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562 related items for PubMed ID: 22694478

  • 1. The apoptotic effect and associated signalling of HSP90 inhibitor 17-DMAG in hepatocellular carcinoma cells.
    Leng AM, Liu T, Yang J, Cui JF, Li XH, Zhu YN, Xiong T, Zhang G, Chen Y.
    Cell Biol Int; 2012 Oct 01; 36(10):893-9. PubMed ID: 22694478
    [Abstract] [Full Text] [Related]

  • 2. Efficacy of Hsp90 inhibition for induction of apoptosis and inhibition of growth in cervical carcinoma cells in vitro and in vivo.
    Schwock J, Pham NA, Cao MP, Hedley DW.
    Cancer Chemother Pharmacol; 2008 Apr 01; 61(4):669-81. PubMed ID: 17579866
    [Abstract] [Full Text] [Related]

  • 3. 17-AAG and 17-DMAG-induced inhibition of cell proliferation through B-Raf downregulation in WT B-Raf-expressing uveal melanoma cell lines.
    Babchia N, Calipel A, Mouriaux F, Faussat AM, Mascarelli F.
    Invest Ophthalmol Vis Sci; 2008 Jun 01; 49(6):2348-56. PubMed ID: 18281615
    [Abstract] [Full Text] [Related]

  • 4. Hypoxia attenuates Hsp90 inhibitor 17-DMAG-induced cyclin B1 accumulation in hepatocellular carcinoma cells.
    Zhang J, Li H, Huang Z, He Y, Zhou X, Huang T, Dai P, Duan D, Ma X, Yin Q, Wang X, Liu H, Chen S, Zou F, Chen X.
    Cell Stress Chaperones; 2016 Mar 01; 21(2):339-48. PubMed ID: 26786409
    [Abstract] [Full Text] [Related]

  • 5. Menatetrenone, a vitamin K2 analogue, inhibits hepatocellular carcinoma cell growth by suppressing cyclin D1 expression through inhibition of nuclear factor kappaB activation.
    Ozaki I, Zhang H, Mizuta T, Ide Y, Eguchi Y, Yasutake T, Sakamaki T, Pestell RG, Yamamoto K.
    Clin Cancer Res; 2007 Apr 01; 13(7):2236-45. PubMed ID: 17404108
    [Abstract] [Full Text] [Related]

  • 6. Schedule-dependent synergy between the heat shock protein 90 inhibitor 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin and doxorubicin restores apoptosis to p53-mutant lymphoma cell lines.
    Robles AI, Wright MH, Gandhi B, Feis SS, Hanigan CL, Wiestner A, Varticovski L.
    Clin Cancer Res; 2006 Nov 01; 12(21):6547-56. PubMed ID: 17085670
    [Abstract] [Full Text] [Related]

  • 7. The anti-proliferative effect of heat shock protein 90 inhibitor, 17-DMAG, on non-small-cell lung cancers being resistant to EGFR tyrosine kinase inhibitor.
    Kobayashi N, Toyooka S, Soh J, Yamamoto H, Dote H, Kawasaki K, Otani H, Kubo T, Jida M, Ueno T, Ando M, Ogino A, Kiura K, Miyoshi S.
    Lung Cancer; 2012 Feb 01; 75(2):161-6. PubMed ID: 21767894
    [Abstract] [Full Text] [Related]

  • 8. Anti-proliferative activity of heat shock protein (Hsp) 90 inhibitors via beta-catenin/TCF7L2 pathway in adult T cell leukemia cells.
    Kurashina R, Ohyashiki JH, Kobayashi C, Hamamura R, Zhang Y, Hirano T, Ohyashiki K.
    Cancer Lett; 2009 Oct 18; 284(1):62-70. PubMed ID: 19464103
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of heat shock protein 90 function by 17-allylamino-17-demethoxy-geldanamycin in Hodgkin's lymphoma cells down-regulates Akt kinase, dephosphorylates extracellular signal-regulated kinase, and induces cell cycle arrest and cell death.
    Georgakis GV, Li Y, Rassidakis GZ, Martinez-Valdez H, Medeiros LJ, Younes A.
    Clin Cancer Res; 2006 Jan 15; 12(2):584-90. PubMed ID: 16428504
    [Abstract] [Full Text] [Related]

