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PUBMED FOR HANDHELDS

Journal Abstract Search


264 related items for PubMed ID: 22676247

  • 1. Synthesis and biological evaluation of 1-benzylidene-3,4-dihydronaphthalen-2-one as a new class of microtubule-targeting agents.
    Liu J, Zheng CH, Ren XH, Zhou F, Li W, Zhu J, Lv JG, Zhou YJ.
    J Med Chem; 2012 Jun 28; 55(12):5720-33. PubMed ID: 22676247
    [Abstract] [Full Text] [Related]

  • 2. Conformationnally restricted naphthalene derivatives type isocombretastatin A-4 and isoerianin analogues: synthesis, cytotoxicity and antitubulin activity.
    Rasolofonjatovo E, Provot O, Hamze A, Rodrigo J, Bignon J, Wdzieczak-Bakala J, Desravines D, Dubois J, Brion JD, Alami M.
    Eur J Med Chem; 2012 Jun 28; 52():22-32. PubMed ID: 22449653
    [Abstract] [Full Text] [Related]

  • 3. 9-Benzylidene-naphtho[2,3-b]thiophen-4-ones as novel antimicrotubule agents-synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Zuse A, Schmidt P, Baasner S, Böhm KJ, Müller K, Gerlach M, Günther EG, Unger E, Prinz H.
    J Med Chem; 2006 Dec 28; 49(26):7816-25. PubMed ID: 17181164
    [Abstract] [Full Text] [Related]

  • 4. Design, synthesis, biological evaluation and molecular modeling of 1,3,4-oxadiazoline analogs of combretastatin-A4 as novel antitubulin agents.
    Hu Y, Lu X, Chen K, Yan R, Li QS, Zhu HL.
    Bioorg Med Chem; 2012 Jan 15; 20(2):903-9. PubMed ID: 22192936
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and biological evaluation of 3,4-diaryl-5-aminoisoxazole derivatives.
    Liu T, Dong X, Xue N, Wu R, He Q, Yang B, Hu Y.
    Bioorg Med Chem; 2009 Sep 01; 17(17):6279-85. PubMed ID: 19665898
    [Abstract] [Full Text] [Related]

  • 6. Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxybenzoyl)-5-aryl thiophenes as a new class of potent antitubulin agents.
    Romagnoli R, Baraldi PG, Pavani MG, Tabrizi MA, Preti D, Fruttarolo F, Piccagli L, Jung MK, Hamel E, Borgatti M, Gambari R.
    J Med Chem; 2006 Jun 29; 49(13):3906-15. PubMed ID: 16789746
    [Abstract] [Full Text] [Related]

  • 7. Synthesis and biological evaluation of a series of podophyllotoxins derivatives as a class of potent antitubulin agents.
    Liu Y, Wei D, Zhao Y, Cheng W, Lu Y, Ma Y, Li X, Han C, Wei Y, Cao H, Zhao C.
    Bioorg Med Chem; 2012 Nov 01; 20(21):6285-95. PubMed ID: 23022053
    [Abstract] [Full Text] [Related]

  • 8. Sulfonate derivatives of naphtho[2,3-b]thiophen-4(9H)-one and 9(10H)-anthracenone as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Zuse A, Schmidt P, Baasner S, Böhm KJ, Müller K, Gerlach M, Günther EG, Unger E, Prinz H.
    J Med Chem; 2007 Nov 29; 50(24):6059-66. PubMed ID: 17973361
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and anticancer activity of 2-benzylidene indanones through inhibiting tubulin polymerization.
    Prakasham AP, Saxena AK, Luqman S, Chanda D, Kaur T, Gupta A, Yadav DK, Chanotiya CS, Shanker K, Khan F, Negi AS.
    Bioorg Med Chem; 2012 May 01; 20(9):3049-57. PubMed ID: 22472045
    [Abstract] [Full Text] [Related]

  • 10. Design, synthesis and biological evaluation of millepachine derivatives as a new class of tubulin polymerization inhibitors.
    Wang G, Peng F, Cao D, Yang Z, Han X, Liu J, Wu W, He L, Ma L, Chen J, Sang Y, Xiang M, Peng A, Wei Y, Chen L.
    Bioorg Med Chem; 2013 Nov 01; 21(21):6844-54. PubMed ID: 23993668
    [Abstract] [Full Text] [Related]

