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Journal Abstract Search


380 related items for PubMed ID: 22641217

  • 1. AML1-ETO targets and suppresses cathepsin G, a serine protease, which is able to degrade AML1-ETO in t(8;21) acute myeloid leukemia.
    Jin W, Wu K, Li YZ, Yang WT, Zou B, Zhang F, Zhang J, Wang KK.
    Oncogene; 2013 Apr 11; 32(15):1978-87. PubMed ID: 22641217
    [Abstract] [Full Text] [Related]

  • 2. AML1-ETO triggers epigenetic activation of early growth response gene l, inducing apoptosis in t(8;21) acute myeloid leukemia.
    Fu L, Huang W, Jing Y, Jiang M, Zhao Y, Shi J, Huang S, Xue X, Zhang Q, Tang J, Dou L, Wang L, Nervi C, Li Y, Yu L.
    FEBS J; 2014 Feb 11; 281(4):1123-31. PubMed ID: 24314118
    [Abstract] [Full Text] [Related]

  • 3. Multi-sites cleavage of leukemogenic AML1-ETO fusion protein by caspase-3 and its contribution to increased apoptotic sensitivity.
    Lu Y, Peng ZG, Yuan TT, Yin QQ, Xia L, Chen GQ.
    Leukemia; 2008 Feb 11; 22(2):378-86. PubMed ID: 17989718
    [Abstract] [Full Text] [Related]

  • 4. Targeting AML1/ETO-histone deacetylase repressor complex: a novel mechanism for valproic acid-mediated gene expression and cellular differentiation in AML1/ETO-positive acute myeloid leukemia cells.
    Liu S, Klisovic RB, Vukosavljevic T, Yu J, Paschka P, Huynh L, Pang J, Neviani P, Liu Z, Blum W, Chan KK, Perrotti D, Marcucci G.
    J Pharmacol Exp Ther; 2007 Jun 11; 321(3):953-60. PubMed ID: 17389244
    [Abstract] [Full Text] [Related]

  • 5. The fusion protein AML1-ETO in acute myeloid leukemia with translocation t(8;21) induces c-jun protein expression via the proximal AP-1 site of the c-jun promoter in an indirect, JNK-dependent manner.
    Elsässer A, Franzen M, Kohlmann A, Weisser M, Schnittger S, Schoch C, Reddy VA, Burel S, Zhang DE, Ueffing M, Tenen DG, Hiddemann W, Behre G.
    Oncogene; 2003 Aug 28; 22(36):5646-57. PubMed ID: 12944913
    [Abstract] [Full Text] [Related]

  • 6. Epigenetic Silencing of Eyes Absent 4 Gene by Acute Myeloid Leukemia 1-Eight-twenty-one Oncoprotein Contributes to Leukemogenesis in t(8;21) Acute Myeloid Leukemia.
    Huang S, Jiang MM, Chen GF, Qian K, Gao HH, Guan W, Shi JL, Liu AQ, Liu J, Wang BH, Li YH, Yu L.
    Chin Med J (Engl); 2016 Jun 05; 129(11):1355-62. PubMed ID: 27231175
    [Abstract] [Full Text] [Related]

  • 7. The AML1 gene: a transcription factor involved in the pathogenesis of myeloid and lymphoid leukemias.
    Lo Coco F, Pisegna S, Diverio D.
    Haematologica; 1997 Jun 05; 82(3):364-70. PubMed ID: 9234595
    [Abstract] [Full Text] [Related]

  • 8. The Hematopoietic Transcription Factors RUNX1 and ERG Prevent AML1-ETO Oncogene Overexpression and Onset of the Apoptosis Program in t(8;21) AMLs.
    Mandoli A, Singh AA, Prange KHM, Tijchon E, Oerlemans M, Dirks R, Ter Huurne M, Wierenga ATJ, Janssen-Megens EM, Berentsen K, Sharifi N, Kim B, Matarese F, Nguyen LN, Hubner NC, Rao NA, van den Akker E, Altucci L, Vellenga E, Stunnenberg HG, Martens JHA.
    Cell Rep; 2016 Nov 15; 17(8):2087-2100. PubMed ID: 27851970
    [Abstract] [Full Text] [Related]

  • 9. Repression of vascular endothelial growth factor expression by the runt-related transcription factor 1 in acute myeloid leukemia.
    Ter Elst A, Ma B, Scherpen FJ, de Jonge HJ, Douwes J, Wierenga AT, Schuringa JJ, Kamps WA, de Bont ES.
    Cancer Res; 2011 Apr 01; 71(7):2761-71. PubMed ID: 21447743
    [Abstract] [Full Text] [Related]

