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394 related items for PubMed ID: 22561406

  • 1. The protective effects of tanshinone IIA on neurotoxicity induced by β-amyloid protein through calpain and the p35/Cdk5 pathway in primary cortical neurons.
    Shi LL, Yang WN, Chen XL, Zhang JS, Yang PB, Hu XD, Han H, Qian YH, Liu Y.
    Neurochem Int; 2012 Jul; 61(2):227-35. PubMed ID: 22561406
    [Abstract] [Full Text] [Related]

  • 2. Involvement of calpain and p25 of CDK5 pathway in ginsenoside Rb1's attenuation of beta-amyloid peptide25-35-induced tau hyperphosphorylation in cortical neurons.
    Chen X, Huang T, Zhang J, Song J, Chen L, Zhu Y.
    Brain Res; 2008 Mar 20; 1200():99-106. PubMed ID: 18289510
    [Abstract] [Full Text] [Related]

  • 3. The protective effects of tanshinone IIA on β-amyloid protein (1-42)-induced cytotoxicity via activation of the Bcl-xL pathway in neuron.
    Qian YH, Xiao Q, Xu J.
    Brain Res Bull; 2012 Jul 01; 88(4):354-8. PubMed ID: 22498308
    [Abstract] [Full Text] [Related]

  • 4. Fuzhisan, a Chinese herbal medicine, inhibits beta-amyloid-induced neurotoxicity and tau phosphorylation through calpain/Cdk5 pathway in cultured cortical neurons.
    Zhang Z, Zhao R, Tang Y, Wen S, Wang D, Qi J.
    Neurochem Res; 2011 May 01; 36(5):801-11. PubMed ID: 21243427
    [Abstract] [Full Text] [Related]

  • 5. Stabilization of the cyclin-dependent kinase 5 activator, p35, by paclitaxel decreases beta-amyloid toxicity in cortical neurons.
    Li G, Faibushevich A, Turunen BJ, Yoon SO, Georg G, Michaelis ML, Dobrowsky RT.
    J Neurochem; 2003 Jan 01; 84(2):347-62. PubMed ID: 12558997
    [Abstract] [Full Text] [Related]

  • 6. Atorvastatin prevents Aβ oligomer-induced neurotoxicity in cultured rat hippocampal neurons by inhibiting Tau cleavage.
    Sui HJ, Zhang LL, Liu Z, Jin Y.
    Acta Pharmacol Sin; 2015 May 01; 36(5):553-64. PubMed ID: 25891085
    [Abstract] [Full Text] [Related]

  • 7. p35/Cdk5 pathway mediates soluble amyloid-beta peptide-induced tau phosphorylation in vitro.
    Town T, Zolton J, Shaffner R, Schnell B, Crescentini R, Wu Y, Zeng J, DelleDonne A, Obregon D, Tan J, Mullan M.
    J Neurosci Res; 2002 Aug 01; 69(3):362-72. PubMed ID: 12125077
    [Abstract] [Full Text] [Related]

  • 8. Neurotoxicity induces cleavage of p35 to p25 by calpain.
    Lee MS, Kwon YT, Li M, Peng J, Friedlander RM, Tsai LH.
    Nature; 2000 May 18; 405(6784):360-4. PubMed ID: 10830966
    [Abstract] [Full Text] [Related]

  • 9. The neuroprotective effects of tanshinone IIA on β-amyloid-induced toxicity in rat cortical neurons.
    Liu T, Jin H, Sun QR, Xu JH, Hu HT.
    Neuropharmacology; 2010 Dec 18; 59(7-8):595-604. PubMed ID: 20800073
    [Abstract] [Full Text] [Related]

  • 10. N-acetylcysteine prevents beta-amyloid toxicity by a stimulatory effect on p35/cyclin-dependent kinase 5 activity in cultured cortical neurons.
    Hsiao YH, Chen PS, Yeh SH, Lin CH, Gean PW.
    J Neurosci Res; 2008 Sep 18; 86(12):2685-95. PubMed ID: 18512759
    [Abstract] [Full Text] [Related]

