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194 related items for PubMed ID: 22625877
1. Impact of the CYP2C8 *3 polymorphism on the drug-drug interaction between gemfibrozil and pioglitazone. Aquilante CL, Kosmiski LA, Bourne DW, Bushman LR, Daily EB, Hammond KP, Hopley CW, Kadam RS, Kanack AT, Kompella UB, Le M, Predhomme JA, Rower JE, Sidhom MS. Br J Clin Pharmacol; 2013 Jan; 75(1):217-26. PubMed ID: 22625877 [Abstract] [Full Text] [Related]
2. Effects of gemfibrozil, itraconazole, and their combination on the pharmacokinetics of pioglitazone. Jaakkola T, Backman JT, Neuvonen M, Neuvonen PJ. Clin Pharmacol Ther; 2005 May; 77(5):404-14. PubMed ID: 15900286 [Abstract] [Full Text] [Related]
3. Effect of gemfibrozil on the pharmacokinetics of pioglitazone. Deng LJ, Wang F, Li HD. Eur J Clin Pharmacol; 2005 Dec; 61(11):831-6. PubMed ID: 16283275 [Abstract] [Full Text] [Related]
4. Influence of CYP2C8*2 on the pharmacokinetics of pioglitazone in healthy African-American volunteers. Aquilante CL, Wempe MF, Spencer SH, Kosmiski LA, Predhomme JA, Sidhom MS. Pharmacotherapy; 2013 Sep; 33(9):1000-7. PubMed ID: 23712614 [Abstract] [Full Text] [Related]
5. CYP2C8 but not CYP3A4 is important in the pharmacokinetics of montelukast. Karonen T, Neuvonen PJ, Backman JT. Br J Clin Pharmacol; 2012 Feb; 73(2):257-67. PubMed ID: 21838784 [Abstract] [Full Text] [Related]
6. Stereoselective interaction between the CYP2C8 inhibitor gemfibrozil and racemic ibuprofen. Tornio A, Niemi M, Neuvonen PJ, Backman JT. Eur J Clin Pharmacol; 2007 May; 63(5):463-9. PubMed ID: 17333159 [Abstract] [Full Text] [Related]
8. Trimethoprim and the CYP2C8*3 allele have opposite effects on the pharmacokinetics of pioglitazone. Tornio A, Niemi M, Neuvonen PJ, Backman JT. Drug Metab Dispos; 2008 Jan; 36(1):73-80. PubMed ID: 17913794 [Abstract] [Full Text] [Related]
9. Clopidogrel and Gemfibrozil Strongly Inhibit the CYP2C8-Dependent Formation of 3-Hydroxydesloratadine and Increase Desloratadine Exposure In Humans. Itkonen MK, Tornio A, Neuvonen M, Neuvonen PJ, Niemi M, Backman JT. Drug Metab Dispos; 2019 Apr; 47(4):377-385. PubMed ID: 30630815 [Abstract] [Full Text] [Related]
10. Underlying mechanism of drug-drug interaction between pioglitazone and gemfibrozil: Gemfibrozil acyl-glucuronide is a mechanism-based inhibitor of CYP2C8. Takagi M, Sakamoto M, Itoh T, Fujiwara R. Drug Metab Pharmacokinet; 2015 Aug; 30(4):288-94. PubMed ID: 26195223 [Abstract] [Full Text] [Related]
12. The CYP2C8 inhibitor gemfibrozil does not increase the plasma concentrations of zopiclone. Tornio A, Neuvonen PJ, Backman JT. Eur J Clin Pharmacol; 2006 Aug; 62(8):645-51. PubMed ID: 16832679 [Abstract] [Full Text] [Related]
14. Pioglitazone, an in vitro inhibitor of CYP2C8 and CYP3A4, does not increase the plasma concentrations of the CYP2C8 and CYP3A4 substrate repaglinide. Kajosaari LI, Jaakkola T, Neuvonen PJ, Backman JT. Eur J Clin Pharmacol; 2006 Mar; 62(3):217-23. PubMed ID: 16447051 [Abstract] [Full Text] [Related]
15. Gemfibrozil is a strong inactivator of CYP2C8 in very small multiple doses. Honkalammi J, Niemi M, Neuvonen PJ, Backman JT. Clin Pharmacol Ther; 2012 May; 91(5):846-55. PubMed ID: 22472994 [Abstract] [Full Text] [Related]
18. Effect of gemfibrozil and rifampicin on the pharmacokinetics of selexipag and its active metabolite in healthy subjects. Bruderer S, Petersen-Sylla M, Boehler M, Remeňová T, Halabi A, Dingemanse J. Br J Clin Pharmacol; 2017 Dec; 83(12):2778-2788. PubMed ID: 28715853 [Abstract] [Full Text] [Related]
19. Itraconazole, gemfibrozil and their combination markedly raise the plasma concentrations of loperamide. Niemi M, Tornio A, Pasanen MK, Fredrikson H, Neuvonen PJ, Backman JT. Eur J Clin Pharmacol; 2006 Jun; 62(6):463-72. PubMed ID: 16758263 [Abstract] [Full Text] [Related]
20. The CYP2C8 inhibitor gemfibrozil does not affect the pharmacokinetics of zafirlukast. Karonen T, Neuvonen PJ, Backman JT. Eur J Clin Pharmacol; 2011 Feb; 67(2):151-5. PubMed ID: 20931329 [Abstract] [Full Text] [Related] Page: [Next] [New Search]