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Journal Abstract Search

524 related items for PubMed ID: 22760069

  • 1. Anti-diabetic and anti-adipogenic effects of a novel selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor in the diet-induced obese mice.
    Park JS, Rhee SD, Jung WH, Kang NS, Kim HY, Kang SK, Ahn JH, Kim KY.
    Eur J Pharmacol; 2012 Sep 15; 691(1-3):19-27. PubMed ID: 22760069
    [Abstract] [Full Text] [Related]

  • 2. Anti-diabetic and anti-inflammatory effect of a novel selective 11β-HSD1 inhibitor in the diet-induced obese mice.
    Park SB, Jung WH, Kang NS, Park JS, Bae GH, Kim HY, Rhee SD, Kang SK, Ahn JH, Jeong HG, Kim KY.
    Eur J Pharmacol; 2013 Dec 05; 721(1-3):70-9. PubMed ID: 24135201
    [Abstract] [Full Text] [Related]

  • 3. Anti-diabetic and anti-adipogenic effects of a novel selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor, 2-(3-benzoyl)-4-hydroxy-1,1-dioxo-2H-1,2-benzothiazine-2-yl-1-phenylethanone (KR-66344).
    Park JS, Rhee SD, Kang NS, Jung WH, Kim HY, Kim JH, Kang SK, Cheon HG, Ahn JH, Kim KY.
    Biochem Pharmacol; 2011 Apr 15; 81(8):1028-35. PubMed ID: 21315688
    [Abstract] [Full Text] [Related]

  • 4. A novel 11β-HSD1 inhibitor improves diabesity and osteoblast differentiation.
    Park JS, Bae SJ, Choi SW, Son YH, Park SB, Rhee SD, Kim HY, Jung WH, Kang SK, Ahn JH, Kim SH, Kim KY.
    J Mol Endocrinol; 2014 Apr 15; 52(2):191-202. PubMed ID: 24444497
    [Abstract] [Full Text] [Related]

  • 5. HIS-388, a novel orally active and long-acting 11β-hydroxysteroid dehydrogenase type 1 inhibitor, ameliorates insulin sensitivity and glucose intolerance in diet-induced obesity and nongenetic type 2 diabetic murine models.
    Okazaki S, Takahashi T, Iwamura T, Nakaki J, Sekiya Y, Yagi M, Kumagai H, Sato M, Sakami S, Nitta A, Kawai K, Kainoh M.
    J Pharmacol Exp Ther; 2014 Oct 15; 351(1):181-9. PubMed ID: 25100752
    [Abstract] [Full Text] [Related]

  • 6. Identification of a novel 11β-HSD1 inhibitor from a high-throughput screen of natural product extracts.
    Park SB, Park JS, Jung WH, Park A, Jo SR, Kim HY, Dal Rhee S, Ryu SY, Jeong HG, Park S, Lee H, Kim KY.
    Pharmacol Res; 2015 Dec 15; 102():245-53. PubMed ID: 26515507
    [Abstract] [Full Text] [Related]

  • 7. A novel highly potent and selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor, UI-1499.
    Byun SY, Shin YJ, Nam KY, Hong SP, Ahn SK.
    Life Sci; 2015 Jan 01; 120():1-7. PubMed ID: 25447448
    [Abstract] [Full Text] [Related]

  • 8. Inhibition of 11β-hydroxysteroid dehydrogenase 1 by carbenoxolone affects glucose homeostasis and obesity in db/db mice.
    Dhanesha N, Joharapurkar A, Shah G, Kshirsagar S, Dhote V, Sharma A, Jain M.
    Clin Exp Pharmacol Physiol; 2012 Jan 01; 39(1):69-77. PubMed ID: 22060140
    [Abstract] [Full Text] [Related]

  • 9. Glucocorticoids and 11beta-hydroxysteroid dehydrogenase type 1 in obesity and the metabolic syndrome.
    Stimson RH, Walker BR.
    Minerva Endocrinol; 2007 Sep 01; 32(3):141-59. PubMed ID: 17912154
    [Abstract] [Full Text] [Related]

  • 10. Inhibitors of 11β-hydroxysteroid dehydrogenase type 1 in antidiabetic therapy.
    Wang M.
    Handb Exp Pharmacol; 2011 Sep 01; (203):127-46. PubMed ID: 21484570
    [Abstract] [Full Text] [Related]

  • 11. Emodin, an 11β-hydroxysteroid dehydrogenase type 1 inhibitor, regulates adipocyte function in vitro and exerts anti-diabetic effect in ob/ob mice.
    Wang YJ, Huang SL, Feng Y, Ning MM, Leng Y.
    Acta Pharmacol Sin; 2012 Sep 01; 33(9):1195-203. PubMed ID: 22922341
    [Abstract] [Full Text] [Related]

