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Journal Abstract Search

690 related items for PubMed ID: 22538852

  • 21. Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2α, IRE1α, ATF6 and calmodulin kinase.
    Merlot AM, Shafie NH, Yu Y, Richardson V, Jansson PJ, Sahni S, Lane DJR, Kovacevic Z, Kalinowski DS, Richardson DR.
    Biochem Pharmacol; 2016 Jun 01; 109():27-47. PubMed ID: 27059255
    [Abstract] [Full Text] [Related]

  • 22. Farnesoid X receptor signaling activates the hepatic X-box binding protein 1 pathway in vitro and in mice.
    Liu X, Guo GL, Kong B, Hilburn DB, Hubchak SC, Park S, LeCuyer B, Hsieh A, Wang L, Fang D, Green RM.
    Hepatology; 2018 Jul 01; 68(1):304-316. PubMed ID: 29377207
    [Abstract] [Full Text] [Related]

  • 23. A novel feedback loop regulates the response to endoplasmic reticulum stress via the cooperation of cytoplasmic splicing and mRNA translation.
    Majumder M, Huang C, Snider MD, Komar AA, Tanaka J, Kaufman RJ, Krokowski D, Hatzoglou M.
    Mol Cell Biol; 2012 Mar 01; 32(5):992-1003. PubMed ID: 22215619
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  • 24. The molecular mechanisms of XBP-1 gene silencing on IRE1α-TRAF2-ASK1-JNK pathways in oral squamous cell carcinoma under endoplasmic reticulum stress.
    Chen H, Yang H, Pan L, Wang W, Liu X, Ren X, Liu Y, Liu W, Zhang Y, Jiang L, Li K, Zhang B, Wang LX.
    Biomed Pharmacother; 2016 Feb 01; 77():108-13. PubMed ID: 26796273
    [Abstract] [Full Text] [Related]

  • 25. Novel mechanism of enhancing IRE1α-XBP1 signalling via the PERK-ATF4 pathway.
    Tsuru A, Imai Y, Saito M, Kohno K.
    Sci Rep; 2016 Apr 07; 6():24217. PubMed ID: 27052593
    [Abstract] [Full Text] [Related]

  • 26. Loss of p53 enhances the function of the endoplasmic reticulum through activation of the IRE1α/XBP1 pathway.
    Namba T, Chu K, Kodama R, Byun S, Yoon KW, Hiraki M, Mandinova A, Lee SW.
    Oncotarget; 2015 Aug 21; 6(24):19990-20001. PubMed ID: 26254280
    [Abstract] [Full Text] [Related]

  • 27. The IRE1α-XBP1 pathway positively regulates parathyroid hormone (PTH)/PTH-related peptide receptor expression and is involved in pth-induced osteoclastogenesis.
    Tohmonda T, Yoda M, Mizuochi H, Morioka H, Matsumoto M, Urano F, Toyama Y, Horiuchi K.
    J Biol Chem; 2013 Jan 18; 288(3):1691-5. PubMed ID: 23235147
    [Abstract] [Full Text] [Related]

  • 28. Targeting Adaptive IRE1α Signaling and PLK2 in Multiple Myeloma: Possible Anti-Tumor Mechanisms of KIRA8 and Nilotinib.
    Yamashita Y, Morita S, Hosoi H, Kobata H, Kishimoto S, Ishibashi T, Mishima H, Kinoshita A, Backes BJ, Yoshiura KI, Papa FR, Sonoki T, Tamura S.
    Int J Mol Sci; 2020 Aug 31; 21(17):. PubMed ID: 32878237
    [Abstract] [Full Text] [Related]

  • 29. Response of myeloma to the proteasome inhibitor bortezomib is correlated with the unfolded protein response regulator XBP-1.
    Ling SC, Lau EK, Al-Shabeeb A, Nikolic A, Catalano A, Iland H, Horvath N, Ho PJ, Harrison S, Fleming S, Joshua DE, Allen JD.
    Haematologica; 2012 Jan 31; 97(1):64-72. PubMed ID: 21993678
    [Abstract] [Full Text] [Related]

  • 30. Mammalian IRE1α dynamically and functionally coalesces with stress granules.
    Liu S, Zhang X, Yao X, Wang G, Huang S, Chen P, Tang M, Cai J, Wu Z, Zhang Y, Xu R, Liu K, He K, Wang Y, Jiang L, Wang QA, Rui L, Liu J, Liu Y.
    Nat Cell Biol; 2024 Jun 31; 26(6):917-931. PubMed ID: 38714852
    [Abstract] [Full Text] [Related]

