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260 related items for PubMed ID: 22736376

  • 1. ¹¹¹In-Bn-DTPA-nimotuzumab with/without modification with nuclear translocation sequence (NLS) peptides: an Auger electron-emitting radioimmunotherapeutic agent for EGFR-positive and trastuzumab (Herceptin)-resistant breast cancer.
    Fasih A, Fonge H, Cai Z, Leyton JV, Tikhomirov I, Done SJ, Reilly RM.
    Breast Cancer Res Treat; 2012 Aug; 135(1):189-200. PubMed ID: 22736376
    [Abstract] [Full Text] [Related]

  • 2. Effectiveness and normal tissue toxicity of Auger electron (AE) radioimmunotherapy (RIT) with [111In]In-Bn-DTPA-nimotuzumab in mice with triple-negative or trastuzumab-resistant human breast cancer xenografts that overexpress EGFR.
    Chan C, Fonge H, Lam K, Reilly RM.
    Nucl Med Biol; 2020 Aug; 80-81():37-44. PubMed ID: 31706737
    [Abstract] [Full Text] [Related]

  • 3. (111)In-labeled trastuzumab (Herceptin) modified with nuclear localization sequences (NLS): an Auger electron-emitting radiotherapeutic agent for HER2/neu-amplified breast cancer.
    Costantini DL, Chan C, Cai Z, Vallis KA, Reilly RM.
    J Nucl Med; 2007 Aug; 48(8):1357-68. PubMed ID: 17631548
    [Abstract] [Full Text] [Related]

  • 4. Dual-Receptor-Targeted Radioimmunotherapy of Human Breast Cancer Xenografts in Athymic Mice Coexpressing HER2 and EGFR Using 177Lu- or 111In-Labeled Bispecific Radioimmunoconjugates.
    Razumienko EJ, Chen JC, Cai Z, Chan C, Reilly RM.
    J Nucl Med; 2016 Mar; 57(3):444-52. PubMed ID: 26429962
    [Abstract] [Full Text] [Related]

  • 5. Multifunctional block copolymer micelles for the delivery of 111In to EGFR-positive breast cancer cells for targeted Auger electron radiotherapy.
    Fonge H, Lee H, Reilly RM, Allen C.
    Mol Pharm; 2010 Feb 01; 7(1):177-86. PubMed ID: 19924993
    [Abstract] [Full Text] [Related]

  • 6. A comparison of non-biologically active truncated EGF (EGFt) and full-length hEGF for delivery of Auger electron-emitting 111In to EGFR-positive breast cancer cells and tumor xenografts in athymic mice.
    Panosa C, Fonge H, Ferrer-Batallé M, Menéndez JA, Massaguer A, De Llorens R, Reilly RM.
    Nucl Med Biol; 2015 Dec 01; 42(12):931-8. PubMed ID: 26385534
    [Abstract] [Full Text] [Related]

  • 7. Antitumor effects and normal tissue toxicity of 111In-labeled epidermal growth factor administered to athymic mice bearing epidermal growth factor receptor-positive human breast cancer xenografts.
    Chen P, Cameron R, Wang J, Vallis KA, Reilly RM.
    J Nucl Med; 2003 Sep 01; 44(9):1469-78. PubMed ID: 12960194
    [Abstract] [Full Text] [Related]

  • 8. Trastuzumab Labeled to High Specific Activity with (111)In by Site-Specific Conjugation to a Metal-Chelating Polymer Exhibits Amplified Auger Electron-Mediated Cytotoxicity on HER2-Positive Breast Cancer Cells.
    Ngo Ndjock Mbong G, Lu Y, Chan C, Cai Z, Liu P, Boyle AJ, Winnik MA, Reilly RM.
    Mol Pharm; 2015 Jun 01; 12(6):1951-60. PubMed ID: 25919639
    [Abstract] [Full Text] [Related]

  • 9. Trastuzumab-resistant breast cancer cells remain sensitive to the auger electron-emitting radiotherapeutic agent 111In-NLS-trastuzumab and are radiosensitized by methotrexate.
    Costantini DL, Bateman K, McLarty K, Vallis KA, Reilly RM.
    J Nucl Med; 2008 Sep 01; 49(9):1498-505. PubMed ID: 18703606
    [Abstract] [Full Text] [Related]

