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Journal Abstract Search

109 related items for PubMed ID: 2271673

  • 1. Ligand exclusion on acetylcholinesterase.
    Berman HA, Leonard K.
    Biochemistry; 1990 Nov 27; 29(47):10640-9. PubMed ID: 2271673
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  • 2. Substrate binding to the peripheral site of acetylcholinesterase initiates enzymatic catalysis. Substrate inhibition arises as a secondary effect.
    Szegletes T, Mallender WD, Thomas PJ, Rosenberry TL.
    Biochemistry; 1999 Jan 05; 38(1):122-33. PubMed ID: 9890890
    [Abstract] [Full Text] [Related]

  • 3. Electrostatic influence on the kinetics of ligand binding to acetylcholinesterase. Distinctions between active center ligands and fasciculin.
    Radić Z, Kirchhoff PD, Quinn DM, McCammon JA, Taylor P.
    J Biol Chem; 1997 Sep 12; 272(37):23265-77. PubMed ID: 9287336
    [Abstract] [Full Text] [Related]

  • 4. Aspartate 74 as a primary determinant in acetylcholinesterase governing specificity to cationic organophosphonates.
    Hosea NA, Radić Z, Tsigelny I, Berman HA, Quinn DM, Taylor P.
    Biochemistry; 1996 Aug 20; 35(33):10995-1004. PubMed ID: 8718893
    [Abstract] [Full Text] [Related]

  • 5. Acetylthiocholine binds to asp74 at the peripheral site of human acetylcholinesterase as the first step in the catalytic pathway.
    Mallender WD, Szegletes T, Rosenberry TL.
    Biochemistry; 2000 Jul 04; 39(26):7753-63. PubMed ID: 10869180
    [Abstract] [Full Text] [Related]

  • 6. Chiral reactions of acetylcholinesterase probed with enantiomeric methylphosphonothioates. Noncovalent determinants of enzyme chirality.
    Berman HA, Leonard K.
    J Biol Chem; 1989 Mar 05; 264(7):3942-50. PubMed ID: 2917983
    [Abstract] [Full Text] [Related]

  • 7. Role of the peripheral anionic site on acetylcholinesterase: inhibition by substrates and coumarin derivatives.
    Radić Z, Reiner E, Taylor P.
    Mol Pharmacol; 1991 Jan 05; 39(1):98-104. PubMed ID: 1987454
    [Abstract] [Full Text] [Related]

  • 8. Enantiomeric inhibitors of cholesterol esterase and acetylcholinesterase.
    Lin G, Tsai YC, Liu HC, Liao WC, Chang CH.
    Biochim Biophys Acta; 1998 Oct 14; 1388(1):161-74. PubMed ID: 9774723
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  • 10. Nonequilibrium analysis alters the mechanistic interpretation of inhibition of acetylcholinesterase by peripheral site ligands.
    Szegletes T, Mallender WD, Rosenberry TL.
    Biochemistry; 1998 Mar 24; 37(12):4206-16. PubMed ID: 9521743
    [Abstract] [Full Text] [Related]

  • 11. The influence of peripheral site ligands on the reaction of symmetric and chiral organophosphates with wildtype and mutant acetylcholinesterases.
    Radić Z, Taylor P.
    Chem Biol Interact; 1999 May 14; 119-120():111-7. PubMed ID: 10421444
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  • 15. Interaction of tetrahydroaminoacridine with acetylcholinesterase and butyrylcholinesterase.
    Berman HA, Leonard K.
    Mol Pharmacol; 1992 Feb 14; 41(2):412-8. PubMed ID: 1538717
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  • 17. Fasciculin inhibition of acetylcholinesterase is prevented by chemical modification of the enzyme at a peripheral site.
    Durán R, Cerveñansky C, Dajas F, Tipton KF.
    Biochim Biophys Acta; 1994 Dec 15; 1201(3):381-8. PubMed ID: 7803468
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  • 18. A steric blockade model for inhibition of acetylcholinesterase by peripheral site ligands and substrate.
    Rosenberry TL, Mallender WD, Thomas PJ, Szegletes T.
    Chem Biol Interact; 1999 May 14; 119-120():85-97. PubMed ID: 10421442
    [Abstract] [Full Text] [Related]

  • 19. Does "butyrylization" of acetylcholinesterase through substitution of the six divergent aromatic amino acids in the active center gorge generate an enzyme mimic of butyrylcholinesterase?
    Kaplan D, Ordentlich A, Barak D, Ariel N, Kronman C, Velan B, Shafferman A.
    Biochemistry; 2001 Jun 26; 40(25):7433-45. PubMed ID: 11412096
    [Abstract] [Full Text] [Related]

  • 20. Theoretical and experimental investigations of electrostatic effects on acetylcholinesterase catalysis and inhibition.
    Malany S, Baker N, Verweyst M, Medhekar R, Quinn DM, Velan B, Kronman C, Shafferman A.
    Chem Biol Interact; 1999 May 14; 119-120():99-110. PubMed ID: 10421443
    [Abstract] [Full Text] [Related]

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