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912 related items for PubMed ID: 22740515

  • 1. Cyclic GMP/protein kinase G type-Iα (PKG-Iα) signaling pathway promotes CREB phosphorylation and maintains higher c-IAP1, livin, survivin, and Mcl-1 expression and the inhibition of PKG-Iα kinase activity synergizes with cisplatin in non-small cell lung cancer cells.
    Wong JC, Bathina M, Fiscus RR.
    J Cell Biochem; 2012 Nov; 113(11):3587-98. PubMed ID: 22740515
    [Abstract] [Full Text] [Related]

  • 2. Protein kinase G type Ialpha activity in human ovarian cancer cells significantly contributes to enhanced Src activation and DNA synthesis/cell proliferation.
    Leung EL, Wong JC, Johlfs MG, Tsang BK, Fiscus RR.
    Mol Cancer Res; 2010 Apr; 8(4):578-91. PubMed ID: 20371672
    [Abstract] [Full Text] [Related]

  • 3. Essential roles of the nitric oxide (no)/cGMP/protein kinase G type-Iα (PKG-Iα) signaling pathway and the atrial natriuretic peptide (ANP)/cGMP/PKG-Iα autocrine loop in promoting proliferation and cell survival of OP9 bone marrow stromal cells.
    Wong JC, Fiscus RR.
    J Cell Biochem; 2011 Mar; 112(3):829-39. PubMed ID: 21328456
    [Abstract] [Full Text] [Related]

  • 4. Protein kinase G type-Ialpha phosphorylates the apoptosis-regulating protein Bad at serine 155 and protects against apoptosis in N1E-115 cells.
    Johlfs MG, Fiscus RR.
    Neurochem Int; 2010 Mar; 56(4):546-53. PubMed ID: 20043968
    [Abstract] [Full Text] [Related]

  • 5. Expression of livin in gastric cancer and induction of apoptosis in SGC-7901 cells by shRNA-mediated silencing of livin gene.
    Wang TS, Ding QQ, Guo RH, Shen H, Sun J, Lu KH, You SH, Ge HM, Shu YQ, Liu P.
    Biomed Pharmacother; 2010 May; 64(5):333-8. PubMed ID: 19914791
    [Abstract] [Full Text] [Related]

  • 6. Expression and role of the inhibitor of apoptosis protein livin in chemotherapy sensitivity of ovarian carcinoma.
    Liu X, Wang A, Gao H, Yuan Z, Jiao Y.
    Int J Oncol; 2012 Sep; 41(3):1021-8. PubMed ID: 22766624
    [Abstract] [Full Text] [Related]

  • 7. [Expression of livin in gastric cancer and effect of silencing of the livin gene on apoptosis in gastric cancer cells].
    Liu P, Wang TS, You SH, Ge HM.
    Zhonghua Zhong Liu Za Zhi; 2007 Aug; 29(8):570-4. PubMed ID: 18210873
    [Abstract] [Full Text] [Related]

  • 8. Pancreatic-β-cell survival and proliferation are promoted by protein kinase G type Iα and downstream regulation of AKT/FOXO1.
    Wong JC, Vo V, Gorjala P, Fiscus RR.
    Diab Vasc Dis Res; 2017 Sep; 14(5):434-449. PubMed ID: 28631500
    [Abstract] [Full Text] [Related]

  • 9. cAMP-responsive element binding protein mediates a cGMP/protein kinase G-dependent anti-apoptotic signal induced by nitric oxide in retinal neuro-glial progenitor cells.
    Nagai-Kusuhara A, Nakamura M, Mukuno H, Kanamori A, Negi A, Seigel GM.
    Exp Eye Res; 2007 Jan; 84(1):152-62. PubMed ID: 17081519
    [Abstract] [Full Text] [Related]

  • 10. The anti-apoptotic livin gene is an important determinant for the apoptotic resistance of non-small cell lung cancer cells.
    Crnković-Mertens I, Muley T, Meister M, Hartenstein B, Semzow J, Butz K, Hoppe-Seyler F.
    Lung Cancer; 2006 Nov; 54(2):135-42. PubMed ID: 16965834
    [Abstract] [Full Text] [Related]

