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229 related items for PubMed ID: 22800886

  • 1. LRP16 gene protects mouse insulinoma MIN6 cells against fatty acid-induced apoptosis through Akt/FoxO1 signaling.
    Li XJ, Guo QH, Wang X, Xue B, Sun LQ, Meng QT, Lu JM, Mu YM.
    Chin Med J (Engl); 2012 May; 125(10):1695-702. PubMed ID: 22800886
    [Abstract] [Full Text] [Related]

  • 2. Curcumin attenuates palmitate-induced apoptosis in MIN6 pancreatic β-cells through PI3K/Akt/FoxO1 and mitochondrial survival pathways.
    Hao F, Kang J, Cao Y, Fan S, Yang H, An Y, Pan Y, Tie L, Li X.
    Apoptosis; 2015 Nov; 20(11):1420-32. PubMed ID: 26330141
    [Abstract] [Full Text] [Related]

  • 3. Inhibition of Foxo1 protects pancreatic islet beta-cells against fatty acid and endoplasmic reticulum stress-induced apoptosis.
    Martinez SC, Tanabe K, Cras-Méneur C, Abumrad NA, Bernal-Mizrachi E, Permutt MA.
    Diabetes; 2008 Apr; 57(4):846-59. PubMed ID: 18174526
    [Abstract] [Full Text] [Related]

  • 4. Inhibition of Foxo1 mediates protective effects of ghrelin against lipotoxicity in MIN6 pancreatic beta-cells.
    Wang W, Liu Y, Chen Y, Cao C, Xiang Y, Zhang D, Han L, Zhao H, Liu G.
    Peptides; 2010 Feb; 31(2):307-14. PubMed ID: 19944124
    [Abstract] [Full Text] [Related]

  • 5. Reduced expression of the LRP16 gene in mouse insulinoma (MIN6) cells exerts multiple effects on insulin content, proliferation and apoptosis.
    Li X, Xue B, Wang X, Sun L, Zhang T, Qu L, Zou X, Mu Y.
    J Huazhong Univ Sci Technolog Med Sci; 2012 Apr; 32(2):190-198. PubMed ID: 22528219
    [Abstract] [Full Text] [Related]

  • 6. Forkhead box O1/pancreatic and duodenal homeobox 1 intracellular translocation is regulated by c-Jun N-terminal kinase and involved in prostaglandin E2-induced pancreatic beta-cell dysfunction.
    Meng Z, Lv J, Luo Y, Lin Y, Zhu Y, Nie J, Yang T, Sun Y, Han X.
    Endocrinology; 2009 Dec; 150(12):5284-93. PubMed ID: 19837872
    [Abstract] [Full Text] [Related]

  • 7. Banxia Xiexin Decoction Ameliorates t-BHP-Induced Apoptosis in Pancreatic Beta Cells by Activating the PI3K/AKT/FOXO1 Signaling Pathway.
    Du LJ, Pang B, Tan YM, Yang YN, Zhang MZ, Pang Q, Sun M, Ni Q.
    J Diabetes Res; 2020 Dec; 2020():3695689. PubMed ID: 32377518
    [Abstract] [Full Text] [Related]

  • 8. Glucose regulates Foxo1 through insulin receptor signaling in the pancreatic islet beta-cell.
    Martinez SC, Cras-Méneur C, Bernal-Mizrachi E, Permutt MA.
    Diabetes; 2006 Jun; 55(6):1581-91. PubMed ID: 16731820
    [Abstract] [Full Text] [Related]

  • 9. Protective action of liraglutide in beta cells under lipotoxic stress via PI3K/Akt/FoxO1 pathway.
    Shao S, Nie M, Chen C, Chen X, Zhang M, Yuan G, Yu X, Yang Y.
    J Cell Biochem; 2014 Jun; 115(6):1166-75. PubMed ID: 24415347
    [Abstract] [Full Text] [Related]

  • 10. Regulation of forkhead box O1 (FOXO1) by protein kinase B and glucocorticoids: different mechanisms of induction of beta cell death in vitro.
    Kaiser G, Gerst F, Michael D, Berchtold S, Friedrich B, Strutz-Seebohm N, Lang F, Häring HU, Ullrich S.
    Diabetologia; 2013 Jul; 56(7):1587-95. PubMed ID: 23435785
    [Abstract] [Full Text] [Related]