  • 11. Neuroprotective effect of TNFalpha against the beta-amyloid neurotoxicity mediated by CDK5 kinase.
    Orellana DI, Quintanilla RA, Maccioni RB.
    Biochim Biophys Acta; 2007 Feb 18; 1773(2):254-63. PubMed ID: 17150266
    [Abstract] [Full Text] [Related]

  • 12. Processing of cdk5 activator p35 to its truncated form (p25) by calpain in acutely injured neuronal cells.
    Nath R, Davis M, Probert AW, Kupina NC, Ren X, Schielke GP, Wang KK.
    Biochem Biophys Res Commun; 2000 Jul 21; 274(1):16-21. PubMed ID: 10903889
    [Abstract] [Full Text] [Related]

  • 13. p35/Cyclin-dependent kinase 5 is required for protection against beta-amyloid-induced cell death but not tau phosphorylation by ceramide.
    Seyb KI, Ansar S, Li G, Bean J, Michaelis ML, Dobrowsky RT.
    J Mol Neurosci; 2007 Jul 21; 31(1):23-35. PubMed ID: 17416967
    [Abstract] [Full Text] [Related]

  • 14. [Effect of tanshinone IIA on the change of calcium current induced by beta-amyloid protein 25-35 in neurons of nucleus basalis of Meynert].
    Zhu S, Qian Y, Shi L, Yang W, Feng X, Li C, Liu Y.
    Zhong Nan Da Xue Xue Bao Yi Xue Ban; 2010 Aug 21; 35(8):840-6. PubMed ID: 20818077
    [Abstract] [Full Text] [Related]

  • 15. Role of calpain and caspase in beta-amyloid-induced cell death in rat primary septal cultured neurons.
    Wei Z, Song MS, MacTavish D, Jhamandas JH, Kar S.
    Neuropharmacology; 2008 Mar 21; 54(4):721-33. PubMed ID: 18222494
    [Abstract] [Full Text] [Related]

  • 16. The regulation of cyclin-dependent kinase 5 activity through the metabolism of p35 or p39 Cdk5 activator.
    Hisanaga S, Saito T.
    Neurosignals; 2003 Mar 21; 12(4-5):221-9. PubMed ID: 14673209
    [Abstract] [Full Text] [Related]

  • 17. Activation of Cdk5/p25 and tau phosphorylation following chronic brain hypoperfusion in rats involves microRNA-195 down-regulation.
    Sun LH, Ban T, Liu CD, Chen QX, Wang X, Yan ML, Hu XL, Su XL, Bao YN, Sun LL, Zhao LJ, Pei SC, Jiang XM, Zong DK, Ai J.
    J Neurochem; 2015 Sep 21; 134(6):1139-51. PubMed ID: 26118667
    [Abstract] [Full Text] [Related]

  • 18. Calpain-2/p35-p25/Cdk5 pathway is involved in the neuronal apoptosis induced by polybrominated diphenyl ether-153.
    Zhang H, Chang L, Zhang H, Nie J, Zhang Z, Yang X, Vuong AM, Wang Z, Chen A, Niu Q.
    Toxicol Lett; 2017 Aug 05; 277():41-53. PubMed ID: 28559121
    [Abstract] [Full Text] [Related]

  • 19. Caspase-3- and calpain-mediated tau cleavage are differentially prevented by estrogen and testosterone in beta-amyloid-treated hippocampal neurons.
    Park SY, Tournell C, Sinjoanu RC, Ferreira A.
    Neuroscience; 2007 Jan 05; 144(1):119-27. PubMed ID: 17055174
    [Abstract] [Full Text] [Related]

  • 20. Chronic stimulation of GABAA receptor with muscimol reduces amyloid beta protein (25-35)-induced neurotoxicity in cultured rat cortical cells.
    Lee BY, Ban JY, Seong YH.
    Neurosci Res; 2005 Aug 05; 52(4):347-56. PubMed ID: 15896866
    [Abstract] [Full Text] [Related]

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