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Journal Abstract Search

383 related items for PubMed ID: 22549111

  • 1. MGMT inhibition restores ERα functional sensitivity to antiestrogen therapy.
    Bobustuc GC, Smith JS, Maddipatla S, Jeudy S, Limaye A, Isley B, Caparas ML, Constantino SM, Shah N, Baker CH, Srivenugopal KS, Baidas S, Konduri SD.
    Mol Med; 2012 Sep 07; 18(1):913-29. PubMed ID: 22549111
    [Abstract] [Full Text] [Related]

  • 2. Blockade of MGMT expression by O6 benzyl guanine leads to inhibition of pancreatic cancer growth and induction of apoptosis.
    Konduri SD, Ticku J, Bobustuc GC, Sutphin RM, Colon J, Isley B, Bhakat KK, Srivenugopal KS, Baker CH.
    Clin Cancer Res; 2009 Oct 01; 15(19):6087-95. PubMed ID: 19789303
    [Abstract] [Full Text] [Related]

  • 3. MGMT inhibition suppresses survivin expression in pancreatic cancer.
    Bobustuc GC, Patel A, Thompson M, Srivenugopal KS, Frick J, Weese J, Konduri SD.
    Pancreas; 2015 May 01; 44(4):626-35. PubMed ID: 25875800
    [Abstract] [Full Text] [Related]

  • 4. Acridine-O6-benzylguanine hybrids: Synthesis, DNA binding, MGMT inhibition and antiproliferative activity.
    Franco Pinto J, Fillion A, Duchambon P, Bombard S, Granzhan A.
    Eur J Med Chem; 2022 Jan 05; 227():113909. PubMed ID: 34731767
    [Abstract] [Full Text] [Related]

  • 5. Loss of Rho GDIα and resistance to tamoxifen via effects on estrogen receptor α.
    Barone I, Brusco L, Gu G, Selever J, Beyer A, Covington KR, Tsimelzon A, Wang T, Hilsenbeck SG, Chamness GC, Andò S, Fuqua SA.
    J Natl Cancer Inst; 2011 Apr 06; 103(7):538-52. PubMed ID: 21447808
    [Abstract] [Full Text] [Related]

  • 6. Apigenin inhibits antiestrogen-resistant breast cancer cell growth through estrogen receptor-alpha-dependent and estrogen receptor-alpha-independent mechanisms.
    Long X, Fan M, Bigsby RM, Nephew KP.
    Mol Cancer Ther; 2008 Jul 06; 7(7):2096-108. PubMed ID: 18645020
    [Abstract] [Full Text] [Related]

  • 7. Wilms' tumor 1 suppressor gene mediates antiestrogen resistance via down-regulation of estrogen receptor-alpha expression in breast cancer cells.
    Han Y, Yang L, Suarez-Saiz F, San-Marina S, Cui J, Minden MD.
    Mol Cancer Res; 2008 Aug 06; 6(8):1347-55. PubMed ID: 18708366
    [Abstract] [Full Text] [Related]

  • 8. Annonacin induces cell cycle-dependent growth arrest and apoptosis in estrogen receptor-α-related pathways in MCF-7 cells.
    Ko YM, Wu TY, Wu YC, Chang FR, Guh JY, Chuang LY.
    J Ethnopharmacol; 2011 Oct 11; 137(3):1283-90. PubMed ID: 21840388
    [Abstract] [Full Text] [Related]

  • 9. Targeting methylguanine-DNA methyltransferase in the treatment of neuroblastoma.
    Wagner LM, McLendon RE, Yoon KJ, Weiss BD, Billups CA, Danks MK.
    Clin Cancer Res; 2007 Sep 15; 13(18 Pt 1):5418-25. PubMed ID: 17875772
    [Abstract] [Full Text] [Related]

  • 10. A suppressive role of guanine nucleotide-binding protein subunit beta-4 inhibited by DNA methylation in the growth of anti-estrogen resistant breast cancer cells.
    Wang B, Li D, Rodriguez-Juarez R, Farfus A, Storozynsky Q, Malach M, Carpenter E, Filkowski J, Lykkesfeldt AE, Kovalchuk O.
    BMC Cancer; 2018 Aug 13; 18(1):817. PubMed ID: 30103729
    [Abstract] [Full Text] [Related]

  • 11. MGMT repletion after treatment of glioblastoma cells with temozolomide and O6-benzylguanine implicates NFκB and mutant p53.
    Vlachostergios PJ, Hatzidaki E, Papandreou CN.
    Neurol Res; 2013 Oct 13; 35(8):879-82. PubMed ID: 23561593
    [Abstract] [Full Text] [Related]