  • 11. Expression of survivin mRNA and livin mRNA in non-small-cell lung cancer.
    Tanabe H, Yagihashi A, Tsuji N, Shijubo Y, Abe S, Watanabe N.
    Lung Cancer; 2004 Dec; 46(3):299-304. PubMed ID: 15541814
    [Abstract] [Full Text] [Related]

  • 12. Emodin enhances cisplatin-induced cytotoxicity via down-regulation of ERCC1 and inactivation of ERK1/2.
    Ko JC, Su YJ, Lin ST, Jhan JY, Ciou SC, Cheng CM, Chiu YF, Kuo YH, Tsai MS, Lin YW.
    Lung Cancer; 2010 Aug; 69(2):155-64. PubMed ID: 19962780
    [Abstract] [Full Text] [Related]

  • 13. Resveratrol at anti-angiogenesis/anticancer concentrations suppresses protein kinase G signaling and decreases IAPs expression in HUVECs.
    Wong JC, Fiscus RR.
    Anticancer Res; 2015 Jan; 35(1):273-81. PubMed ID: 25550561
    [Abstract] [Full Text] [Related]

  • 14. Protein kinase G activity prevents pathological-level nitric oxide-induced apoptosis and promotes DNA synthesis/cell proliferation in vascular smooth muscle cells.
    Wong JC, Fiscus RR.
    Cardiovasc Pathol; 2010 Jan; 19(6):e221-31. PubMed ID: 20060325
    [Abstract] [Full Text] [Related]

  • 15. Defects in apoptotic signal transduction in cisplatin-resistant non-small cell lung cancer cells.
    Ikuta K, Takemura K, Kihara M, Naito S, Lee E, Shimizu E, Yamauchi A.
    Oncol Rep; 2005 Jun; 13(6):1229-34. PubMed ID: 15870947
    [Abstract] [Full Text] [Related]

  • 16. Roles of BIM induction and survivin downregulation in lapatinib-induced apoptosis in breast cancer cells with HER2 amplification.
    Tanizaki J, Okamoto I, Fumita S, Okamoto W, Nishio K, Nakagawa K.
    Oncogene; 2011 Sep 29; 30(39):4097-106. PubMed ID: 21499301
    [Abstract] [Full Text] [Related]

  • 17. Effects of Livin gene RNA interference on apoptosis of cervical cancer HeLa cells and enhanced sensitivity to cisplatin.
    Yu L, Wang Z.
    J Huazhong Univ Sci Technolog Med Sci; 2009 Oct 29; 29(5):625-30. PubMed ID: 19821098
    [Abstract] [Full Text] [Related]

  • 18. Silencing Livin induces apoptotic and autophagic cell death, increasing chemotherapeutic sensitivity to cisplatin of renal carcinoma cells.
    Wang Z, Liu S, Ding K, Ding S, Li C, Lu J, Gao D, Zhang T, Bi D.
    Tumour Biol; 2016 Nov 29; 37(11):15133-15143. PubMed ID: 27677286
    [Abstract] [Full Text] [Related]

  • 19. Livin mediates tumor cell invasion in the DU-145 cell line via NF-κB.
    Chen F, Yang D, Che X, Wang J, Li X, Zhang Z, Chen X, Song X.
    Oncol Rep; 2012 Jun 29; 27(6):2010-6. PubMed ID: 22427141
    [Abstract] [Full Text] [Related]

  • 20. Role of XIAP in inhibiting cisplatin-induced caspase activation in non-small cell lung cancer cells: a small molecule Smac mimic sensitizes for chemotherapy-induced apoptosis by enhancing caspase-3 activation.
    Checinska A, Hoogeland BS, Rodriguez JA, Giaccone G, Kruyt FA.
    Exp Cell Res; 2007 Apr 01; 313(6):1215-24. PubMed ID: 17291493
    [Abstract] [Full Text] [Related]

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