  • 10. 111In-labeled EGF is selectively radiotoxic to human breast cancer cells overexpressing EGFR.
    Reilly RM, Kiarash R, Cameron RG, Porlier N, Sandhu J, Hill RP, Vallis K, Hendler A, Gariépy J.
    J Nucl Med; 2000 Mar 01; 41(3):429-38. PubMed ID: 10716315
    [Abstract] [Full Text] [Related]

  • 11. 111In- or 99mTc-labeled recombinant VEGF bioconjugates: in vitro evaluation of their cytotoxicity on porcine aortic endothelial cells overexpressing Flt-1 receptors.
    Chan C, Cai Z, Su R, Reilly RM.
    Nucl Med Biol; 2010 Feb 01; 37(2):105-15. PubMed ID: 20152709
    [Abstract] [Full Text] [Related]

  • 12. Methotrexate, paclitaxel, and doxorubicin radiosensitize HER2-amplified human breast cancer cells to the Auger electron-emitting radiotherapeutic agent (111)In-NLS-trastuzumab.
    Costantini DL, Villani DF, Vallis KA, Reilly RM.
    J Nucl Med; 2010 Mar 01; 51(3):477-83. PubMed ID: 20150272
    [Abstract] [Full Text] [Related]

  • 13. Preclinical evaluation of (177)lu-nimotuzumab: a potential tool for radioimmunotherapy of epidermal growth factor receptor-overexpressing tumors.
    Vera DR, Eigner S, Beran M, Henke KE, Laznickova A, Laznicek M, Melichar F, Chinol M.
    Cancer Biother Radiopharm; 2011 Jun 01; 26(3):287-97. PubMed ID: 21711096
    [Abstract] [Full Text] [Related]

  • 14. 111In-labeled immunoconjugates (ICs) bispecific for the epidermal growth factor receptor (EGFR) and cyclin-dependent kinase inhibitor, p27Kip1.
    Cornelissen B, Kersemans V, McLarty K, Tran L, Reilly RM.
    Cancer Biother Radiopharm; 2009 Apr 01; 24(2):163-73. PubMed ID: 19409037
    [Abstract] [Full Text] [Related]

  • 15. MicroSPECT/CT imaging of co-expressed HER2 and EGFR on subcutaneous human tumor xenografts in athymic mice using ¹¹¹In-labeled bispecific radioimmunoconjugates.
    Razumienko E, Dryden L, Scollard D, Reilly RM.
    Breast Cancer Res Treat; 2013 Apr 01; 138(3):709-18. PubMed ID: 23525982
    [Abstract] [Full Text] [Related]

  • 16. Antitumor effects and normal-tissue toxicity of 111In-nuclear localization sequence-trastuzumab in athymic mice bearing HER-positive human breast cancer xenografts.
    Costantini DL, McLarty K, Lee H, Done SJ, Vallis KA, Reilly RM.
    J Nucl Med; 2010 Jul 01; 51(7):1084-91. PubMed ID: 20554744
    [Abstract] [Full Text] [Related]

  • 17. Auger electron-emitting (111)In-DTPA-NLS-CSL360 radioimmunoconjugates are cytotoxic to human acute myeloid leukemia (AML) cells displaying the CD123(+)/CD131(-) phenotype of leukemia stem cells.
    Gao C, Leyton JV, Schimmer AD, Minden M, Reilly RM.
    Appl Radiat Isot; 2016 Apr 01; 110():1-7. PubMed ID: 26748017
    [Abstract] [Full Text] [Related]

  • 18. Block copolymer micelles target Auger electron radiotherapy to the nucleus of HER2-positive breast cancer cells.
    Hoang B, Reilly RM, Allen C.
    Biomacromolecules; 2012 Feb 13; 13(2):455-65. PubMed ID: 22191486
    [Abstract] [Full Text] [Related]

  • 19. Conjugation with (111)In-DTPA-poly(ethylene glycol) improves imaging of anti-EGF receptor antibody C225.
    Wen X, Wu QP, Ke S, Ellis L, Charnsangavej C, Delpassand AS, Wallace S, Li C.
    J Nucl Med; 2001 Oct 13; 42(10):1530-7. PubMed ID: 11585869
    [Abstract] [Full Text] [Related]

  • 20. A comparison of EGF and MAb 528 labeled with 111In for imaging human breast cancer.
    Reilly RM, Kiarash R, Sandhu J, Lee YW, Cameron RG, Hendler A, Vallis K, Gariépy J.
    J Nucl Med; 2000 May 13; 41(5):903-11. PubMed ID: 10809207
    [Abstract] [Full Text] [Related]

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