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Journal Abstract Search

159 related items for PubMed ID: 22775490

  • 1. Bioactivation of chlorpyrifos by CYP2B6 variants.
    Crane AL, Klein K, Olson JR.
    Xenobiotica; 2012 Dec; 42(12):1255-62. PubMed ID: 22775490
    [Abstract] [Full Text] [Related]

  • 2. Effect of CYP2B6*6 and CYP2C19*2 genotype on chlorpyrifos metabolism.
    Crane AL, Klein K, Zanger UM, Olson JR.
    Toxicology; 2012 Mar 11; 293(1-3):115-122. PubMed ID: 22281205
    [Abstract] [Full Text] [Related]

  • 3. Effects of the CYP2B6*6 allele on catalytic properties and inhibition of CYP2B6 in vitro: implication for the mechanism of reduced efavirenz metabolism and other CYP2B6 substrates in vivo.
    Xu C, Ogburn ET, Guo Y, Desta Z.
    Drug Metab Dispos; 2012 Apr 11; 40(4):717-25. PubMed ID: 22232427
    [Abstract] [Full Text] [Related]

  • 4. Functional characterization of CYP2B6 allelic variants in demethylation of antimalarial artemether.
    Honda M, Muroi Y, Tamaki Y, Saigusa D, Suzuki N, Tomioka Y, Matsubara Y, Oda A, Hirasawa N, Hiratsuka M.
    Drug Metab Dispos; 2011 Oct 11; 39(10):1860-5. PubMed ID: 21746968
    [Abstract] [Full Text] [Related]

  • 5. Human variation in CYP-specific chlorpyrifos metabolism.
    Croom EL, Wallace AD, Hodgson E.
    Toxicology; 2010 Oct 29; 276(3):184-91. PubMed ID: 20709133
    [Abstract] [Full Text] [Related]

  • 6. Role of polymorphic human CYP2B6 in cyclophosphamide bioactivation.
    Xie HJ, Yasar U, Lundgren S, Griskevicius L, Terelius Y, Hassan M, Rane A.
    Pharmacogenomics J; 2003 Oct 29; 3(1):53-61. PubMed ID: 12629583
    [Abstract] [Full Text] [Related]

  • 7. Functional characterization of cytochrome P450 2B6 allelic variants.
    Jinno H, Tanaka-Kagawa T, Ohno A, Makino Y, Matsushima E, Hanioka N, Ando M.
    Drug Metab Dispos; 2003 Apr 29; 31(4):398-403. PubMed ID: 12642465
    [Abstract] [Full Text] [Related]

  • 8. Polymorphic variants of cytochrome P450 2B6 (CYP2B6.4-CYP2B6.9) exhibit altered rates of metabolism for bupropion and efavirenz: a charge-reversal mutation in the K139E variant (CYP2B6.8) impairs formation of a functional cytochrome p450-reductase complex.
    Zhang H, Sridar C, Kenaan C, Amunugama H, Ballou DP, Hollenberg PF.
    J Pharmacol Exp Ther; 2011 Sep 29; 338(3):803-9. PubMed ID: 21659470
    [Abstract] [Full Text] [Related]

  • 9. In vitro age-dependent enzymatic metabolism of chlorpyrifos and chlorpyrifos-oxon in human hepatic microsomes and chlorpyrifos-oxon in plasma.
    Smith JN, Timchalk C, Bartels MJ, Poet TS.
    Drug Metab Dispos; 2011 Aug 29; 39(8):1353-62. PubMed ID: 21521795
    [Abstract] [Full Text] [Related]

  • 10. The influence of sex, ethnicity, and CYP2B6 genotype on bupropion metabolism as an index of hepatic CYP2B6 activity in humans.
    Ilic K, Hawke RL, Thirumaran RK, Schuetz EG, Hull JH, Kashuba AD, Stewart PW, Lindley CM, Chen ML.
    Drug Metab Dispos; 2013 Mar 29; 41(3):575-81. PubMed ID: 23238783
    [Abstract] [Full Text] [Related]

