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Journal Abstract Search

462 related items for PubMed ID: 22723308

  • 1. EWS/FLI1 regulates EYA3 in Ewing sarcoma via modulation of miRNA-708, resulting in increased cell survival and chemoresistance.
    Robin TP, Smith A, McKinsey E, Reaves L, Jedlicka P, Ford HL.
    Mol Cancer Res; 2012 Aug; 10(8):1098-108. PubMed ID: 22723308
    [Abstract] [Full Text] [Related]

  • 2. MiR-30a-5p connects EWS-FLI1 and CD99, two major therapeutic targets in Ewing tumor.
    Franzetti GA, Laud-Duval K, Bellanger D, Stern MH, Sastre-Garau X, Delattre O.
    Oncogene; 2013 Aug 15; 32(33):3915-21. PubMed ID: 22986530
    [Abstract] [Full Text] [Related]

  • 3. High-throughput RNAi screen in Ewing sarcoma cells identifies leucine rich repeats and WD repeat domain containing 1 (LRWD1) as a regulator of EWS-FLI1 driven cell viability.
    He T, Surdez D, Rantala JK, Haapa-Paananen S, Ban J, Kauer M, Tomazou E, Fey V, Alonso J, Kovar H, Delattre O, Iljin K.
    Gene; 2017 Jan 05; 596():137-146. PubMed ID: 27760381
    [Abstract] [Full Text] [Related]

  • 4. EWS-FLI1 reprograms the metabolism of Ewing sarcoma cells via positive regulation of glutamine import and serine-glycine biosynthesis.
    Sen N, Cross AM, Lorenzi PL, Khan J, Gryder BE, Kim S, Caplen NJ.
    Mol Carcinog; 2018 Oct 05; 57(10):1342-1357. PubMed ID: 29873416
    [Abstract] [Full Text] [Related]

  • 5. EWS-FLI1 regulates a transcriptional program in cooperation with Foxq1 in mouse Ewing sarcoma.
    Shimizu R, Tanaka M, Tsutsumi S, Aburatani H, Yamazaki Y, Homme M, Kitagawa Y, Nakamura T.
    Cancer Sci; 2018 Sep 05; 109(9):2907-2918. PubMed ID: 29945296
    [Abstract] [Full Text] [Related]

  • 6. Selective inhibition of HDAC6 regulates expression of the oncogenic driver EWSR1-FLI1 through the EWSR1 promoter in Ewing sarcoma.
    García-Domínguez DJ, Hajji N, Sánchez-Molina S, Figuerola-Bou E, de Pablos RM, Espinosa-Oliva AM, Andrés-León E, Terrón-Camero LC, Flores-Campos R, Pascual-Pasto G, Robles MJ, Machado I, Llombart-Bosch A, Magagnoli G, Scotlandi K, Carcaboso ÁM, Mora J, de Álava E, Hontecillas-Prieto L.
    Oncogene; 2021 Sep 05; 40(39):5843-5853. PubMed ID: 34345016
    [Abstract] [Full Text] [Related]

  • 7. EWS-FLI1 and Menin Converge to Regulate ATF4 Activity in Ewing Sarcoma.
    Jiménez JA, Apfelbaum AA, Hawkins AG, Svoboda LK, Kumar A, Ruiz RO, Garcia AX, Haarer E, Nwosu ZC, Bradin J, Purohit T, Chen D, Cierpicki T, Grembecka J, Lyssiotis CA, Lawlor ER.
    Mol Cancer Res; 2021 Jul 05; 19(7):1182-1195. PubMed ID: 33741715
    [Abstract] [Full Text] [Related]

  • 8. C/EBPβ-1 promotes transformation and chemoresistance in Ewing sarcoma cells.
    Gardiner JD, Abegglen LM, Huang X, Carter BE, Schackmann EA, Stucki M, Paxton CN, Lor Randall R, Amatruda JF, Putnam AR, Kovar H, Lessnick SL, Schiffman JD.
    Oncotarget; 2017 Apr 18; 8(16):26013-26026. PubMed ID: 28148901
    [Abstract] [Full Text] [Related]

  • 9. Proteasomal Degradation of the EWS-FLI1 Fusion Protein Is Regulated by a Single Lysine Residue.
    Gierisch ME, Pfistner F, Lopez-Garcia LA, Harder L, Schäfer BW, Niggli FK.
    J Biol Chem; 2016 Dec 23; 291(52):26922-26933. PubMed ID: 27875302
    [Abstract] [Full Text] [Related]

