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Journal Abstract Search

155 related items for PubMed ID: 22761275

  • 1. The DPP4 inhibitor linagliptin delays the onset of diabetes and preserves β-cell mass in non-obese diabetic mice.
    Jelsing J, Vrang N, van Witteloostuijn SB, Mark M, Klein T.
    J Endocrinol; 2012 Sep; 214(3):381-7. PubMed ID: 22761275
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  • 4. Linagliptin enhances neural stem cell proliferation after stroke in type 2 diabetic mice.
    Darsalia V, Olverling A, Larsson M, Mansouri S, Nathanson D, Nyström T, Klein T, Sjöholm Å, Patrone C.
    Regul Pept; 2014 May; 190-191():25-31. PubMed ID: 24821550
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  • 5. Linagliptin-mediated DPP-4 inhibition ameliorates kidney fibrosis in streptozotocin-induced diabetic mice by inhibiting endothelial-to-mesenchymal transition in a therapeutic regimen.
    Kanasaki K, Shi S, Kanasaki M, He J, Nagai T, Nakamura Y, Ishigaki Y, Kitada M, Srivastava SP, Koya D.
    Diabetes; 2014 Jun; 63(6):2120-31. PubMed ID: 24574044
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  • 7. Reversal of new-onset diabetes through modulating inflammation and stimulating beta-cell replication in nonobese diabetic mice by a dipeptidyl peptidase IV inhibitor.
    Tian L, Gao J, Hao J, Zhang Y, Yi H, O'Brien TD, Sorenson R, Luo J, Guo Z.
    Endocrinology; 2010 Jul; 151(7):3049-60. PubMed ID: 20444936
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  • 10. Binding to dipeptidyl peptidase-4 determines the disposition of linagliptin (BI 1356)--investigations in DPP-4 deficient and wildtype rats.
    Retlich S, Withopf B, Greischel A, Staab A, Jaehde U, Fuchs H.
    Biopharm Drug Dispos; 2009 Nov; 30(8):422-36. PubMed ID: 19771584
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  • 11. Selective pharmacological inhibition of phosphoinositide 3-kinase p110delta opposes the progression of autoimmune diabetes in non-obese diabetic (NOD) mice.
    Durand CA, Richer MJ, Brenker K, Graves M, Shanina I, Choi K, Horwitz MS, Puri KD, Gold MR.
    Autoimmunity; 2013 Feb; 46(1):62-73. PubMed ID: 23039284
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  • 12. Excretion of the dipeptidyl peptidase-4 inhibitor linagliptin in rats is primarily by biliary excretion and P-gp-mediated efflux.
    Fuchs H, Runge F, Held HD.
    Eur J Pharm Sci; 2012 Apr 11; 45(5):533-8. PubMed ID: 22198311
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  • 13. Linagliptin, a dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes.
    Tiwari A.
    Curr Opin Investig Drugs; 2009 Oct 11; 10(10):1091-104. PubMed ID: 19777398
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  • 14. Glucose-independent improvement of vascular dysfunction in experimental sepsis by dipeptidyl-peptidase 4 inhibition.
    Kröller-Schön S, Knorr M, Hausding M, Oelze M, Schuff A, Schell R, Sudowe S, Scholz A, Daub S, Karbach S, Kossmann S, Gori T, Wenzel P, Schulz E, Grabbe S, Klein T, Münzel T, Daiber A.
    Cardiovasc Res; 2012 Oct 01; 96(1):140-9. PubMed ID: 22843705
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  • 15. Linagliptin, a dipeptidyl peptidase-4 inhibitor in development for the treatment of type 2 diabetes mellitus: a Phase I, randomized, double-blind, placebo-controlled trial of single and multiple escalating doses in healthy adult male Japanese subjects.
    Sarashina A, Sesoko S, Nakashima M, Hayashi N, Taniguchi A, Horie Y, Graefe-Mody EU, Woerle HJ, Dugi KA.
    Clin Ther; 2010 Jun 01; 32(6):1188-204. PubMed ID: 20637971
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  • 16. Improved outcome of islet transplantation in partially pancreatectomized diabetic mice by inhibition of dipeptidyl peptidase-4 with sitagliptin.
    Kim YS, Oh SH, Park KS, No H, Oh BJ, Kim SK, Jung HS, Kim JH, Lee MS, Lee MK, Kim KW.
    Pancreas; 2011 Aug 01; 40(6):855-60. PubMed ID: 21747318
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