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2. Role of RhoA activation in the growth and morphology of a murine prostate tumor cell line. Ghosh PM, Ghosh-Choudhury N, Moyer ML, Mott GE, Thomas CA, Foster BA, Greenberg NM, Kreisberg JI. Oncogene; 1999 Jul 15; 18(28):4120-30. PubMed ID: 10435593 [Abstract] [Full Text] [Related]
3. MEK and ERK activation in ras-disabled RBL-2H3 mast cells and novel roles for geranylgeranylated and farnesylated proteins in Fc epsilonRI-mediated signaling. Graham TE, Pfeiffer JR, Lee RJ, Kusewitt DF, Martinez AM, Foutz T, Wilson BS, Oliver JM. J Immunol; 1998 Dec 15; 161(12):6733-44. PubMed ID: 9862703 [Abstract] [Full Text] [Related]
4. Basic fibroblast growth factor mediated growth inhibition in breast cancer cells is independent of ras signaling pathway. Fenig E, Szyper-Kravitz M, Yerushalmi R, Lahav M, Beery E, Wasserman L, Gutman H, Nordenberg J. Oncol Rep; 2002 Dec 15; 9(4):875-7. PubMed ID: 12066225 [Abstract] [Full Text] [Related]
5. Lovastatin, a cholesterol biosynthesis inhibitor, inhibits the growth of human H-ras oncogene transformed cells in nude mice. Sebti SM, Tkalcevic GT, Jani JP. Cancer Commun; 1991 May 15; 3(5):141-7. PubMed ID: 2043425 [Abstract] [Full Text] [Related]
6. Inhibitors of Ras farnesylation revert the increased resistance to oxidative stress in K-Ras transformed NIH 3T3 cells. Santillo M, Mondola P, Gioielli A, Serù R, Iossa S, Annella T, Vitale M, Bifulco M. Biochem Biophys Res Commun; 1996 Dec 24; 229(3):739-45. PubMed ID: 8954966 [Abstract] [Full Text] [Related]
7. Geranylgeraniol potentiates lovastatin inhibition of oncogenic H-Ras processing and signaling while preventing cytotoxicity. McGuire TF, Sebti SM. Oncogene; 1997 Jan 23; 14(3):305-12. PubMed ID: 9018116 [Abstract] [Full Text] [Related]
8. Inhibition of Ras farnesylation by lovastatin leads to downregulation of proliferation and migration in primary cultured human glioblastoma cells. Bouterfa HL, Sattelmeyer V, Czub S, Vordermark D, Roosen K, Tonn JC. Anticancer Res; 2000 Jan 23; 20(4):2761-71. PubMed ID: 10953355 [Abstract] [Full Text] [Related]
9. Regulation of proliferation and Ras localization in transformed cells by products of mevalonate metabolism. Cuthbert JA, Lipsky PE. Cancer Res; 1997 Aug 15; 57(16):3498-505. PubMed ID: 9270019 [Abstract] [Full Text] [Related]
10. Inhibition of B16 melanoma cell proliferation and alterations in p21 ras expression induced by interceptors of signal transduction pathways. Nordenberg J, Goldwasser I, Zoref-Shani E, Beery E, Sidi Y. Isr J Med Sci; 1996 Dec 15; 32(12):1153-7. PubMed ID: 9007143 [Abstract] [Full Text] [Related]
11. Protection against malignant conversion in SENCAR mouse skin by all trans retinoic acid: inhibition of the ras p21-processing enzyme farnesyltransferase and Ha-ras p21 membrane localization. Agarwal R, Mohan RR, Ahmad N, Mukhtar H. Mol Carcinog; 1996 Sep 15; 17(1):13-22. PubMed ID: 8876671 [Abstract] [Full Text] [Related]
12. Reversal of ras-induced inhibition of gap-junctional intercellular communication, transformation, and tumorigenesis by lovastatin. Ruch RJ, Madhukar BV, Trosko JE, Klaunig JE. Mol Carcinog; 1993 Sep 15; 7(1):50-9. PubMed ID: 8435109 [Abstract] [Full Text] [Related]
13. Farnesylation of p21 Ras proteins in Xenopus oocytes. Zhao J, Kung HF, Manne V. Cell Mol Biol Res; 1994 Sep 15; 40(4):313-21. PubMed ID: 7866432 [Abstract] [Full Text] [Related]
14. [In vitro effect of lovastatin on NB4 promyelocytic leukemia cells]. Guo F, Cen J, Chen Z. Zhonghua Xue Ye Xue Za Zhi; 2001 Nov 15; 22(11):584-8. PubMed ID: 11855147 [Abstract] [Full Text] [Related]
15. ras isoprenylation is required for ras-induced but not for NGF-induced neuronal differentiation of PC12 cells. Qiu MS, Pitts AF, Winters TR, Green SH. J Cell Biol; 1991 Nov 15; 115(3):795-808. PubMed ID: 1918164 [Abstract] [Full Text] [Related]
16. [Inhibitors of isoprenylation of ras p21]. Yoshimatsu K. Gan To Kagaku Ryoho; 1997 Sep 15; 24(11):1495-502. PubMed ID: 9309147 [Abstract] [Full Text] [Related]
17. Lovastatin inhibits oxidized low-density lipoprotein-induced plasminogen activator inhibitor and transforming growth factor-beta1 expression via a decrease in Ras/extracellular signal-regulated kinase activity in mesangial cells. Song CY, Kim BC, Lee HS. Transl Res; 2008 Jan 15; 151(1):27-35. PubMed ID: 18061125 [Abstract] [Full Text] [Related]
18. Geranylgeranyl as well as farnesyl moiety is transferred to Ras p21 overproduced in adrenocortical cells transformed by c-Ha-rasEJ oncogene. Osman H, Mazet JL, Maume G, Maume BF. Biochem Biophys Res Commun; 1997 Feb 24; 231(3):789-92. PubMed ID: 9070894 [Abstract] [Full Text] [Related]
19. Lovastatin induces apoptosis in a primitive neuroectodermal tumor cell line in association with RB down-regulation and loss of the G1 checkpoint. Kim JS, Pirnia F, Choi YH, Nguyen PM, Knepper B, Tsokos M, Schulte TW, Birrer MJ, Blagosklonny MV, Schaefer O, Mushinski JF, Trepel JB. Oncogene; 2000 Dec 07; 19(52):6082-90. PubMed ID: 11146561 [Abstract] [Full Text] [Related]