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164 related items for PubMed ID: 22543863
1. Exploring purine N7 interactions via atomic mutagenesis: the group I ribozyme as a case study. Forconi M, Benz-Moy T, Gleitsman KR, Ruben E, Metz C, Herschlag D. RNA; 2012 Jun; 18(6):1222-9. PubMed ID: 22543863 [Abstract] [Full Text] [Related]
2. Evidence that the guanosine substrate of the Tetrahymena ribozyme is bound in the anti conformation and that N7 contributes to binding. Lin CW, Hanna M, Szostak JW. Biochemistry; 1994 Mar 08; 33(9):2703-7. PubMed ID: 8117735 [Abstract] [Full Text] [Related]
3. Probing the role of metal ions in RNA catalysis: kinetic and thermodynamic characterization of a metal ion interaction with the 2'-moiety of the guanosine nucleophile in the Tetrahymena group I ribozyme. Shan SO, Herschlag D. Biochemistry; 1999 Aug 24; 38(34):10958-75. PubMed ID: 10460151 [Abstract] [Full Text] [Related]
4. A rearrangement of the guanosine-binding site establishes an extended network of functional interactions in the Tetrahymena group I ribozyme active site. Forconi M, Sengupta RN, Piccirilli JA, Herschlag D. Biochemistry; 2010 Mar 30; 49(12):2753-62. PubMed ID: 20175542 [Abstract] [Full Text] [Related]
5. Mechanistic investigations of a ribozyme derived from the Tetrahymena group I intron: insights into catalysis and the second step of self-splicing. Mei R, Herschlag D. Biochemistry; 1996 May 07; 35(18):5796-809. PubMed ID: 8639540 [Abstract] [Full Text] [Related]
6. Specificity from steric restrictions in the guanosine binding pocket of a group I ribozyme. Russell R, Herschlag D. RNA; 1999 Feb 07; 5(2):158-66. PubMed ID: 10024168 [Abstract] [Full Text] [Related]
7. The 2'-hydroxyl group of the guanosine nucleophile donates a functionally important hydrogen bond in the tetrahymena ribozyme reaction. Hougland JL, Sengupta RN, Dai Q, Deb SK, Piccirilli JA. Biochemistry; 2008 Jul 22; 47(29):7684-94. PubMed ID: 18572927 [Abstract] [Full Text] [Related]
8. Structure of the Tetrahymena ribozyme: base triple sandwich and metal ion at the active site. Guo F, Gooding AR, Cech TR. Mol Cell; 2004 Nov 05; 16(3):351-62. PubMed ID: 15525509 [Abstract] [Full Text] [Related]
9. Mutations at the guanosine-binding site of the Tetrahymena ribozyme also affect site-specific hydrolysis. Legault P, Herschlag D, Celander DW, Cech TR. Nucleic Acids Res; 1992 Dec 25; 20(24):6613-9. PubMed ID: 1480482 [Abstract] [Full Text] [Related]
10. Evidence for processivity and two-step binding of the RNA substrate from studies of J1/2 mutants of the Tetrahymena ribozyme. Herschlag D. Biochemistry; 1992 Feb 11; 31(5):1386-99. PubMed ID: 1736996 [Abstract] [Full Text] [Related]
11. The P5abc peripheral element facilitates preorganization of the tetrahymena group I ribozyme for catalysis. Engelhardt MA, Doherty EA, Knitt DS, Doudna JA, Herschlag D. Biochemistry; 2000 Mar 14; 39(10):2639-51. PubMed ID: 10704214 [Abstract] [Full Text] [Related]
12. Joining the two domains of a group I ribozyme to form the catalytic core. Tanner MA, Cech TR. Science; 1997 Feb 07; 275(5301):847-9. PubMed ID: 9012355 [Abstract] [Full Text] [Related]
13. A kinetic and thermodynamic framework for the Azoarcus group I ribozyme reaction. Gleitsman KR, Herschlag DH. RNA; 2014 Nov 07; 20(11):1732-46. PubMed ID: 25246656 [Abstract] [Full Text] [Related]
14. A chemical phylogeny of group I introns based upon interference mapping of a bacterial ribozyme. Strauss-Soukup JK, Strobel SA. J Mol Biol; 2000 Sep 15; 302(2):339-58. PubMed ID: 10970738 [Abstract] [Full Text] [Related]
16. Catalysis of RNA cleavage by a ribozyme derived from the group I intron of Anabaena pre-tRNA(Leu). Zaug AJ, Dávila-Aponte JA, Cech TR. Biochemistry; 1994 Dec 13; 33(49):14935-47. PubMed ID: 7527660 [Abstract] [Full Text] [Related]
18. Identifying RNA minor groove tertiary contacts by nucleotide analogue interference mapping with N2-methylguanosine. Ortoleva-Donnelly L, Kronman M, Strobel SA. Biochemistry; 1998 Sep 15; 37(37):12933-42. PubMed ID: 9737873 [Abstract] [Full Text] [Related]
19. Protonated 2'-aminoguanosine as a probe of the electrostatic environment of the active site of the Tetrahymena group I ribozyme. Shan SO, Narlikar GJ, Herschlag D. Biochemistry; 1999 Aug 24; 38(34):10976-88. PubMed ID: 10460152 [Abstract] [Full Text] [Related]