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290 related items for PubMed ID: 22749977

  • 1. An antioxidant Trolox restores decreased oral absorption of cyclosporine A after liver ischemia-reperfusion through distinct mechanisms between CYP3A and P-glycoprotein in the small intestine.
    Ikemura K, Inoue K, Mizutani H, Oka H, Iwamoto T, Okuda M.
    Eur J Pharmacol; 2012 Sep 05; 690(1-3):192-201. PubMed ID: 22749977
    [Abstract] [Full Text] [Related]

  • 2. Decreased oral absorption of cyclosporine A after liver ischemia-reperfusion injury in rats: the contribution of CYP3A and P-glycoprotein to the first-pass metabolism in intestinal epithelial cells.
    Ikemura K, Urano K, Matsuda H, Mizutani H, Iwamoto T, Okuda M.
    J Pharmacol Exp Ther; 2009 Jan 05; 328(1):249-55. PubMed ID: 18842703
    [Abstract] [Full Text] [Related]

  • 3. Decrease in oral bioavailability of ciclosporin by intravenous pulse of methylprednisolone succinate in rats.
    Konishi H, Sumi M, Shibata N, Takada K, Minouchi T, Yamaji A.
    J Pharm Pharmacol; 2004 Oct 05; 56(10):1259-66. PubMed ID: 15482640
    [Abstract] [Full Text] [Related]

  • 4. Renoprotective effect of trolox against ischaemia-reperfusion injury in rats.
    Wongmekiat O, Thamprasert K, Lumlertgul D.
    Clin Exp Pharmacol Physiol; 2007 Aug 05; 34(8):753-9. PubMed ID: 17600552
    [Abstract] [Full Text] [Related]

  • 5. Contribution of down-regulation of intestinal and hepatic cytochrome P450 3A to increased absorption of cyclosporine A in a rat nephrosis model.
    Fujita T, Yasuda S, Kamata Y, Fujita K, Ohtani Y, Kumagai Y, Majima M.
    J Pharmacol Exp Ther; 2008 Nov 05; 327(2):592-9. PubMed ID: 18725544
    [Abstract] [Full Text] [Related]

  • 6. Limited interaction between tacrolimus and P-glycoprotein in the rat small intestine.
    Saitoh H, Saikachi Y, Kobayashi M, Yamaguchi M, Oda M, Yuhki Y, Achiwa K, Tadano K, Takahashi Y, Aungst BJ.
    Eur J Pharm Sci; 2006 May 05; 28(1-2):34-42. PubMed ID: 16457995
    [Abstract] [Full Text] [Related]

  • 7. Effects of liver fibrosis on verapamil pharmacokinetics in rats.
    Chen M, Xu D, Hu XL, Wang H.
    Clin Exp Pharmacol Physiol; 2008 Mar 05; 35(3):287-94. PubMed ID: 17973928
    [Abstract] [Full Text] [Related]

  • 8. Pharmacokinetic interaction of cytochrome P450 3A-related compounds with rhodamine 123, a P-glycoprotein substrate, in rats pretreated with dexamethasone.
    Yumoto R, Murakami T, Sanemasa M, Nasu R, Nagai J, Takano M.
    Drug Metab Dispos; 2001 Feb 05; 29(2):145-51. PubMed ID: 11159804
    [Abstract] [Full Text] [Related]

  • 9. Impact of curcumin-induced changes in P-glycoprotein and CYP3A expression on the pharmacokinetics of peroral celiprolol and midazolam in rats.
    Zhang W, Tan TM, Lim LY.
    Drug Metab Dispos; 2007 Jan 05; 35(1):110-5. PubMed ID: 17050652
    [Abstract] [Full Text] [Related]

  • 10. Demonstration of docosahexaenoic acid as a bioavailability enhancer for CYP3A substrates: in vitro and in vivo evidence using cyclosporin in rats.
    Hirunpanich V, Katagi J, Sethabouppha B, Sato H.
    Drug Metab Dispos; 2006 Feb 05; 34(2):305-10. PubMed ID: 16299163
    [Abstract] [Full Text] [Related]

