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325 related items for PubMed ID: 22622028

  • 1. Alpha-melanocyte-stimulating hormone suppresses oxidative stress through a p53-mediated signaling pathway in human melanocytes.
    Kadekaro AL, Chen J, Yang J, Chen S, Jameson J, Swope VB, Cheng T, Kadakia M, Abdel-Malek Z.
    Mol Cancer Res; 2012 Jun; 10(6):778-86. PubMed ID: 22622028
    [Abstract] [Full Text] [Related]

  • 2. MC1R variant allele effects on UVR-induced phosphorylation of p38, p53, and DDB2 repair protein responses in melanocytic cells in culture.
    Wong SS, Ainger SA, Leonard JH, Sturm RA.
    J Invest Dermatol; 2012 May; 132(5):1452-61. PubMed ID: 22336944
    [Abstract] [Full Text] [Related]

  • 3. Endothelin-1 and α-melanocortin have redundant effects on global genome repair in UV-irradiated human melanocytes despite distinct signaling pathways.
    Swope VB, Starner RJ, Rauck C, Abdel-Malek ZA.
    Pigment Cell Melanoma Res; 2020 Mar; 33(2):293-304. PubMed ID: 31505093
    [Abstract] [Full Text] [Related]

  • 4. MC1R: Front and Center in the Bright Side of Dark Eumelanin and DNA Repair.
    Swope VB, Abdel-Malek ZA.
    Int J Mol Sci; 2018 Sep 08; 19(9):. PubMed ID: 30205559
    [Abstract] [Full Text] [Related]

  • 5. Melanoma-associated melanocortin 1 receptor variants confer redox signaling-dependent protection against oxidative DNA damage.
    Castejón-Griñán M, Cerdido S, Sánchez-Beltrán J, Lambertos A, Abrisqueta M, Herraiz C, Jiménez-Cervantes C, García-Borrón JC.
    Redox Biol; 2024 Jun 08; 72():103135. PubMed ID: 38565069
    [Abstract] [Full Text] [Related]

  • 6. Significance of the melanocortin 1 receptor in the DNA damage response of human melanocytes to ultraviolet radiation.
    Swope V, Alexander C, Starner R, Schwemberger S, Babcock G, Abdel-Malek ZA.
    Pigment Cell Melanoma Res; 2014 Jul 08; 27(4):601-10. PubMed ID: 24730569
    [Abstract] [Full Text] [Related]

  • 7. alpha-MSH activates immediate defense responses to UV-induced oxidative stress in human melanocytes.
    Song X, Mosby N, Yang J, Xu A, Abdel-Malek Z, Kadekaro AL.
    Pigment Cell Melanoma Res; 2009 Dec 08; 22(6):809-18. PubMed ID: 19659742
    [Abstract] [Full Text] [Related]

  • 8. MC1R expression in HaCaT keratinocytes inhibits UVA-induced ROS production via NADPH oxidase- and cAMP-dependent mechanisms.
    Henri P, Beaumel S, Guezennec A, Poumès C, Stoebner PE, Stasia MJ, Guesnet J, Martinez J, Meunier L.
    J Cell Physiol; 2012 Jun 08; 227(6):2578-85. PubMed ID: 21898403
    [Abstract] [Full Text] [Related]

  • 9. Divergence of cAMP signalling pathways mediating augmented nucleotide excision repair and pigment induction in melanocytes.
    Wolf Horrell EM, Jarrett SG, Carter KM, D'Orazio JA.
    Exp Dermatol; 2017 Jul 08; 26(7):577-584. PubMed ID: 28094871
    [Abstract] [Full Text] [Related]

  • 10. alpha-MSH tripeptide analogs activate the melanocortin 1 receptor and reduce UV-induced DNA damage in human melanocytes.
    Abdel-Malek ZA, Ruwe A, Kavanagh-Starner R, Kadekaro AL, Swope V, Haskell-Luevano C, Koikov L, Knittel JJ.
    Pigment Cell Melanoma Res; 2009 Oct 08; 22(5):635-44. PubMed ID: 19558415
    [Abstract] [Full Text] [Related]

