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Journal Abstract Search

429 related items for PubMed ID: 22821713

  • 1. Synergistic regulation of p53 by Mdm2 and Mdm4 is critical in cardiac endocardial cushion morphogenesis during heart development.
    Zhang Q, He X, Chen L, Zhang C, Gao X, Yang Z, Liu G.
    J Pathol; 2012 Nov; 228(3):416-28. PubMed ID: 22821713
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  • 2. Tissue-specific differences of p53 inhibition by Mdm2 and Mdm4.
    Grier JD, Xiong S, Elizondo-Fraire AC, Parant JM, Lozano G.
    Mol Cell Biol; 2006 Jan; 26(1):192-8. PubMed ID: 16354690
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  • 3. Synergistic roles of Mdm2 and Mdm4 for p53 inhibition in central nervous system development.
    Xiong S, Van Pelt CS, Elizondo-Fraire AC, Liu G, Lozano G.
    Proc Natl Acad Sci U S A; 2006 Feb 28; 103(9):3226-31. PubMed ID: 16492743
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  • 7. Regulation of MDM4 (MDMX) function by p76(MDM2): a new facet in the control of p53 activity.
    Giglio S, Mancini F, Pellegrino M, Di Conza G, Puxeddu E, Sacchi A, Pontecorvi A, Moretti F.
    Oncogene; 2010 Nov 04; 29(44):5935-45. PubMed ID: 20697359
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  • 8. Mdm2 and Mdm4 loss regulates distinct p53 activities.
    Barboza JA, Iwakuma T, Terzian T, El-Naggar AK, Lozano G.
    Mol Cancer Res; 2008 Jun 04; 6(6):947-54. PubMed ID: 18567799
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  • 9. Rescue of Mdm4-deficient mice by Mdm2 reveals functional overlap of Mdm2 and Mdm4 in development.
    Steinman HA, Hoover KM, Keeler ML, Sands AT, Jones SN.
    Oncogene; 2005 Nov 24; 24(53):7935-40. PubMed ID: 16027727
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  • 12. Mdm2, but not Mdm4, protects terminally differentiated smooth muscle cells from p53-mediated caspase-3-independent cell death.
    Boesten LS, Zadelaar SM, De Clercq S, Francoz S, van Nieuwkoop A, Biessen EA, Hofmann F, Feil S, Feil R, Jochemsen AG, Zurcher C, Havekes LM, van Vlijmen BJ, Marine JC.
    Cell Death Differ; 2006 Dec 24; 13(12):2089-98. PubMed ID: 16729027
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  • 13. Loss of Mdm4 results in p53-dependent dilated cardiomyopathy.
    Xiong S, Van Pelt CS, Elizondo-Fraire AC, Fernandez-Garcia B, Lozano G.
    Circulation; 2007 Jun 12; 115(23):2925-30. PubMed ID: 17533180
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  • 15. Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53.
    Parant J, Chavez-Reyes A, Little NA, Yan W, Reinke V, Jochemsen AG, Lozano G.
    Nat Genet; 2001 Sep 12; 29(1):92-5. PubMed ID: 11528400
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  • 18. Heterodimerization of Mdm2 and Mdm4 is critical for regulating p53 activity during embryogenesis but dispensable for p53 and Mdm2 stability.
    Pant V, Xiong S, Iwakuma T, Quintás-Cardama A, Lozano G.
    Proc Natl Acad Sci U S A; 2011 Jul 19; 108(29):11995-2000. PubMed ID: 21730132
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  • 19. Mutation at p53 serine 389 does not rescue the embryonic lethality in mdm2 or mdm4 null mice.
    Iwakuma T, Parant JM, Fasulo M, Zwart E, Jacks T, de Vries A, Lozano G.
    Oncogene; 2004 Oct 07; 23(46):7644-50. PubMed ID: 15361844
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  • 20. MDM2 but not MDM4 promotes retinoblastoma cell proliferation through p53-independent regulation of MYCN translation.
    Qi DL, Cobrinik D.
    Oncogene; 2017 Mar 30; 36(13):1760-1769. PubMed ID: 27748758
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