  • 31. Endoplasmic reticulum stress-induced IRE1α activation mediates cross-talk of GSK-3β and XBP-1 to regulate inflammatory cytokine production.
    Kim S, Joe Y, Kim HJ, Kim YS, Jeong SO, Pae HO, Ryter SW, Surh YJ, Chung HT.
    J Immunol; 2015 May 01; 194(9):4498-506. PubMed ID: 25821218
    [Abstract] [Full Text] [Related]

  • 32. A novel chemical, STF-083010, reverses tamoxifen-related drug resistance in breast cancer by inhibiting IRE1/XBP1.
    Ming J, Ruan S, Wang M, Ye D, Fan N, Meng Q, Tian B, Huang T.
    Oncotarget; 2015 Dec 01; 6(38):40692-703. PubMed ID: 26517687
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  • 33. IRE1α-XBP1 pathway promotes melanoma progression by regulating IL-6/STAT3 signaling.
    Chen C, Zhang X.
    J Transl Med; 2017 Feb 21; 15(1):42. PubMed ID: 28222747
    [Abstract] [Full Text] [Related]

  • 34. TNFα selectively activates the IRE1α/XBP1 endoplasmic reticulum stress pathway in human airway smooth muscle cells.
    Yap J, Chen X, Delmotte P, Sieck GC.
    Am J Physiol Lung Cell Mol Physiol; 2020 Mar 01; 318(3):L483-L493. PubMed ID: 31940218
    [Abstract] [Full Text] [Related]

  • 35. Divergent allosteric control of the IRE1α endoribonuclease using kinase inhibitors.
    Wang L, Perera BG, Hari SB, Bhhatarai B, Backes BJ, Seeliger MA, Schürer SC, Oakes SA, Papa FR, Maly DJ.
    Nat Chem Biol; 2012 Dec 01; 8(12):982-9. PubMed ID: 23086298
    [Abstract] [Full Text] [Related]

  • 36. Sphingosine Kinase 1 Protects Hepatocytes from Lipotoxicity via Down-regulation of IRE1α Protein Expression.
    Qi Y, Wang W, Chen J, Dai L, Kaczorowski D, Gao X, Xia P.
    J Biol Chem; 2015 Sep 18; 290(38):23282-90. PubMed ID: 26240153
    [Abstract] [Full Text] [Related]

  • 37. IRE1α-Dependent Decay of CReP/Ppp1r15b mRNA Increases Eukaryotic Initiation Factor 2α Phosphorylation and Suppresses Protein Synthesis.
    So JS, Cho S, Min SH, Kimball SR, Lee AH.
    Mol Cell Biol; 2015 Aug 18; 35(16):2761-70. PubMed ID: 26031337
    [Abstract] [Full Text] [Related]

  • 38. Identification of Doxorubicin as an Inhibitor of the IRE1α-XBP1 Axis of the Unfolded Protein Response.
    Jiang D, Lynch C, Medeiros BC, Liedtke M, Bam R, Tam AB, Yang Z, Alagappan M, Abidi P, Le QT, Giaccia AJ, Denko NC, Niwa M, Koong AC.
    Sci Rep; 2016 Sep 16; 6():33353. PubMed ID: 27634301
    [Abstract] [Full Text] [Related]

  • 39. Acridine Derivatives as Inhibitors of the IRE1α-XBP1 Pathway Are Cytotoxic to Human Multiple Myeloma.
    Jiang D, Tam AB, Alagappan M, Hay MP, Gupta A, Kozak MM, Solow-Cordero DE, Lum PY, Denko NC, Giaccia AJ, Le QT, Niwa M, Koong AC.
    Mol Cancer Ther; 2016 Sep 16; 15(9):2055-65. PubMed ID: 27307600
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  • 40. Sulforaphane synergistically enhances the cytotoxicity of arsenic trioxide in multiple myeloma cells via stress-mediated pathways.
    Doudican NA, Wen SY, Mazumder A, Orlow SJ.
    Oncol Rep; 2012 Nov 16; 28(5):1851-8. PubMed ID: 22922937
    [Abstract] [Full Text] [Related]

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