  • 11. Alpha-melanocyte stimulating hormone protects retinal pigment epithelium cells from oxidative stress through activation of melanocortin 1 receptor-Akt-mTOR signaling.
    Cheng LB, Cheng L, Bi HE, Zhang ZQ, Yao J, Zhou XZ, Jiang Q.
    Biochem Biophys Res Commun; 2014 Jan 10; 443(2):447-52. PubMed ID: 24316214
    [Abstract] [Full Text] [Related]

  • 12. Melanoma prevention strategy based on using tetrapeptide alpha-MSH analogs that protect human melanocytes from UV-induced DNA damage and cytotoxicity.
    Abdel-Malek ZA, Kadekaro AL, Kavanagh RJ, Todorovic A, Koikov LN, McNulty JC, Jackson PJ, Millhauser GL, Schwemberger S, Babcock G, Haskell-Luevano C, Knittel JJ.
    FASEB J; 2006 Jul 10; 20(9):1561-3. PubMed ID: 16723376
    [Abstract] [Full Text] [Related]

  • 13. The melanocortin 1 receptor and the UV response of human melanocytes--a shift in paradigm.
    Abdel-Malek ZA, Knittel J, Kadekaro AL, Swope VB, Starner R.
    Photochem Photobiol; 2008 Jul 10; 84(2):501-8. PubMed ID: 18282187
    [Abstract] [Full Text] [Related]

  • 14. Signaling from the human melanocortin 1 receptor to ERK1 and ERK2 mitogen-activated protein kinases involves transactivation of cKIT.
    Herraiz C, Journé F, Abdel-Malek Z, Ghanem G, Jiménez-Cervantes C, García-Borrón JC.
    Mol Endocrinol; 2011 Jan 10; 25(1):138-56. PubMed ID: 21084381
    [Abstract] [Full Text] [Related]

  • 15. Melanocortins and the melanocortin 1 receptor, moving translationally towards melanoma prevention.
    Abdel-Malek ZA, Swope VB, Starner RJ, Koikov L, Cassidy P, Leachman S.
    Arch Biochem Biophys; 2014 Dec 01; 563():4-12. PubMed ID: 25017567
    [Abstract] [Full Text] [Related]

  • 16. Novel approaches to vitiligo treatment via modulation of mTOR and NF-κB pathways in human skin melanocytes.
    Wan J, Lin F, Zhang W, Xu A, DeGiorgis J, Lu H, Wan Y.
    Int J Biol Sci; 2017 Dec 01; 13(3):391-400. PubMed ID: 28367103
    [Abstract] [Full Text] [Related]

  • 17. IDH2 deficiency accelerates skin pigmentation in mice via enhancing melanogenesis.
    Park JH, Ku HJ, Lee JH, Park JW.
    Redox Biol; 2018 Jul 01; 17():16-24. PubMed ID: 29660504
    [Abstract] [Full Text] [Related]

  • 18. Defining MC1R regulation in human melanocytes by its agonist α-melanocortin and antagonists agouti signaling protein and β-defensin 3.
    Swope VB, Jameson JA, McFarland KL, Supp DM, Miller WE, McGraw DW, Patel MA, Nix MA, Millhauser GL, Babcock GF, Abdel-Malek ZA.
    J Invest Dermatol; 2012 Sep 01; 132(9):2255-62. PubMed ID: 22572817
    [Abstract] [Full Text] [Related]

  • 19. Activation of the Melanocortin-1 Receptor by NDP-MSH Attenuates Oxidative Stress and Neuronal Apoptosis through PI3K/Akt/Nrf2 Pathway after Intracerebral Hemorrhage in Mice.
    Fu S, Luo X, Wu X, Zhang T, Gu L, Wang Y, Gao M, Cheng Y, Xie Z.
    Oxid Med Cell Longev; 2020 Sep 01; 2020():8864100. PubMed ID: 33274009
    [Abstract] [Full Text] [Related]

  • 20. The α-melanocyte-stimulating hormone/melanocortin-1 receptor interaction: A driver of pleiotropic effects beyond pigmentation.
    Herraiz C, Martínez-Vicente I, Maresca V.
    Pigment Cell Melanoma Res; 2021 Jul 01; 34(4):748-761. PubMed ID: 33884776
    [Abstract] [Full Text] [Related]

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