  • 10. MEIS2 Is an Oncogenic Partner in AML1-ETO-Positive AML.
    Vegi NM, Klappacher J, Oswald F, Mulaw MA, Mandoli A, Thiel VN, Bamezai S, Feder K, Martens JHA, Rawat VPS, Mandal T, Quintanilla-Martinez L, Spiekermann K, Hiddemann W, Döhner K, Döhner H, Stunnenberg HG, Feuring-Buske M, Buske C.
    Cell Rep; 2016 Jul 12; 16(2):498-507. PubMed ID: 27346355
    [Abstract] [Full Text] [Related]

  • 11. Leukemogenic AML1-ETO fusion protein upregulates expression of connexin 43: the role in AML 1-ETO-induced growth arrest in leukemic cells.
    Li X, Xu YB, Wang Q, Lu Y, Zheng Y, Wang YC, Lübbert M, Zhao KW, Chen GQ.
    J Cell Physiol; 2006 Sep 12; 208(3):594-601. PubMed ID: 16741927
    [Abstract] [Full Text] [Related]

  • 12. Transcription of the AML1/ETO chimera is guided by the P2 promoter of the AML1 gene in the Kasumi-1 cell line.
    Markova EN, Kantidze OL, Razin SV.
    Gene; 2012 Dec 01; 510(2):142-6. PubMed ID: 22995345
    [Abstract] [Full Text] [Related]

  • 13. Epigenetic silencing of microRNA-193a contributes to leukemogenesis in t(8;21) acute myeloid leukemia by activating the PTEN/PI3K signal pathway.
    Li Y, Gao L, Luo X, Wang L, Gao X, Wang W, Sun J, Dou L, Li J, Xu C, Wang L, Zhou M, Jiang M, Zhou J, Caligiuri MA, Nervi C, Bloomfield CD, Marcucci G, Yu L.
    Blood; 2013 Jan 17; 121(3):499-509. PubMed ID: 23223432
    [Abstract] [Full Text] [Related]

  • 14. Disruption of the NHR4 domain structure in AML1-ETO abrogates SON binding and promotes leukemogenesis.
    Ahn EY, Yan M, Malakhova OA, Lo MC, Boyapati A, Ommen HB, Hines R, Hokland P, Zhang DE.
    Proc Natl Acad Sci U S A; 2008 Nov 04; 105(44):17103-8. PubMed ID: 18952841
    [Abstract] [Full Text] [Related]

  • 15. ZFP36L2, a novel AML1 target gene, induces AML cells apoptosis and inhibits cell proliferation.
    Liu J, Lu W, Liu S, Wang Y, Li S, Xu Y, Xing H, Tang K, Tian Z, Rao Q, Wang M, Wang J.
    Leuk Res; 2018 May 04; 68():15-21. PubMed ID: 29518627
    [Abstract] [Full Text] [Related]

  • 16. Inducible expression of AML1-ETO fusion protein endows leukemic cells with susceptibility to extrinsic and intrinsic apoptosis.
    Lu Y, Xu YB, Yuan TT, Song MG, Lübbert M, Fliegauf M, Chen GQ.
    Leukemia; 2006 Jun 04; 20(6):987-93. PubMed ID: 16598301
    [Abstract] [Full Text] [Related]

  • 17. PIG7, transactivated by AML1, promotes apoptosis and differentiation of leukemia cells with AML1-ETO fusion gene.
    Liu J, Xing H, Chen Y, Wang L, Wang D, Rao Q, Tang K, Tian Z, He K, Wang M, Wang J.
    Leukemia; 2012 Jan 04; 26(1):117-26. PubMed ID: 21836606
    [Abstract] [Full Text] [Related]

  • 18. AML1-ETO downregulates the granulocytic differentiation factor C/EBPalpha in t(8;21) myeloid leukemia.
    Pabst T, Mueller BU, Harakawa N, Schoch C, Haferlach T, Behre G, Hiddemann W, Zhang DE, Tenen DG.
    Nat Med; 2001 Apr 04; 7(4):444-51. PubMed ID: 11283671
    [Abstract] [Full Text] [Related]

  • 19. Genome-wide co-occupancy of AML1-ETO and N-CoR defines the t(8;21) AML signature in leukemic cells.
    Trombly DJ, Whitfield TW, Padmanabhan S, Gordon JA, Lian JB, van Wijnen AJ, Zaidi SK, Stein JL, Stein GS.
    BMC Genomics; 2015 Apr 17; 16(1):309. PubMed ID: 25928846
    [Abstract] [Full Text] [Related]

  • 20. A previously unidentified alternatively spliced isoform of t(8;21) transcript promotes leukemogenesis.
    Yan M, Kanbe E, Peterson LF, Boyapati A, Miao Y, Wang Y, Chen IM, Chen Z, Rowley JD, Willman CL, Zhang DE.
    Nat Med; 2006 Aug 17; 12(8):945-9. PubMed ID: 16892037
    [Abstract] [Full Text] [Related]


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