  • 10. FOXM1 is an oncogenic mediator in Ewing Sarcoma.
    Christensen L, Joo J, Lee S, Wai D, Triche TJ, May WA.
    PLoS One; 2013 Dec 23; 8(1):e54556. PubMed ID: 23365673
    [Abstract] [Full Text] [Related]

  • 11. Dual targeting of EWS-FLI1 activity and the associated DNA damage response with trabectedin and SN38 synergistically inhibits Ewing sarcoma cell growth.
    Grohar PJ, Segars LE, Yeung C, Pommier Y, D'Incalci M, Mendoza A, Helman LJ.
    Clin Cancer Res; 2014 Mar 01; 20(5):1190-203. PubMed ID: 24277455
    [Abstract] [Full Text] [Related]

  • 12. MiR-193b, downregulated in Ewing Sarcoma, targets the ErbB4 oncogene to inhibit anchorage-independent growth.
    Moore C, Parrish JK, Jedlicka P.
    PLoS One; 2017 Mar 01; 12(5):e0178028. PubMed ID: 28542597
    [Abstract] [Full Text] [Related]

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  • 14. Targeting the EWS-ETS transcriptional program by BET bromodomain inhibition in Ewing sarcoma.
    Hensel T, Giorgi C, Schmidt O, Calzada-Wack J, Neff F, Buch T, Niggli FK, Schäfer BW, Burdach S, Richter GH.
    Oncotarget; 2016 Jan 12; 7(2):1451-63. PubMed ID: 26623725
    [Abstract] [Full Text] [Related]

  • 15. EWS/FLI is a Master Regulator of Metabolic Reprogramming in Ewing Sarcoma.
    Tanner JM, Bensard C, Wei P, Krah NM, Schell JC, Gardiner J, Schiffman J, Lessnick SL, Rutter J.
    Mol Cancer Res; 2017 Nov 12; 15(11):1517-1530. PubMed ID: 28720588
    [Abstract] [Full Text] [Related]

  • 16. Suppression of FOXO1 is responsible for a growth regulatory repressive transcriptional sub-signature of EWS-FLI1 in Ewing sarcoma.
    Niedan S, Kauer M, Aryee DN, Kofler R, Schwentner R, Meier A, Pötschger U, Kontny U, Kovar H.
    Oncogene; 2014 Jul 24; 33(30):3927-38. PubMed ID: 23995784
    [Abstract] [Full Text] [Related]

  • 17. BET bromodomain inhibitors suppress EWS-FLI1-dependent transcription and the IGF1 autocrine mechanism in Ewing sarcoma.
    Loganathan SN, Tang N, Fleming JT, Ma Y, Guo Y, Borinstein SC, Chiang C, Wang J.
    Oncotarget; 2016 Jul 12; 7(28):43504-43517. PubMed ID: 27259270
    [Abstract] [Full Text] [Related]

  • 18. A novel oncogenic mechanism in Ewing sarcoma involving IGF pathway targeting by EWS/Fli1-regulated microRNAs.
    McKinsey EL, Parrish JK, Irwin AE, Niemeyer BF, Kern HB, Birks DK, Jedlicka P.
    Oncogene; 2011 Dec 08; 30(49):4910-20. PubMed ID: 21643012
    [Abstract] [Full Text] [Related]

  • 19. EWS::FLI1 and HOXD13 Control Tumor Cell Plasticity in Ewing Sarcoma.
    Apfelbaum AA, Wu F, Hawkins AG, Magnuson B, Jiménez JA, Taylor SD, Wrenn ED, Waltner O, Pfaltzgraff ER, Song JY, Hall C, Wellik DM, Ljungman M, Furlan SN, Ryan RJH, Sarthy JF, Lawlor ER.
    Clin Cancer Res; 2022 Oct 14; 28(20):4466-4478. PubMed ID: 35653119
    [Abstract] [Full Text] [Related]

  • 20. Loss of Stag2 cooperates with EWS-FLI1 to transform murine Mesenchymal stem cells.
    El Beaino M, Liu J, Wasylishen AR, Pourebrahim R, Migut A, Bessellieu BJ, Huang K, Lin PP.
    BMC Cancer; 2020 Jan 02; 20(1):3. PubMed ID: 31898537
    [Abstract] [Full Text] [Related]

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