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834 related items for PubMed ID: 22589537

  • 21. Genistein induces G2/M cell cycle arrest and apoptosis of human ovarian cancer cells via activation of DNA damage checkpoint pathways.
    Ouyang G, Yao L, Ruan K, Song G, Mao Y, Bao S.
    Cell Biol Int; 2009 Dec; 33(12):1237-44. PubMed ID: 19732843
    [Abstract] [Full Text] [Related]

  • 22. Artemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint response.
    Zhang X, Succi J, Feng Z, Prithivirajsingh S, Story MD, Legerski RJ.
    Mol Cell Biol; 2004 Oct; 24(20):9207-20. PubMed ID: 15456891
    [Abstract] [Full Text] [Related]

  • 23. Bleomycin-induced over-replication involves sustained inhibition of mitotic entry through the ATM/ATR pathway.
    Nakayama Y, Igarashi A, Kikuchi I, Obata Y, Fukumoto Y, Yamaguchi N.
    Exp Cell Res; 2009 Sep 10; 315(15):2515-28. PubMed ID: 19527713
    [Abstract] [Full Text] [Related]

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  • 25. Tachpyridine, a metal chelator, induces G2 cell-cycle arrest, activates checkpoint kinases, and sensitizes cells to ionizing radiation.
    Turner J, Koumenis C, Kute TE, Planalp RP, Brechbiel MW, Beardsley D, Cody B, Brown KD, Torti FM, Torti SV.
    Blood; 2005 Nov 01; 106(9):3191-9. PubMed ID: 16014567
    [Abstract] [Full Text] [Related]

  • 26. Naphthalimides induce G(2) arrest through the ATM-activated Chk2-executed pathway in HCT116 cells.
    Zhu H, Miao ZH, Huang M, Feng JM, Zhang ZX, Lu JJ, Cai YJ, Tong LJ, Xu YF, Qian XH, Ding J.
    Neoplasia; 2009 Nov 01; 11(11):1226-34. PubMed ID: 19881958
    [Abstract] [Full Text] [Related]

  • 27. Irradiation-induced G2/M checkpoint response requires ERK1/2 activation.
    Yan Y, Black CP, Cowan KH.
    Oncogene; 2007 Jul 12; 26(32):4689-98. PubMed ID: 17297454
    [Abstract] [Full Text] [Related]

  • 28. Gallic acid causes inactivating phosphorylation of cdc25A/cdc25C-cdc2 via ATM-Chk2 activation, leading to cell cycle arrest, and induces apoptosis in human prostate carcinoma DU145 cells.
    Agarwal C, Tyagi A, Agarwal R.
    Mol Cancer Ther; 2006 Dec 12; 5(12):3294-302. PubMed ID: 17172433
    [Abstract] [Full Text] [Related]

  • 29. Mitotic DNA damage response: Polo-like kinase-1 is dephosphorylated through ATM-Chk1 pathway.
    Lee HJ, Hwang HI, Jang YJ.
    Cell Cycle; 2010 Jun 15; 9(12):2389-98. PubMed ID: 20581453
    [Abstract] [Full Text] [Related]

  • 30. The cell cycle checkpoint kinase Chk2 is a negative regulator of mitotic catastrophe.
    Castedo M, Perfettini JL, Roumier T, Yakushijin K, Horne D, Medema R, Kroemer G.
    Oncogene; 2004 May 27; 23(25):4353-61. PubMed ID: 15048074
    [Abstract] [Full Text] [Related]

  • 31. Genistein arrests hepatoma cells at G2/M phase: involvement of ATM activation and upregulation of p21waf1/cip1 and Wee1.
    Chang KL, Kung ML, Chow NH, Su SJ.
    Biochem Pharmacol; 2004 Feb 15; 67(4):717-26. PubMed ID: 14757171
    [Abstract] [Full Text] [Related]

  • 32. Bortezomib induces G2-M arrest in human colon cancer cells through ROS-inducible phosphorylation of ATM-CHK1.
    Hong YS, Hong SW, Kim SM, Jin DH, Shin JS, Yoon DH, Kim KP, Lee JL, Heo DS, Lee JS, Kim TW.
    Int J Oncol; 2012 Jul 15; 41(1):76-82. PubMed ID: 22552540
    [Abstract] [Full Text] [Related]

  • 33. Mammalian TIMELESS is required for ATM-dependent CHK2 activation and G2/M checkpoint control.
    Yang X, Wood PA, Hrushesky WJ.
    J Biol Chem; 2010 Jan 29; 285(5):3030-4. PubMed ID: 19996108
    [Abstract] [Full Text] [Related]

  • 34. Starvation-induced activation of ATM/Chk2/p53 signaling sensitizes cancer cells to cisplatin.
    Shi Y, Felley-Bosco E, Marti TM, Orlowski K, Pruschy M, Stahel RA.
    BMC Cancer; 2012 Dec 04; 12():571. PubMed ID: 23211021
    [Abstract] [Full Text] [Related]

  • 35. Chk1 and Wee1 control genotoxic-stress induced G2-M arrest in melanoma cells.
    Vera J, Raatz Y, Wolkenhauer O, Kottek T, Bhattacharya A, Simon JC, Kunz M.
    Cell Signal; 2015 May 04; 27(5):951-60. PubMed ID: 25683911
    [Abstract] [Full Text] [Related]

  • 36. Jaceosidin, isolated from dietary mugwort (Artemisia princeps), induces G2/M cell cycle arrest by inactivating cdc25C-cdc2 via ATM-Chk1/2 activation.
    Lee JG, Kim JH, Ahn JH, Lee KT, Baek NI, Choi JH.
    Food Chem Toxicol; 2013 May 04; 55():214-21. PubMed ID: 23274058
    [Abstract] [Full Text] [Related]

  • 37. DNA damage during the spindle-assembly checkpoint degrades CDC25A, inhibits cyclin-CDC2 complexes, and reverses cells to interphase.
    Chow JP, Siu WY, Fung TK, Chan WM, Lau A, Arooz T, Ng CP, Yamashita K, Poon RY.
    Mol Biol Cell; 2003 Oct 04; 14(10):3989-4002. PubMed ID: 14517313
    [Abstract] [Full Text] [Related]

  • 38. Ataxia-telangiectasia and Rad3-related and DNA-dependent protein kinase cooperate in G2 checkpoint activation by the DNA strand-breaking nucleoside analogue 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine.
    Liu X, Matsuda A, Plunkett W.
    Mol Cancer Ther; 2008 Jan 04; 7(1):133-42. PubMed ID: 18202016
    [Abstract] [Full Text] [Related]

  • 39. Kotomolide A arrests cell cycle progression and induces apoptosis through the induction of ATM/p53 and the initiation of mitochondrial system in human non-small cell lung cancer A549 cells.
    Chen CY, Hsu YL, Tsai YC, Kuo PL.
    Food Chem Toxicol; 2008 Jul 04; 46(7):2476-84. PubMed ID: 18511169
    [Abstract] [Full Text] [Related]

  • 40. Knockdown of Chk1 sensitizes human colon carcinoma HCT116 cells in a p53-dependent manner to lidamycin through abrogation of a G2/M checkpoint and induction of apoptosis.
    Pan Y, Ren KH, He HW, Shao RG.
    Cancer Biol Ther; 2009 Aug 04; 8(16):1559-66. PubMed ID: 19502782
    [Abstract] [Full Text] [Related]

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