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Journal Abstract Search

240 related items for PubMed ID: 22631565

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  • 2. Automated definition of the enzymology of drug oxidation by the major human drug metabolizing cytochrome P450s.
    McGinnity DF, Parker AJ, Soars M, Riley RJ.
    Drug Metab Dispos; 2000 Nov; 28(11):1327-34. PubMed ID: 11038161
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  • 3. Rapid characterization of the major drug-metabolizing human hepatic cytochrome P-450 enzymes expressed in Escherichia coli.
    McGinnity DF, Griffin SJ, Moody GC, Voice M, Hanlon S, Friedberg T, Riley RJ.
    Drug Metab Dispos; 1999 Sep; 27(9):1017-23. PubMed ID: 10460801
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  • 4. Designing better drugs: predicting cytochrome P450 metabolism.
    de Groot MJ.
    Drug Discov Today; 2006 Jul; 11(13-14):601-6. PubMed ID: 16793528
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  • 6. Utility of intersystem extrapolation factors in early reaction phenotyping and the quantitative extrapolation of human liver microsomal intrinsic clearance using recombinant cytochromes P450.
    Chen Y, Liu L, Nguyen K, Fretland AJ.
    Drug Metab Dispos; 2011 Mar; 39(3):373-82. PubMed ID: 21148079
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  • 9. Identification of the human liver cytochrome P450 isoenzymes responsible for the 5-methylhydroxylation of the novel anti-fibrotic drug AKF-PD.
    He X, Luo X, Liu Z, Hu G, Cheng Z.
    Xenobiotica; 2011 Oct; 41(10):844-50. PubMed ID: 21679010
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  • 10. Evaluation of recombinant cytochrome P450 enzymes as an in vitro system for metabolic clearance predictions.
    Stringer RA, Strain-Damerell C, Nicklin P, Houston JB.
    Drug Metab Dispos; 2009 May; 37(5):1025-34. PubMed ID: 19196847
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  • 12. RS-Predictor models augmented with SMARTCyp reactivities: robust metabolic regioselectivity predictions for nine CYP isozymes.
    Zaretzki J, Rydberg P, Bergeron C, Bennett KP, Olsen L, Breneman CM.
    J Chem Inf Model; 2012 Jun 25; 52(6):1637-59. PubMed ID: 22524152
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  • 13. SMARTCyp: A 2D Method for Prediction of Cytochrome P450-Mediated Drug Metabolism.
    Rydberg P, Gloriam DE, Zaretzki J, Breneman C, Olsen L.
    ACS Med Chem Lett; 2010 Jun 10; 1(3):96-100. PubMed ID: 24936230
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  • 14. In vitro metabolism of carbofuran by human, mouse, and rat cytochrome P450 and interactions with chlorpyrifos, testosterone, and estradiol.
    Usmani KA, Hodgson E, Rose RL.
    Chem Biol Interact; 2004 Dec 07; 150(3):221-32. PubMed ID: 15560889
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  • 18. Predicting drug metabolism by cytochrome P450 2C9: comparison with the 2D6 and 3A4 isoforms.
    Rydberg P, Olsen L.
    ChemMedChem; 2012 Jul 07; 7(7):1202-9. PubMed ID: 22593031
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  • 19. Prediction of cytochrome P450 isoform responsible for metabolizing a drug molecule.
    Mishra NK, Agarwal S, Raghava GP.
    BMC Pharmacol; 2010 Jul 16; 10():8. PubMed ID: 20637097
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