  • 11. Dextran sulfate sodium-induced colitis and ginseng intervention altered oral pharmacokinetics of cyclosporine A in rats.
    Yang Y, Hu N, Gao XJ, Li T, Yan ZX, Wang PP, Wei B, Li S, Zhang ZJ, Li SL, Yan R.
    J Ethnopharmacol; 2021 Jan 30; 265():113251. PubMed ID: 32810615
    [Abstract] [Full Text] [Related]

  • 12. Alpha-lipoic acid protects against hepatic ischemia-reperfusion injury in rats.
    Dulundu E, Ozel Y, Topaloglu U, Sehirli O, Ercan F, Gedik N, Sener G.
    Pharmacology; 2007 Jan 30; 79(3):163-70. PubMed ID: 17259747
    [Abstract] [Full Text] [Related]

  • 13. Prophylaxis with mesna prevents oxidative stress induced by ischemia reperfusion in the intestine via inhibition of nuclear factor-kappaB activation.
    Ypsilantis P, Tentes I, Lambropoulou M, Anagnostopoulos K, Papadopoulos N, Kortsaris A, Simopoulos C.
    J Gastroenterol Hepatol; 2008 Feb 30; 23(2):328-35. PubMed ID: 17868332
    [Abstract] [Full Text] [Related]

  • 14. Effects of peripherally and centrally applied ghrelin in the pathogenesis of ischemia-reperfusion induced injury of the small intestine.
    Pawlik MW, Obuchowicz R, Biernat J, Szczepanski W, Pajdo R, Kwiecień S, Brzozowski T, Konturek SJ, Pawlik WW.
    J Physiol Pharmacol; 2011 Aug 30; 62(4):429-39. PubMed ID: 22100844
    [Abstract] [Full Text] [Related]

  • 15. MicroRNA-145 post-transcriptionally regulates the expression and function of P-glycoprotein in intestinal epithelial cells.
    Ikemura K, Yamamoto M, Miyazaki S, Mizutani H, Iwamoto T, Okuda M.
    Mol Pharmacol; 2013 Feb 30; 83(2):399-405. PubMed ID: 23166305
    [Abstract] [Full Text] [Related]

  • 16. Baicalin reduces ciclosporin bioavailability by inducing intestinal p-glycoprotein in rats.
    Tian X, Chang Y, Wei J, Liu R, Wang L, Zhang J, Zhang X.
    J Pharm Pharmacol; 2019 May 30; 71(5):788-796. PubMed ID: 30663770
    [Abstract] [Full Text] [Related]

  • 17. Effect of prototypical inducing agents on P-glycoprotein and CYP3A expression in mouse tissues.
    Matheny CJ, Ali RY, Yang X, Pollack GM.
    Drug Metab Dispos; 2004 Sep 30; 32(9):1008-14. PubMed ID: 15319343
    [Abstract] [Full Text] [Related]

  • 18. Effects of Trolox on the activity and gene expression of cytochrome P450 in hepatic ischemia/reperfusion.
    Eum HA, Lee SM.
    Br J Pharmacol; 2004 May 30; 142(1):35-42. PubMed ID: 15051625
    [Abstract] [Full Text] [Related]

  • 19. P-glycoprotein increases portal bioavailability of loperamide in mouse by reducing first-pass intestinal metabolism.
    Dufek MB, Knight BM, Bridges AS, Thakker DR.
    Drug Metab Dispos; 2013 Mar 30; 41(3):642-50. PubMed ID: 23288866
    [Abstract] [Full Text] [Related]

  • 20. Effects of scutellarin on liver function after brain ischemia/reperfusion in rats.
    Yang XF, He W, Lu WH, Zeng FD.
    Acta Pharmacol Sin; 2003 Nov 30; 24(11):1118-24. PubMed ID: 14627496
    [Abstract] [Full Text] [Related]

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