  • 11. Metabolism of endosulfan-alpha by human liver microsomes and its utility as a simultaneous in vitro probe for CYP2B6 and CYP3A4.
    Casabar RC, Wallace AD, Hodgson E, Rose RL.
    Drug Metab Dispos; 2006 Oct 29; 34(10):1779-85. PubMed ID: 16855053
    [Abstract] [Full Text] [Related]

  • 12. Functional characterization of 26 CYP2B6 allelic variants (CYP2B6.2-CYP2B6.28, except CYP2B6.22).
    Watanabe T, Sakuyama K, Sasaki T, Ishii Y, Ishikawa M, Hirasawa N, Hiratsuka M.
    Pharmacogenet Genomics; 2010 Jul 29; 20(7):459-62. PubMed ID: 20517174
    [Abstract] [Full Text] [Related]

  • 13. Examination of purported probes of human CYP2B6.
    Ekins S, VandenBranden M, Ring BJ, Wrighton SA.
    Pharmacogenetics; 1997 Jun 29; 7(3):165-79. PubMed ID: 9241656
    [Abstract] [Full Text] [Related]

  • 14. The combined impact of CYP2C19 and CYP2B6 pharmacogenetics on cyclophosphamide bioactivation.
    Helsby NA, Hui CY, Goldthorpe MA, Coller JK, Soh MC, Gow PJ, De Zoysa JZ, Tingle MD.
    Br J Clin Pharmacol; 2010 Dec 29; 70(6):844-53. PubMed ID: 21175440
    [Abstract] [Full Text] [Related]

  • 15. Hepatic CYP2B6 expression: gender and ethnic differences and relationship to CYP2B6 genotype and CAR (constitutive androstane receptor) expression.
    Lamba V, Lamba J, Yasuda K, Strom S, Davila J, Hancock ML, Fackenthal JD, Rogan PK, Ring B, Wrighton SA, Schuetz EG.
    J Pharmacol Exp Ther; 2003 Dec 29; 307(3):906-22. PubMed ID: 14551287
    [Abstract] [Full Text] [Related]

  • 16. Effect of genetic polymorphism of human CYP2B6 on the metabolic activation of chlorpyrifos.
    Imaishi H, Goto T.
    Pestic Biochem Physiol; 2018 Jan 29; 144():42-48. PubMed ID: 29463407
    [Abstract] [Full Text] [Related]

  • 17. Multiple novel nonsynonymous CYP2B6 gene polymorphisms in Caucasians: demonstration of phenotypic null alleles.
    Lang T, Klein K, Richter T, Zibat A, Kerb R, Eichelbaum M, Schwab M, Zanger UM.
    J Pharmacol Exp Ther; 2004 Oct 29; 311(1):34-43. PubMed ID: 15190123
    [Abstract] [Full Text] [Related]

  • 18. Cytochrome P450-specific human PBPK/PD models for the organophosphorus pesticides: chlorpyrifos and parathion.
    Foxenberg RJ, Ellison CA, Knaak JB, Ma C, Olson JR.
    Toxicology; 2011 Jul 11; 285(1-2):57-66. PubMed ID: 21514354
    [Abstract] [Full Text] [Related]

  • 19. Identification of the human cytochrome P450 enzymes involved in the two oxidative steps in the bioactivation of clopidogrel to its pharmacologically active metabolite.
    Kazui M, Nishiya Y, Ishizuka T, Hagihara K, Farid NA, Okazaki O, Ikeda T, Kurihara A.
    Drug Metab Dispos; 2010 Jan 11; 38(1):92-9. PubMed ID: 19812348
    [Abstract] [Full Text] [Related]

  • 20. Substrate specificity, regulation, and polymorphism of human cytochrome P450 2B6.
    Mo SL, Liu YH, Duan W, Wei MQ, Kanwar JR, Zhou SF.
    Curr Drug Metab; 2009 Sep 11; 10(7):730-53. PubMed ID: 19702527
    [Abstract] [Full Text] [Related]

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