I, Mkrtchian S, Ingelman-Sundberg M.
    J Biol Chem; 1997 Dec 12; 272(50):31755-63. PubMed ID: 9395520
    [Abstract] [Full Text] [Related]

  • 7. Aryl hydrocarbon receptor-dependent induction of the IgA receptor FcαRI by the environmental contaminant benzo(a)pyrene in human macrophages.
    Pinel-Marie ML, Louarn L, Desmots S, Fardel O, Sparfel L.
    Toxicology; 2011 Nov 28; 290(1):89-95. PubMed ID: 21911031
    [Abstract] [Full Text] [Related]

  • 8. Down-Regulation of p23 in Normal Lung Epithelial Cells Reduces Toxicities From Exposure to Benzo[a]pyrene and Cigarette Smoke Condensate via an Aryl Hydrocarbon Receptor-Dependent Mechanism.
    Chen J, Yakkundi P, Chan WK.
    Toxicol Sci; 2019 Jan 01; 167(1):239-248. PubMed ID: 30204910
    [Abstract] [Full Text] [Related]

  • 9. Aryl hydrocarbon receptor-mediated activity of mutagenic polycyclic aromatic hydrocarbons determined using in vitro reporter gene assay.
    Machala M, Vondrácek J, Bláha L, Ciganek M, Neca JV.
    Mutat Res; 2001 Oct 18; 497(1-2):49-62. PubMed ID: 11525907
    [Abstract] [Full Text] [Related]

  • 10. Interleukin-8 induction by the environmental contaminant benzo(a)pyrene is aryl hydrocarbon receptor-dependent and leads to lung inflammation.
    Podechard N, Lecureur V, Le Ferrec E, Guenon I, Sparfel L, Gilot D, Gordon JR, Lagente V, Fardel O.
    Toxicol Lett; 2008 Mar 15; 177(2):130-7. PubMed ID: 18289803
    [Abstract] [Full Text] [Related]

  • 11. Involvement of oxidative stress and activation of aryl hydrocarbon receptor in elevation of CYP1A1 expression and activity in lung cells and tissues by arsenic: an in vitro and in vivo study.
    Wu JP, Chang LW, Yao HT, Chang H, Tsai HT, Tsai MH, Yeh TK, Lin P.
    Toxicol Sci; 2009 Feb 15; 107(2):385-93. PubMed ID: 19033395
    [Abstract] [Full Text] [Related]

  • 12. Human CYP1A1GFP expression in transgenic mice serves as a biomarker for environmental toxicant exposure.
    Operaña TN, Nguyen N, Chen S, Beaton D, Tukey RH.
    Toxicol Sci; 2007 Jan 15; 95(1):98-107. PubMed ID: 17065433
    [Abstract] [Full Text] [Related]

  • 13. A novel nonconsensus xenobiotic response element capable of mediating aryl hydrocarbon receptor-dependent gene expression.
    Huang G, Elferink CJ.
    Mol Pharmacol; 2012 Mar 15; 81(3):338-47. PubMed ID: 22113079
    [Abstract] [Full Text] [Related]

  • 14. Aryl hydrocarbon receptor- and calcium-dependent induction of the chemokine CCL1 by the environmental contaminant benzo[a]pyrene.
    N'Diaye M, Le Ferrec E, Lagadic-Gossmann D, Corre S, Gilot D, Lecureur V, Monteiro P, Rauch C, Galibert MD, Fardel O.
    J Biol Chem; 2006 Jul 21; 281(29):19906-15. PubMed ID: 16679317
    [Abstract] [Full Text] [Related]

  • 15. Benzo[a]pyrene at human blood equivalent level induces human lung epithelial cell invasion and migration via aryl hydrocarbon receptor signaling.
    Gao H, Ye G, Lin Y, Chi Y, Dong S.
    J Appl Toxicol; 2020 Aug 21; 40(8):1087-1098. PubMed ID: 32166782
    [Abstract] [Full Text] [Related]

  • 16. Aromatic hydrocarbon receptor (AhR).AhR nuclear translocator- and p53-mediated induction of the murine multidrug resistance mdr1 gene by 3-methylcholanthrene and benzo(a)pyrene in hepatoma cells.
    Mathieu MC, Lapierre I, Brault K, Raymond M.
    J Biol Chem; 2001 Feb 16; 276(7):4819-27. PubMed ID: 11096091
    [Abstract] [Full Text] [Related]

  • 17. Polycyclic aromatic hydrocarbons stimulate human CYP3A4 promoter activity via PXR.
    Luckert C, Ehlers A, Buhrke T, Seidel A, Lampen A, Hessel S.
    Toxicol Lett; 2013 Oct 24; 222(2):180-8. PubMed ID: 23845848
    [Abstract] [Full Text] [Related]

  • 18. Failure of Ah receptor to mediate induction of cytochromes P450 in the CYP1 family in the human hepatoma line SK-Hep-1.
    Roberts EA, Harper PA, Wong JM, Wang Y, Yang S.
    Arch Biochem Biophys; 2000 Dec 01; 384(1):190-8. PubMed ID: 11147830
    [Abstract] [Full Text] [Related]

  • 19. Benzo[a]pyrene Alters the Expression of Genes in A549 Lung Cancer Cells and Cancer Stem Cells.
    Bak Y, Jang HJ, Seo JH, No SH, Chae JI, Hong J, Yoon DY.
    J Microbiol Biotechnol; 2018 Mar 28; 28(3):425-431. PubMed ID: 29316740
    [Abstract] [Full Text] [Related]

  • 20. Aryl hydrocarbon receptor signaling plays a significant role in mediating benzo[a]pyrene- and cigarette smoke condensate-induced cytogenetic damage in vivo.
    Dertinger SD, Nazarenko DA, Silverstone AE, Gasiewicz TA.
    Carcinogenesis; 2001 Jan 28; 22(1):171-7. PubMed ID: 11159756
    [Abstract] [Full Text] [Related]

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