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Journal Abstract Search

264 related items for PubMed ID: 22676247

  • 21. Synthesis and structure-activity relationships of 2-amino-1-aroylnaphthalene and 2-hydroxy-1-aroylnaphthalenes as potent antitubulin agents.
    Reddy GR, Kuo CC, Tan UK, Coumar MS, Chang CY, Chiang YK, Lai MJ, Yeh JY, Wu SY, Chang JY, Liou JP, Hsieh HP.
    J Med Chem; 2008 Dec 25; 51(24):8163-7. PubMed ID: 19053773
    [Abstract] [Full Text] [Related]

  • 22. N-benzoylated phenoxazines and phenothiazines: synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Prinz H, Chamasmani B, Vogel K, Böhm KJ, Aicher B, Gerlach M, Günther EG, Amon P, Ivanov I, Müller K.
    J Med Chem; 2011 Jun 23; 54(12):4247-63. PubMed ID: 21563750
    [Abstract] [Full Text] [Related]

  • 23. 5-Amino-2-aroylquinolines as highly potent tubulin polymerization inhibitors.
    Nien CY, Chen YC, Kuo CC, Hsieh HP, Chang CY, Wu JS, Wu SY, Liou JP, Chang JY.
    J Med Chem; 2010 Mar 11; 53(5):2309-13. PubMed ID: 20148562
    [Abstract] [Full Text] [Related]

  • 24. Synthesis, biological evaluation and molecular docking studies of resveratrol derivatives possessing curcumin moiety as potent antitubulin agents.
    Ruan BF, Lu X, Li TT, Tang JF, Wei Y, Wang XL, Zheng SL, Yao RS, Zhu HL.
    Bioorg Med Chem; 2012 Jan 15; 20(2):1113-21. PubMed ID: 22189271
    [Abstract] [Full Text] [Related]

  • 25. Synthesis and biological evaluation of 1-phenyl-1,2,3,4-dihydroisoquinoline compounds as tubulin polymerization inhibitors.
    Zheng CH, Chen J, Liu J, Zhou XT, Liu N, Shi D, Huang JJ, Lv JG, Zhu J, Zhou YJ.
    Arch Pharm (Weinheim); 2012 Jun 15; 345(6):454-62. PubMed ID: 22415658
    [Abstract] [Full Text] [Related]

  • 26. Novel benzylidene-9(10H)-anthracenones as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Prinz H, Ishii Y, Hirano T, Stoiber T, Camacho Gomez JA, Schmidt P, Düssmann H, Burger AM, Prehn JH, Günther EG, Unger E, Umezawa K.
    J Med Chem; 2003 Jul 17; 46(15):3382-94. PubMed ID: 12852768
    [Abstract] [Full Text] [Related]

  • 27. Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity.
    Chiang YK, Kuo CC, Wu YS, Chen CT, Coumar MS, Wu JS, Hsieh HP, Chang CY, Jseng HY, Wu MH, Leou JS, Song JS, Chang JY, Lyu PC, Chao YS, Wu SY.
    J Med Chem; 2009 Jul 23; 52(14):4221-33. PubMed ID: 19507860
    [Abstract] [Full Text] [Related]

  • 28. Design, Synthesis, and Biological Evaluation of Chalcone-Containing Shikonin Derivatives as Inhibitors of Tubulin Polymerization.
    Qiu HY, Wang F, Wang X, Sun WX, Qi JL, Pang YJ, Yang RW, Lu GH, Wang XM, Yang YH.
    ChemMedChem; 2017 Mar 07; 12(5):399-406. PubMed ID: 28211616
    [Abstract] [Full Text] [Related]

  • 29. 2-amino-3,4,5-trimethoxybenzophenones as potent tubulin polymerization inhibitors.
    Chuang HY, Chang JY, Lai MJ, Kuo CC, Lee HY, Hsieh HP, Chen YJ, Chen LT, Pan WY, Liou JP.
    ChemMedChem; 2011 Mar 07; 6(3):450-6. PubMed ID: 21360819
    [Abstract] [Full Text] [Related]

  • 30. Discovery of novel 2-N-aryl-substituted benzenesulfonamidoacetamides: orally bioavailable tubulin polymerization inhibitors with marked antitumor activities.
    Liu Z, Zhou Z, Tian W, Fan X, Xue D, Yu L, Yu Q, Long YQ.
    ChemMedChem; 2012 Apr 07; 7(4):680-93. PubMed ID: 22311585
    [Abstract] [Full Text] [Related]

