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Journal Abstract Search

146 related items for PubMed ID: 22727370

  • 1. Synthesis and structure-activity relationships of benzophenone-bearing diketopiperazine-type anti-microtubule agents.
    Yamazaki Y, Sumikura M, Masuda Y, Hayashi Y, Yasui H, Kiso Y, Chinen T, Usui T, Yakushiji F, Potts B, Neuteboom S, Palladino M, Lloyd GK, Hayashi Y.
    Bioorg Med Chem; 2012 Jul 15; 20(14):4279-89. PubMed ID: 22727370
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and structure-activity relationship study of antimicrotubule agents phenylahistin derivatives with a didehydropiperazine-2,5-dione structure.
    Yamazaki Y, Tanaka K, Nicholson B, Deyanat-Yazdi G, Potts B, Yoshida T, Oda A, Kitagawa T, Orikasa S, Kiso Y, Yasui H, Akamatsu M, Chinen T, Usui T, Shinozaki Y, Yakushiji F, Miller BR, Neuteboom S, Palladino M, Kanoh K, Lloyd GK, Hayashi Y.
    J Med Chem; 2012 Feb 09; 55(3):1056-71. PubMed ID: 22185476
    [Abstract] [Full Text] [Related]

  • 3. Medicinal chemistry and chemical biology of diketopiperazine-type antimicrotubule and vascular-disrupting agents.
    Hayashi Y, Yamazaki-Nakamura Y, Yakushiji F.
    Chem Pharm Bull (Tokyo); 2013 Feb 09; 61(9):889-901. PubMed ID: 23995353
    [Abstract] [Full Text] [Related]

  • 4. Tubulin photoaffinity labeling with biotin-tagged derivatives of potent diketopiperazine antimicrotubule agents.
    Yamazaki Y, Kohno K, Yasui H, Kiso Y, Akamatsu M, Nicholson B, Deyanat-Yazdi G, Neuteboom S, Potts B, Lloyd GK, Hayashi Y.
    Chembiochem; 2008 Dec 15; 9(18):3074-81. PubMed ID: 19012291
    [Abstract] [Full Text] [Related]

  • 5. 2-amino-3,4,5-trimethoxybenzophenones as potent tubulin polymerization inhibitors.
    Chuang HY, Chang JY, Lai MJ, Kuo CC, Lee HY, Hsieh HP, Chen YJ, Chen LT, Pan WY, Liou JP.
    ChemMedChem; 2011 Mar 07; 6(3):450-6. PubMed ID: 21360819
    [Abstract] [Full Text] [Related]

  • 6. Synthesis and biological evaluation of novel anticancer bivalent colchicine-tubulizine hybrids.
    Malysheva YB, Combes S, Allegro D, Peyrot V, Knochel P, Gavryushin AE, Fedorov AY.
    Bioorg Med Chem; 2012 Jul 15; 20(14):4271-8. PubMed ID: 22739088
    [Abstract] [Full Text] [Related]

  • 7. Synthesis of anti-microtubule N-(2-Arylindol-7-yl)benzenesulfonamide derivatives and their antitumor mechanisms.
    Chiou CT, Chen GS, Chen ML, Li H, Shi L, Huang XH, Dai WM, Chern JW.
    ChemMedChem; 2010 Sep 03; 5(9):1489-97. PubMed ID: 20672297
    [No Abstract] [Full Text] [Related]

  • 8. Synthesis and anticancer activity of analogues of phenstatin, with a phenothiazine A-ring, as a new class of microtubule-targeting agents.
    Abuhaie CM, Bîcu E, Rigo B, Gautret P, Belei D, Farce A, Dubois J, Ghinet A.
    Bioorg Med Chem Lett; 2013 Jan 01; 23(1):147-52. PubMed ID: 23200248
    [Abstract] [Full Text] [Related]

  • 9. 5-Amino-2-aroylquinolines as highly potent tubulin polymerization inhibitors.
    Nien CY, Chen YC, Kuo CC, Hsieh HP, Chang CY, Wu JS, Wu SY, Liou JP, Chang JY.
    J Med Chem; 2010 Mar 11; 53(5):2309-13. PubMed ID: 20148562
    [Abstract] [Full Text] [Related]