  • 12. Nogo-B receptor increases the resistance to tamoxifen in estrogen receptor-positive breast cancer cells.
    Gao P, Wang X, Jin Y, Hu W, Duan Y, Shi A, Du Y, Song D, Yang M, Li S, Han B, Zhao G, Zhang H, Fan Z, Miao QR.
    Breast Cancer Res; 2018 Sep 12; 20(1):112. PubMed ID: 30208932
    [Abstract] [Full Text] [Related]

  • 13. Endocrine therapy resistance can be associated with high estrogen receptor alpha (ERalpha) expression and reduced ERalpha phosphorylation in breast cancer models.
    Kuske B, Naughton C, Moore K, Macleod KG, Miller WR, Clarke R, Langdon SP, Cameron DA.
    Endocr Relat Cancer; 2006 Dec 12; 13(4):1121-33. PubMed ID: 17158758
    [Abstract] [Full Text] [Related]

  • 14. Hydroxychloroquine inhibits autophagy to potentiate antiestrogen responsiveness in ER+ breast cancer.
    Cook KL, Wärri A, Soto-Pantoja DR, Clarke PA, Cruz MI, Zwart A, Clarke R.
    Clin Cancer Res; 2014 Jun 15; 20(12):3222-32. PubMed ID: 24928945
    [Abstract] [Full Text] [Related]

  • 15. Oldenlandia diffusa extracts exert antiproliferative and apoptotic effects on human breast cancer cells through ERα/Sp1-mediated p53 activation.
    Gu G, Barone I, Gelsomino L, Giordano C, Bonofiglio D, Statti G, Menichini F, Catalano S, Andò S.
    J Cell Physiol; 2012 Oct 15; 227(10):3363-72. PubMed ID: 22213398
    [Abstract] [Full Text] [Related]

  • 16. MGMT-inhibitor in combination with TGF-βRI inhibitor or CDK 4/6 inhibitor increases temozolomide sensitivity in temozolomide-resistant glioblastoma cells.
    Das A, Henderson FC, Alshareef M, Porto GBF, Kanginakudru I, Infinger LK, Vandergrift WA, Lindhorst SM, Varma AK, Patel SJ, Cachia D.
    Clin Transl Oncol; 2021 Mar 15; 23(3):612-619. PubMed ID: 32710211
    [Abstract] [Full Text] [Related]

  • 17. Tamoxifen Resistance in Breast Cancer Is Regulated by the EZH2-ERα-GREB1 Transcriptional Axis.
    Wu Y, Zhang Z, Cenciarini ME, Proietti CJ, Amasino M, Hong T, Yang M, Liao Y, Chiang HC, Kaklamani VG, Jeselsohn R, Vadlamudi RK, Huang TH, Li R, De Angelis C, Fu X, Elizalde PV, Schiff R, Brown M, Xu K.
    Cancer Res; 2018 Feb 01; 78(3):671-684. PubMed ID: 29212856
    [Abstract] [Full Text] [Related]

  • 18. Mechanisms of estrogen receptor antagonism toward p53 and its implications in breast cancer therapeutic response and stem cell regulation.
    Konduri SD, Medisetty R, Liu W, Kaipparettu BA, Srivastava P, Brauch H, Fritz P, Swetzig WM, Gardner AE, Khan SA, Das GM.
    Proc Natl Acad Sci U S A; 2010 Aug 24; 107(34):15081-6. PubMed ID: 20696891
    [Abstract] [Full Text] [Related]

  • 19. Association between Pak1 expression and subcellular localization and tamoxifen resistance in breast cancer patients.
    Holm C, Rayala S, Jirström K, Stål O, Kumar R, Landberg G.
    J Natl Cancer Inst; 2006 May 17; 98(10):671-80. PubMed ID: 16705121
    [Abstract] [Full Text] [Related]

  • 20. HOXB13 mediates tamoxifen resistance and invasiveness in human breast cancer by suppressing ERα and inducing IL-6 expression.
    Shah N, Jin K, Cruz LA, Park S, Sadik H, Cho S, Goswami CP, Nakshatri H, Gupta R, Chang HY, Zhang Z, Cimino-Mathews A, Cope L, Umbricht C, Sukumar S.
    Cancer Res; 2013 Sep 01; 73(17):5449-58. PubMed ID: 23832664
    [Abstract] [Full Text] [Related]

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