These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

191 related items for PubMed ID: 22685215

  • 1. Mechanism-based inactivation of cytochrome P450 2B6 by methadone through destruction of prosthetic heme.
    Amunugama HT, Zhang H, Hollenberg PF.
    Drug Metab Dispos; 2012 Sep; 40(9):1765-70. PubMed ID: 22685215
    [Abstract] [Full Text] [Related]

  • 2. Metabolic activation of mifepristone [RU486; 17beta-hydroxy-11beta-(4-dimethylaminophenyl)-17alpha-(1-propynyl)-estra-4,9-dien-3-one] by mammalian cytochromes P450 and the mechanism-based inactivation of human CYP2B6.
    Lin HL, Zhang H, Hollenberg PF.
    J Pharmacol Exp Ther; 2009 Apr; 329(1):26-37. PubMed ID: 19168709
    [Abstract] [Full Text] [Related]

  • 3. The grapefruit juice effect is not limited to cytochrome P450 (P450) 3A4: evidence for bergamottin-dependent inactivation, heme destruction, and covalent binding to protein in P450s 2B6 and 3A5.
    Lin HL, Kent UM, Hollenberg PF.
    J Pharmacol Exp Ther; 2005 Apr; 313(1):154-64. PubMed ID: 15608076
    [Abstract] [Full Text] [Related]

  • 4. Mechanism-based inactivation of human cytochrome P450 2B6 by clopidogrel: involvement of both covalent modification of cysteinyl residue 475 and loss of heme.
    Zhang H, Amunugama H, Ney S, Cooper N, Hollenberg PF.
    Mol Pharmacol; 2011 Nov; 80(5):839-47. PubMed ID: 21862689
    [Abstract] [Full Text] [Related]

  • 5.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 6. The mechanism-based inactivation of human cytochrome P450 2B6 by phencyclidine.
    Jushchyshyn MI, Kent UM, Hollenberg PF.
    Drug Metab Dispos; 2003 Jan; 31(1):46-52. PubMed ID: 12485952
    [Abstract] [Full Text] [Related]

  • 7. Metabolism of N,N',N"-triethylenethiophosphoramide by CYP2B1 and CYP2B6 results in the inactivation of both isoforms by two distinct mechanisms.
    Harleton E, Webster M, Bumpus NN, Kent UM, Rae JM, Hollenberg PF.
    J Pharmacol Exp Ther; 2004 Sep; 310(3):1011-9. PubMed ID: 15121764
    [Abstract] [Full Text] [Related]

  • 8. Stereoselective metabolism of methadone N-demethylation by cytochrome P4502B6 and 2C19.
    Gerber JG, Rhodes RJ, Gal J.
    Chirality; 2004 Jan; 16(1):36-44. PubMed ID: 14628297
    [Abstract] [Full Text] [Related]

  • 9.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 10.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 11.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 12.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 13. Mechanistic analysis of the inactivation of cytochrome P450 2B6 by phencyclidine: effects on substrate binding, electron transfer, and uncoupling.
    Shebley M, Kent UM, Ballou DP, Hollenberg PF.
    Drug Metab Dispos; 2009 Apr; 37(4):745-52. PubMed ID: 19144770
    [Abstract] [Full Text] [Related]

  • 14.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 15.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 16.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 17. Role of cytochrome P4502B6 in methadone metabolism and clearance.
    Kharasch ED, Stubbert K.
    J Clin Pharmacol; 2013 Mar; 53(3):305-13. PubMed ID: 23361846
    [Abstract] [Full Text] [Related]

  • 18.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 19. Mechanism-based inactivation of cytochromes P450 2E1 and 2E1 T303A by tert-butyl acetylenes: characterization of reactive intermediate adducts to the heme and apoprotein.
    Blobaum AL, Kent UM, Alworth WL, Hollenberg PF.
    Chem Res Toxicol; 2002 Dec; 15(12):1561-71. PubMed ID: 12482238
    [Abstract] [Full Text] [Related]

  • 20.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 10.