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492 related items for PubMed ID: 22623136
1. A universal surrogate peptide to enable LC-MS/MS bioanalysis of a diversity of human monoclonal antibody and human Fc-fusion protein drug candidates in pre-clinical animal studies. Furlong MT, Ouyang Z, Wu S, Tamura J, Olah T, Tymiak A, Jemal M. Biomed Chromatogr; 2012 Aug; 26(8):1024-32. PubMed ID: 22623136 [Abstract] [Full Text] [Related]
2. Dual universal peptide approach to bioanalysis of human monoclonal antibody protein drug candidates in animal studies. Furlong MT, Zhao S, Mylott W, Jenkins R, Gao M, Hegde V, Tamura J, Tymiak A, Jemal M. Bioanalysis; 2013 Jun; 5(11):1363-76. PubMed ID: 23742306 [Abstract] [Full Text] [Related]
3. Liquid chromatography coupled with tandem mass spectrometry for the bioanalysis of proteins in drug development: practical considerations in assay development and validation. Liu G, Ji QC, Dodge R, Sun H, Shuster D, Zhao Q, Arnold M. J Chromatogr A; 2013 Apr 05; 1284():155-62. PubMed ID: 23466204 [Abstract] [Full Text] [Related]
6. In vivo deamidation characterization of monoclonal antibody by LC/MS/MS. Huang L, Lu J, Wroblewski VJ, Beals JM, Riggin RM. Anal Chem; 2005 Mar 01; 77(5):1432-9. PubMed ID: 15732928 [Abstract] [Full Text] [Related]
7. Quantitation of therapeutic proteins following direct trypsin digestion of dried blood spot samples and detection by LC-MS-based bioanalytical methods in drug discovery. Sleczka BG, D'Arienzo CJ, Tymiak AA, Olah TV. Bioanalysis; 2012 Jan 01; 4(1):29-40. PubMed ID: 22191592 [Abstract] [Full Text] [Related]
8. Liquid chromatography/tandem mass spectrometry based targeted proteomics quantification of P-glycoprotein in various biological samples. Zhang Y, Li N, Brown PW, Ozer JS, Lai Y. Rapid Commun Mass Spectrom; 2011 Jun 30; 25(12):1715-24. PubMed ID: 21598331 [Abstract] [Full Text] [Related]
10. Importance of neonatal FcR in regulating the serum half-life of therapeutic proteins containing the Fc domain of human IgG1: a comparative study of the affinity of monoclonal antibodies and Fc-fusion proteins to human neonatal FcR. Suzuki T, Ishii-Watabe A, Tada M, Kobayashi T, Kanayasu-Toyoda T, Kawanishi T, Yamaguchi T. J Immunol; 2010 Feb 15; 184(4):1968-76. PubMed ID: 20083659 [Abstract] [Full Text] [Related]
14. General LC-MS/MS method approach to quantify therapeutic monoclonal antibodies using a common whole antibody internal standard with application to preclinical studies. Li H, Ortiz R, Tran L, Hall M, Spahr C, Walker K, Laudemann J, Miller S, Salimi-Moosavi H, Lee JW. Anal Chem; 2012 Feb 07; 84(3):1267-73. PubMed ID: 22243404 [Abstract] [Full Text] [Related]
15. Regulated LC-MS/MS bioanalysis technology for therapeutic antibodies and Fc-fusion proteins using structure-indicated approach. Iwamoto N, Shimada T. Drug Metab Pharmacokinet; 2019 Feb 07; 34(1):19-24. PubMed ID: 30392772 [Abstract] [Full Text] [Related]
16. Quantification of in vivo site-specific Asp isomerization and Asn deamidation of mAbs in animal serum using IP-LC-MS. Mehl JT, Sleczka BG, Ciccimaro EF, Kozhich AT, Gilbertson DG, Vuppugalla R, Huang CS, Stevens B, Mo J, Deyanova EG, Wang Y, Huang RY, Chen G, Olah TV. Bioanalysis; 2016 Aug 07; 8(15):1611-1622. PubMed ID: 27397670 [Abstract] [Full Text] [Related]