  • 10. Azides derived from colchicine and their use in library synthesis: A practical entry to new bioactive derivatives of an old natural drug.
    Nicolaus N, Zapke J, Riesterer P, Neudörfl JM, Prokop A, Oschkinat H, Schmalz HG.
    ChemMedChem; 2010 May 03; 5(5):661-5. PubMed ID: 20229567
    [No Abstract] [Full Text] [Related]

  • 11. Design, synthesis and biological evaluation of anti-pancreatic cancer activity of plinabulin derivatives based on the co-crystal structure.
    Fu Z, Hou Y, Ji C, Ma M, Tian Z, Deng M, Zhong L, Chu Y, Li W.
    Bioorg Med Chem; 2018 May 01; 26(8):2061-2072. PubMed ID: 29571653
    [Abstract] [Full Text] [Related]

  • 12. Unsaturated genistein disaccharide glycoside as a novel agent affecting microtubules.
    Rusin A, Gogler A, Głowala-Kosińska M, Bochenek D, Gruca A, Grynkiewicz G, Zawisza J, Szeja W, Krawczyk Z.
    Bioorg Med Chem Lett; 2009 Sep 01; 19(17):4939-43. PubMed ID: 19660945
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and biological evaluation of phenstatin metabolites.
    Ghinet A, Rigo B, Hénichart JP, Le Broc-Ryckewaert D, Pommery J, Pommery N, Thuru X, Quesnel B, Gautret P.
    Bioorg Med Chem; 2011 Oct 15; 19(20):6042-54. PubMed ID: 21920767
    [Abstract] [Full Text] [Related]

  • 14. Synthesis of macrocyclic bisbibenzyl derivatives and their anticancer effects as anti-tubulin agents.
    Jiang J, Sun B, Wang YY, Cui M, Zhang L, Cui CZ, Wang YF, Liu XG, Lou HX.
    Bioorg Med Chem; 2012 Apr 01; 20(7):2382-91. PubMed ID: 22365913
    [Abstract] [Full Text] [Related]

  • 15. 4- and 5-aroylindoles as novel classes of potent antitubulin agents.
    Liou JP, Wu CY, Hsieh HP, Chang CY, Chen CM, Kuo CC, Chang JY.
    J Med Chem; 2007 Sep 06; 50(18):4548-52. PubMed ID: 17685504
    [Abstract] [Full Text] [Related]

  • 16. Development of novel phenoxy-diketopiperazine-type plinabulin derivatives as potent antimicrotubule agents based on the co-crystal structure.
    Ding Z, Ma M, Zhong C, Wang S, Fu Z, Hou Y, Liu Y, Zhong L, Chu Y, Li F, Song C, Wang Y, Yang J, Li W.
    Bioorg Med Chem; 2020 Jan 01; 28(1):115186. PubMed ID: 31759826
    [Abstract] [Full Text] [Related]

  • 17. Computational design and biological testing of highly cytotoxic colchicine ring A modifications.
    Torin Huzil J, Winter P, Johnson L, Weis AL, Bakos T, Banerjee A, Luduena RF, Damaraju S, Tuszynski JA.
    Chem Biol Drug Des; 2010 Jun 01; 75(6):541-50. PubMed ID: 20408852
    [Abstract] [Full Text] [Related]

  • 18. Synthesis and structure-activity relationship of 4-azaheterocycle benzenesulfonamide derivatives as new microtubule-targeting agents.
    Yang J, Zhou S, Ji L, Zhang C, Yu S, Li Z, Meng X.
    Bioorg Med Chem Lett; 2014 Nov 01; 24(21):5055-8. PubMed ID: 25278233
    [Abstract] [Full Text] [Related]

  • 19. Synthesis and SAR requirements of adamantane-colchicine conjugates with both microtubule depolymerizing and tubulin clustering activities.
    Zefirova ON, Nurieva EV, Shishov DV, Baskin II, Fuchs F, Lemcke H, Schröder F, Weiss DG, Zefirov NS, Kuznetsov SA.
    Bioorg Med Chem; 2011 Sep 15; 19(18):5529-38. PubMed ID: 21873068
    [Abstract] [Full Text] [Related]

  • 20. Biological evaluation and molecular modelling study of podophyllotoxin derivatives as potent inhibitors of tubulin polymerization.
    Ma Y, Fang S, Li H, Han C, Lu Y, Zhao Y, Liu Y, Zhao C.
    Chem Biol Drug Des; 2013 Jul 15; 82(1):12-21. PubMed ID: 23786349
    [Abstract] [Full Text] [Related]

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