  • 11. Protein tyrosine phosphatase 1B inhibition ameliorates palmitate-induced mitochondrial dysfunction and apoptosis in skeletal muscle cells.
    Taheripak G, Bakhtiyari S, Rajabibazl M, Pasalar P, Meshkani R.
    Free Radic Biol Med; 2013 Dec; 65():1435-1446. PubMed ID: 24120971
    [Abstract] [Full Text] [Related]

  • 12. [LRP16 gene causes insulin resistance in C2-C12 cells by inhibiting the IRS-1 signaling and the transcriptional activity of peroxisome proliferator actived receptor γ].
    Zang L, Mu YM, Lü ZH, Xue B, Ma XL, Yang GQ, Ba JM, Dou JT, Lu JM.
    Zhonghua Yi Xue Za Zhi; 2011 May 31; 91(20):1408-12. PubMed ID: 21756814
    [Abstract] [Full Text] [Related]

  • 13. PGC-1alpha gene expression is down-regulated by Akt- mediated phosphorylation and nuclear exclusion of FoxO1 in insulin-stimulated skeletal muscle.
    Southgate RJ, Bruce CR, Carey AL, Steinberg GR, Walder K, Monks R, Watt MJ, Hawley JA, Birnbaum MJ, Febbraio MA.
    FASEB J; 2005 Dec 31; 19(14):2072-4. PubMed ID: 16203862
    [Abstract] [Full Text] [Related]

  • 14. FoxO proteins' nuclear retention and BH3-only protein Bim induction evoke mitochondrial dysfunction-mediated apoptosis in berberine-treated HepG2 cells.
    Shukla S, Rizvi F, Raisuddin S, Kakkar P.
    Free Radic Biol Med; 2014 Nov 31; 76():185-99. PubMed ID: 25128467
    [Abstract] [Full Text] [Related]

  • 15. Up-regulation of LRP16 mRNA by 17beta-estradiol through activation of estrogen receptor alpha (ERalpha), but not ERbeta, and promotion of human breast cancer MCF-7 cell proliferation: a preliminary report.
    Han WD, Mu YM, Lu XC, Xu ZM, Li XJ, Yu L, Song HJ, Li M, Lu JM, Zhao YL, Pan CY.
    Endocr Relat Cancer; 2003 Jun 31; 10(2):217-24. PubMed ID: 12790785
    [Abstract] [Full Text] [Related]

  • 16. Nucleo-cytosolic shuttling of FoxO1 directly regulates mouse Ins2 but not Ins1 gene expression in pancreatic beta cells (MIN6).
    Meur G, Qian Q, da Silva Xavier G, Pullen TJ, Tsuboi T, McKinnon C, Fletcher L, Tavaré JM, Hughes S, Johnson P, Rutter GA.
    J Biol Chem; 2011 Apr 15; 286(15):13647-56. PubMed ID: 21335550
    [Abstract] [Full Text] [Related]

  • 17. Glucose-dependent insulinotropic polypeptide (GIP) stimulation of pancreatic beta-cell survival is dependent upon phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) signaling, inactivation of the forkhead transcription factor Foxo1, and down-regulation of bax expression.
    Kim SJ, Winter K, Nian C, Tsuneoka M, Koda Y, McIntosh CH.
    J Biol Chem; 2005 Jun 10; 280(23):22297-307. PubMed ID: 15817464
    [Abstract] [Full Text] [Related]

  • 18. Tacrolimus inhibits insulin release and promotes apoptosis of Min6 cells through the inhibition of the PI3K/Akt/mTOR pathway.
    Tong L, Li W, Zhang Y, Zhou F, Zhao Y, Zhao L, Liu J, Song Z, Yu M, Zhou C, Yu A.
    Mol Med Rep; 2021 Sep 10; 24(3):. PubMed ID: 34278483
    [Abstract] [Full Text] [Related]

  • 19. Endurance exercise training increases APPL1 expression and improves insulin signaling in the hepatic tissue of diet-induced obese mice, independently of weight loss.
    Marinho R, Ropelle ER, Cintra DE, De Souza CT, Da Silva AS, Bertoli FC, Colantonio E, D'Almeida V, Pauli JR.
    J Cell Physiol; 2012 Jul 10; 227(7):2917-26. PubMed ID: 21938726
    [Abstract] [Full Text] [Related]

  • 20. Protection against glucocorticoid-induced damage in human tenocytes by modulation of ERK, Akt, and forkhead signaling.
    Poulsen RC, Carr AJ, Hulley PA.
    Endocrinology; 2011 Feb 10; 152(2):503-14. PubMed ID: 21209015
    [Abstract] [Full Text] [Related]


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