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Journal Abstract Search

572 related items for PubMed ID: 22546858

  • 1. SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice.
    Yao H, Chung S, Hwang JW, Rajendrasozhan S, Sundar IK, Dean DA, McBurney MW, Guarente L, Gu W, Rönty M, Kinnula VL, Rahman I.
    J Clin Invest; 2012 Jun; 122(6):2032-45. PubMed ID: 22546858
    [Abstract] [Full Text] [Related]

  • 2. FOXO3 Activation Prevents Cellular Senescence in Emphysema Induced by Cigarette Smoke.
    Jiang H, Xu Y, Jiang Y, Li Y.
    COPD; 2023 Dec; 20(1):80-91. PubMed ID: 36656684
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  • 3. Sirtuin 1 Activator SRT1720 Protects Against Lung Injury via Reduction of Type II Alveolar Epithelial Cells Apoptosis in Emphysema.
    Gu C, Li Y, Xu WL, Yan JP, Xia YJ, Ma YY, Chen C, Wang HJ, Tao HQ.
    COPD; 2015 Aug; 12(4):444-52. PubMed ID: 25415045
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  • 4. SIRT1/FoxO3 axis alteration leads to aberrant immune responses in bronchial epithelial cells.
    Di Vincenzo S, Heijink IH, Noordhoek JA, Cipollina C, Siena L, Bruno A, Ferraro M, Postma DS, Gjomarkaj M, Pace E.
    J Cell Mol Med; 2018 Apr; 22(4):2272-2282. PubMed ID: 29411515
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  • 5. SIRT1 protects against cigarette smoke-induced lung oxidative stress via a FOXO3-dependent mechanism.
    Yao H, Sundar IK, Ahmad T, Lerner C, Gerloff J, Friedman AE, Phipps RP, Sime PJ, McBurney MW, Guarente L, Rahman I.
    Am J Physiol Lung Cell Mol Physiol; 2014 May 01; 306(9):L816-28. PubMed ID: 24633890
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  • 6. FOXO3 deficiency leads to increased susceptibility to cigarette smoke-induced inflammation, airspace enlargement, and chronic obstructive pulmonary disease.
    Hwang JW, Rajendrasozhan S, Yao H, Chung S, Sundar IK, Huyck HL, Pryhuber GS, Kinnula VL, Rahman I.
    J Immunol; 2011 Jul 15; 187(2):987-98. PubMed ID: 21690325
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  • 8. SIRT1 redresses the imbalance of tissue inhibitor of matrix metalloproteinase-1 and matrix metalloproteinase-9 in the development of mouse emphysema and human COPD.
    Yao H, Hwang JW, Sundar IK, Friedman AE, McBurney MW, Guarente L, Gu W, Kinnula VL, Rahman I.
    Am J Physiol Lung Cell Mol Physiol; 2013 Nov 01; 305(9):L615-24. PubMed ID: 24039251
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  • 11. Redox regulation of SIRT1 in inflammation and cellular senescence.
    Hwang JW, Yao H, Caito S, Sundar IK, Rahman I.
    Free Radic Biol Med; 2013 Aug 01; 61():95-110. PubMed ID: 23542362
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  • 17. Genetic ablation of histone deacetylase 2 leads to lung cellular senescence and lymphoid follicle formation in COPD/emphysema.
    Sundar IK, Rashid K, Gerloff J, Rangel-Moreno J, Li D, Rahman I.
    FASEB J; 2018 Sep 01; 32(9):4955-4971. PubMed ID: 29630406
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  • 18. Cigarette smoke-induced autophagy impairment accelerates lung aging, COPD-emphysema exacerbations and pathogenesis.
    Vij N, Chandramani-Shivalingappa P, Van Westphal C, Hole R, Bodas M.
    Am J Physiol Cell Physiol; 2018 Jan 01; 314(1):C73-C87. PubMed ID: 27413169
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  • 19. Loss of FCHSD1 leads to amelioration of chronic obstructive pulmonary disease.
    Kawasaki T, Sugihara F, Fukushima K, Matsuki T, Nabeshima H, Machida T, Mitsui Y, Fujimura S, Sagawa R, Gaheun L, Kuniyoshi K, Tanaka H, Narazaki M, Kumanogoh A, Akira S, Satoh T.
    Proc Natl Acad Sci U S A; 2021 Jun 29; 118(26):. PubMed ID: 34168078
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  • 20. Exogenous neutrophil elastase enters bronchial epithelial cells and suppresses cigarette smoke extract-induced heme oxygenase-1 by cleaving sirtuin 1.
    Lee KH, Jeong J, Koo YJ, Jang AH, Lee CH, Yoo CG.
    J Biol Chem; 2017 Jul 14; 292(28):11970-11979. PubMed ID: 28588027
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