  • 31. Synthesis and evaluation of benzimidazole carbamates bearing indole moieties for antiproliferative and antitubulin activities.
    Guan Q, Han C, Zuo D, Zhai M, Li Z, Zhang Q, Zhai Y, Jiang X, Bao K, Wu Y, Zhang W.
    Eur J Med Chem; 2014 Nov 24; 87():306-15. PubMed ID: 25262051
    [Abstract] [Full Text] [Related]

  • 32. Synthesis of a terphenyl substituted 4-aza-2,3-didehydropodophyllotoxin analogues as inhibitors of tubulin polymerization and apoptosis inducers.
    Kamal A, Tamboli JR, Nayak VL, Adil SF, Vishnuvardhan MV, Ramakrishna S.
    Bioorg Med Chem; 2014 May 01; 22(9):2714-23. PubMed ID: 24721832
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  • 33. Regioselective Suzuki coupling of dihaloheteroaromatic compounds as a rapid strategy to synthesize potent rigid combretastatin analogues.
    Theeramunkong S, Caldarelli A, Massarotti A, Aprile S, Caprioglio D, Zaninetti R, Teruggi A, Pirali T, Grosa G, Tron GC, Genazzani AA.
    J Med Chem; 2011 Jul 28; 54(14):4977-86. PubMed ID: 21696175
    [Abstract] [Full Text] [Related]

  • 34. Quinazolinone-Based Anticancer Agents: Synthesis, Antiproliferative SAR, Antitubulin Activity, and Tubulin Co-crystal Structure.
    Dohle W, Jourdan FL, Menchon G, Prota AE, Foster PA, Mannion P, Hamel E, Thomas MP, Kasprzyk PG, Ferrandis E, Steinmetz MO, Leese MP, Potter BVL.
    J Med Chem; 2018 Feb 08; 61(3):1031-1044. PubMed ID: 29227648
    [Abstract] [Full Text] [Related]

  • 35. Design, synthesis and biological evaluation of novel pyrazoline-containing derivatives as potential tubulin assembling inhibitors.
    Qin YJ, Li YJ, Jiang AQ, Yang MR, Zhu QZ, Dong H, Zhu HL.
    Eur J Med Chem; 2015 Apr 13; 94():447-57. PubMed ID: 25828827
    [Abstract] [Full Text] [Related]

  • 36. Naphthylphenstatins as tubulin ligands: synthesis and biological evaluation.
    Alvarez C, Alvarez R, Corchete P, Pérez-Melero C, Peláez R, Medarde M.
    Bioorg Med Chem; 2008 Oct 01; 16(19):8999-9008. PubMed ID: 18790642
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  • 37. Design, synthesis and anticancer properties of IsoCombretaQuinolines as potent tubulin assembly inhibitors.
    Khelifi I, Naret T, Renko D, Hamze A, Bernadat G, Bignon J, Lenoir C, Dubois J, Brion JD, Provot O, Alami M.
    Eur J Med Chem; 2017 Feb 15; 127():1025-1034. PubMed ID: 28166995
    [Abstract] [Full Text] [Related]

  • 38. Synthesis, antiproliferative activity and inhibition of tubulin polymerization by 1,5- and 1,8-disubstituted 10H-anthracen-9-ones bearing a 10-benzylidene or 10-(2-oxo-2-phenylethylidene) moiety.
    Nickel HC, Schmidt P, Böhm KJ, Baasner S, Müller K, Gerlach M, Unger E, Günther EG, Prinz H.
    Eur J Med Chem; 2010 Aug 15; 45(8):3420-38. PubMed ID: 20537765
    [Abstract] [Full Text] [Related]

  • 39. 4,5-Diaryl-3H-1,2-dithiole-3-thiones and related compounds as combretastatin A-4/oltipraz hybrids: Synthesis, molecular modelling and evaluation as antiproliferative agents and inhibitors of tubulin.
    Wang Z, Qi H, Shen Q, Lu G, Li M, Bao K, Wu Y, Zhang W.
    Eur J Med Chem; 2016 Oct 21; 122():520-529. PubMed ID: 27428395
    [Abstract] [Full Text] [Related]

  • 40. Synthesis and biological evaluation of 2,4,5-substituted pyrimidines as a new class of tubulin polymerization inhibitors.
    Xie F, Zhao H, Li D, Chen H, Quan H, Shi X, Lou L, Hu Y.
    J Med Chem; 2011 May 12; 54(9):3200-5. PubMed ID: 21480626
    [Abstract] [Full Text] [Related]

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