  • 10. 17-DMAG induces heat shock protein 90 functional impairment in human bladder cancer cells: knocking down the hallmark traits of malignancy.
    Karkoulis PK, Stravopodis DJ, Voutsinas GE.
    Tumour Biol; 2016 May 15; 37(5):6861-73. PubMed ID: 26662567
    [Abstract] [Full Text] [Related]

  • 11. Geldanamycin inhibits tyrosine phosphorylation-dependent NF-kappaB activation.
    Crèvecoeur J, Merville MP, Piette J, Gloire G.
    Biochem Pharmacol; 2008 Jun 01; 75(11):2183-91. PubMed ID: 18455150
    [Abstract] [Full Text] [Related]

  • 12. [Effect of HSP90 function inhibited on the telomerase and P53 mutant in breast cancer cells].
    Li X, Deng HY.
    Sichuan Da Xue Xue Bao Yi Xue Ban; 2008 Mar 01; 39(2):181-3. PubMed ID: 18630678
    [Abstract] [Full Text] [Related]

  • 13. Heat shock protein 90 inhibitors attenuate inflammatory responses in atherosclerosis.
    Madrigal-Matute J, López-Franco O, Blanco-Colio LM, Muñoz-García B, Ramos-Mozo P, Ortega L, Egido J, Martín-Ventura JL.
    Cardiovasc Res; 2010 May 01; 86(2):330-7. PubMed ID: 20154064
    [Abstract] [Full Text] [Related]

  • 14. Inhibition of heat shock protein (Hsp) 90 potentiates the antiproliferative and pro-apoptotic effects of 2-(4'fluoro-phenylamino)-4H-1,3-thiazine[6,5-b]indole in A2780cis cells.
    Solárová Z, Kello M, Varinská L, Budovská M, Solár P.
    Biomed Pharmacother; 2017 Jan 01; 85():463-471. PubMed ID: 27887849
    [Abstract] [Full Text] [Related]

  • 15. Hyperthermia enhances 17-DMAG efficacy in hepatocellular carcinoma cells with aggravated DNA damage and impaired G2/M transition.
    Huang Z, Zhou X, He Y, Ke X, Wen Y, Zou F, Chen X.
    Sci Rep; 2016 Dec 02; 6():38072. PubMed ID: 27909289
    [Abstract] [Full Text] [Related]

  • 16. [Effects of 17-DMAG on non-small cell lung cancer cell lines A549 and H1975
 being resistant to EGFR-TKI].
    Zhao L, Cao F.
    Zhongguo Fei Ai Za Zhi; 2014 Nov 02; 17(11):778-82. PubMed ID: 25404267
    [Abstract] [Full Text] [Related]

  • 17. Dovitinib sensitizes hepatocellular carcinoma cells to TRAIL and tigatuzumab, a novel anti-DR5 antibody, through SHP-1-dependent inhibition of STAT3.
    Chen KF, Chen HL, Liu CY, Tai WT, Ichikawa K, Chen PJ, Cheng AL.
    Biochem Pharmacol; 2012 Mar 15; 83(6):769-77. PubMed ID: 22230479
    [Abstract] [Full Text] [Related]

  • 18. [Effect of heat shock protein 90 inhibitor 17-dimethylamino-ethylaminogeldanamycin on TNfalpha-mediated apoptosis and TNF-induced NF-kappaB activation].
    Zhong YJ, Wang X, Zheng XL, Yan YY, Liu XM, Liao LC.
    Sichuan Da Xue Xue Bao Yi Xue Ban; 2011 May 15; 42(3):303-7. PubMed ID: 21826987
    [Abstract] [Full Text] [Related]

  • 19. Swainsonine inhibits growth and potentiates the cytotoxic effect of paclitaxel in hepatocellular carcinoma in vitro and in vivo.
    You N, Liu W, Wang T, Ji R, Wang X, Gong Z, Dou K, Tao K.
    Oncol Rep; 2012 Dec 15; 28(6):2091-100. PubMed ID: 22993037
    [Abstract] [Full Text] [Related]

  • 20. 17-Allylamino-17-demethoxygeldanamycin and ritonavir inhibit renal cancer growth by inhibiting the expression of heat shock factor-1.
    Sato A, Asano T, Ito K, Asano T.
    Int J Oncol; 2012 Jul 15; 41(1):46-52. PubMed ID: 22470109
    [Abstract] [Full Text] [Related]

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