  • 11. Synthesis of macrocyclic bisbibenzyl derivatives and their anticancer effects as anti-tubulin agents.
    Jiang J, Sun B, Wang YY, Cui M, Zhang L, Cui CZ, Wang YF, Liu XG, Lou HX.
    Bioorg Med Chem; 2012 Apr 01; 20(7):2382-91. PubMed ID: 22365913
    [Abstract] [Full Text] [Related]

  • 12. Synthesis and biological evaluation of novel pyranochalcone derivatives as a new class of microtubule stabilizing agents.
    Cao D, Han X, Wang G, Yang Z, Peng F, Ma L, Zhang R, Ye H, Tang M, Wu W, Lei K, Wen J, Chen J, Qiu J, Liang X, Ran Y, Sang Y, Xiang M, Peng A, Chen L.
    Eur J Med Chem; 2013 Apr 01; 62():579-89. PubMed ID: 23425970
    [Abstract] [Full Text] [Related]

  • 13. Design, synthesis, and biological evaluation of thiophene analogues of chalcones.
    Romagnoli R, Baraldi PG, Carrion MD, Cara CL, Cruz-Lopez O, Preti D, Tolomeo M, Grimaudo S, Di Cristina A, Zonta N, Balzarini J, Brancale A, Sarkar T, Hamel E.
    Bioorg Med Chem; 2008 May 15; 16(10):5367-76. PubMed ID: 18440234
    [Abstract] [Full Text] [Related]

  • 14. Synthesis and biological evaluation of novel pyrano[3,2-c]carbazole derivatives as anti-tumor agents inducing apoptosis via tubulin polymerization inhibition.
    Padmaja P, Koteswara Rao G, Indrasena A, Subba Reddy BV, Patel N, Shaik AB, Reddy N, Dubey PK, Bhadra MP.
    Org Biomol Chem; 2015 Feb 07; 13(5):1404-14. PubMed ID: 25467166
    [Abstract] [Full Text] [Related]

  • 15. Synthesis and anticancer activity of analogues of phenstatin, with a phenothiazine A-ring, as a new class of microtubule-targeting agents.
    Abuhaie CM, Bîcu E, Rigo B, Gautret P, Belei D, Farce A, Dubois J, Ghinet A.
    Bioorg Med Chem Lett; 2013 Jan 01; 23(1):147-52. PubMed ID: 23200248
    [Abstract] [Full Text] [Related]

  • 16. Synthesis, biological evaluation, and molecular docking studies of novel 1-benzene acyl-2-(1-methylindol-3-yl)-benzimidazole derivatives as potential tubulin polymerization inhibitors.
    Wang YT, Qin YJ, Yang N, Zhang YL, Liu CH, Zhu HL.
    Eur J Med Chem; 2015 Jun 24; 99():125-37. PubMed ID: 26070164
    [Abstract] [Full Text] [Related]

  • 17. Design, synthesis and biological evaluation of a series of pyrano chalcone derivatives containing indole moiety as novel anti-tubulin agents.
    Wang G, Li C, He L, Lei K, Wang F, Pu Y, Yang Z, Cao D, Ma L, Chen J, Sang Y, Liang X, Xiang M, Peng A, Wei Y, Chen L.
    Bioorg Med Chem; 2014 Apr 01; 22(7):2060-79. PubMed ID: 24629450
    [Abstract] [Full Text] [Related]

  • 18. Design, synthesis, and biological evaluation of novel N-γ-carboline arylsulfonamides as anticancer agents.
    Chen J, Liu T, Wu R, Lou J, Cao J, Dong X, Yang B, He Q, Hu Y.
    Bioorg Med Chem; 2010 Dec 15; 18(24):8478-84. PubMed ID: 21067933
    [Abstract] [Full Text] [Related]

  • 19. Synthesis, molecular modeling and biological evaluation of guanidine derivatives as novel antitubulin agents.
    Qian Y, Zhang HJ, Lv PC, Zhu HL.
    Bioorg Med Chem; 2010 Dec 01; 18(23):8218-25. PubMed ID: 21036623
    [Abstract] [Full Text] [Related]

  • 20. Design, synthesis, and biological evaluation of novel γ-carboline ketones as anticancer agents.
    Chen J, Liu T, Wu R, Lou J, Dong X, He Q, Yang B, Hu Y.
    Eur J Med Chem; 2011 Apr 01; 46(4):1343-7. PubMed ID: 21342735
    [Abstract] [Full Text] [Related]


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