  • 12. A novel highly potent and selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor, INU-101.
    Hong SP, Han D, Chang KH, Ahn SK.
    Eur J Pharmacol; 2018 Sep 15; 835():169-178. PubMed ID: 30096297
    [Abstract] [Full Text] [Related]

  • 13. Efficacious 11beta-hydroxysteroid dehydrogenase type I inhibitors in the diet-induced obesity mouse model.
    Wan ZK, Chenail E, Xiang J, Li HQ, Ipek M, Bard J, Svenson K, Mansour TS, Xu X, Tian X, Suri V, Hahm S, Xing Y, Johnson CE, Li X, Qadri A, Panza D, Perreault M, Tobin JF, Saiah E.
    J Med Chem; 2009 Sep 10; 52(17):5449-61. PubMed ID: 19673466
    [Abstract] [Full Text] [Related]

  • 14. 2-amino-1,3-thiazol-4(5H)-ones as potent and selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitors: enzyme-ligand co-crystal structure and demonstration of pharmacodynamic effects in C57Bl/6 mice.
    Johansson L, Fotsch C, Bartberger MD, Castro VM, Chen M, Emery M, Gustafsson S, Hale C, Hickman D, Homan E, Jordan SR, Komorowski R, Li A, McRae K, Moniz G, Matsumoto G, Orihuela C, Palm G, Veniant M, Wang M, Williams M, Zhang J.
    J Med Chem; 2008 May 22; 51(10):2933-43. PubMed ID: 18419108
    [Abstract] [Full Text] [Related]

  • 15. 11beta-HSD1 inhibition ameliorates metabolic syndrome and prevents progression of atherosclerosis in mice.
    Hermanowski-Vosatka A, Balkovec JM, Cheng K, Chen HY, Hernandez M, Koo GC, Le Grand CB, Li Z, Metzger JM, Mundt SS, Noonan H, Nunes CN, Olson SH, Pikounis B, Ren N, Robertson N, Schaeffer JM, Shah K, Springer MS, Strack AM, Strowski M, Wu K, Wu T, Xiao J, Zhang BB, Wright SD, Thieringer R.
    J Exp Med; 2005 Aug 15; 202(4):517-27. PubMed ID: 16103409
    [Abstract] [Full Text] [Related]

  • 16. Pharmacological evaluation of adipose dysfunction via 11β-hydroxysteroid dehydrogenase type 1 in the development of diabetes in diet-induced obese mice with cortisone pellet implantation.
    Akiyama N, Akiyama Y, Kato H, Kuroda T, Ono T, Imagawa K, Asakura K, Shinosaki T, Murayama T, Hanasaki K.
    J Pharmacol Exp Ther; 2014 Apr 15; 349(1):66-74. PubMed ID: 24511146
    [Abstract] [Full Text] [Related]

  • 17. Suppression of 11beta-hydroxysteroid dehydrogenase type 1 with RNA interference substantially attenuates 3T3-L1 adipogenesis.
    Liu Y, Park F, Pietrusz JL, Jia G, Singh RJ, Netzel BC, Liang M.
    Physiol Genomics; 2008 Feb 19; 32(3):343-51. PubMed ID: 18073273
    [Abstract] [Full Text] [Related]

  • 18. 11beta-hydroxysteroid dehydrogenase type 1 and obesity.
    Morton NM, Seckl JR.
    Front Horm Res; 2008 Feb 19; 36():146-164. PubMed ID: 18230901
    [Abstract] [Full Text] [Related]

  • 19. A Novel Selective 11β-HSD1 Inhibitor, (E)-4-(2-(6-(2,6-Dichloro-4-(Trifluoromethyl)Phenyl)-4-Methyl-1,1-Dioxido-1,2,6-Thiadiazinan-2-yl)Acetamido)Adamantan-1-Carboxamide (KR-67607), Prevents BAC-Induced Dry Eye Syndrome.
    Na YJ, Choi KJ, Jung WH, Park SB, Kang S, Ahn JH, Kim KY.
    Int J Mol Sci; 2020 May 25; 21(10):. PubMed ID: 32466320
    [Abstract] [Full Text] [Related]

  • 20. Bezafibrate regulates the expression and enzyme activity of 11beta-hydroxysteroid dehydrogenase type 1 in murine adipose tissue and 3T3-L1 adipocytes.
    Nakano S, Inada Y, Masuzaki H, Tanaka T, Yasue S, Ishii T, Arai N, Ebihara K, Hosoda K, Maruyama K, Yamazaki Y, Shibata N, Nakao K.
    Am J Physiol Endocrinol Metab; 2007 Apr 25; 292(4):E1213-22. PubMed ID: 17190905
    [Abstract] [Full Text] [Related]

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