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248 related items for PubMed ID: 22839733

  • 1. 2C-Methyl-d-erythritol 4-phosphate enhances and sustains cyclodiphosphate synthase IspF activity.
    Bitok JK, Meyers CF.
    ACS Chem Biol; 2012 Oct 19; 7(10):1702-10. PubMed ID: 22839733
    [Abstract] [Full Text] [Related]

  • 2. Crystal structure of IspF from Bacillus subtilis and absence of protein complex assembly amongst IspD/IspE/IspF enzymes in the MEP pathway.
    Liu Z, Jin Y, Liu W, Tao Y, Wang G.
    Biosci Rep; 2018 Feb 28; 38(1):. PubMed ID: 29335298
    [Abstract] [Full Text] [Related]

  • 3. Methylerythritol phosphate pathway to isoprenoids: kinetic modeling and in silico enzyme inhibitions in Plasmodium falciparum.
    Singh VK, Ghosh I.
    FEBS Lett; 2013 Sep 02; 587(17):2806-17. PubMed ID: 23816706
    [Abstract] [Full Text] [Related]

  • 4. Synthesis of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate and kinetic studies of Mycobacterium tuberculosis IspF.
    Narayanasamy P, Eoh H, Brennan PJ, Crick DC.
    Chem Biol; 2010 Feb 26; 17(2):117-22. PubMed ID: 20189102
    [Abstract] [Full Text] [Related]

  • 5. Biosynthesis of isoprenoids: a bifunctional IspDF enzyme from Campylobacter jejuni.
    Gabrielsen M, Rohdich F, Eisenreich W, Gräwert T, Hecht S, Bacher A, Hunter WN.
    Eur J Biochem; 2004 Jul 26; 271(14):3028-35. PubMed ID: 15233799
    [Abstract] [Full Text] [Related]

  • 6. Crystal structures of IspF from Plasmodium falciparum and Burkholderia cenocepacia: comparisons inform antimicrobial drug target assessment.
    O'Rourke PE, Kalinowska-Tłuścik J, Fyfe PK, Dawson A, Hunter WN.
    BMC Struct Biol; 2014 Jan 10; 14():1. PubMed ID: 24410837
    [Abstract] [Full Text] [Related]

  • 7. Biosynthesis of terpenoids. 2C-Methyl-D-erythritol 2,4-cyclodiphosphate synthase (IspF) from Plasmodium falciparum.
    Rohdich F, Eisenreich W, Wungsintaweekul J, Hecht S, Schuhr CA, Bacher A.
    Eur J Biochem; 2001 Jun 10; 268(11):3190-7. PubMed ID: 11389720
    [Abstract] [Full Text] [Related]

  • 8. Feedback inhibition of deoxy-D-xylulose-5-phosphate synthase regulates the methylerythritol 4-phosphate pathway.
    Banerjee A, Wu Y, Banerjee R, Li Y, Yan H, Sharkey TD.
    J Biol Chem; 2013 Jun 07; 288(23):16926-16936. PubMed ID: 23612965
    [Abstract] [Full Text] [Related]

  • 9. Structure of 2C-methyl-d-erythritol-2,4-cyclodiphosphate synthase involved in mevalonate-independent biosynthesis of isoprenoids.
    Steinbacher S, Kaiser J, Wungsintaweekul J, Hecht S, Eisenreich W, Gerhardt S, Bacher A, Rohdich F.
    J Mol Biol; 2002 Feb 08; 316(1):79-88. PubMed ID: 11829504
    [Abstract] [Full Text] [Related]

  • 10. Escherichia coli engineered to synthesize isopentenyl diphosphate and dimethylallyl diphosphate from mevalonate: a novel system for the genetic analysis of the 2-C-methyl-d-erythritol 4-phosphate pathway for isoprenoid biosynthesis.
    Campos N, Rodríguez-Concepción M, Sauret-Güeto S, Gallego F, Lois LM, Boronat A.
    Biochem J; 2001 Jan 01; 353(Pt 1):59-67. PubMed ID: 11115399
    [Abstract] [Full Text] [Related]

  • 11. A single nucleotide mutation of IspF gene involved in the MEP pathway for isoprenoid biosynthesis causes yellow-green leaf phenotype in rice.
    Huang R, Wang Y, Wang P, Li C, Xiao F, Chen N, Li N, Li C, Sun C, Li L, Chen R, Xu Z, Zhu J, Deng X.
    Plant Mol Biol; 2018 Jan 01; 96(1-2):5-16. PubMed ID: 29143298
    [Abstract] [Full Text] [Related]

  • 12. Functional evidence for the involvement of Arabidopsis IspF homolog in the nonmevalonate pathway of plastid isoprenoid biosynthesis.
    Hsieh MH, Goodman HM.
    Planta; 2006 Mar 01; 223(4):779-84. PubMed ID: 16231155
    [Abstract] [Full Text] [Related]

  • 13. Antibacterial activity of 2-amino-4-hydroxypyrimidine-5-carboxylates and binding to Burkholderia pseudomallei 2-C-methyl-d-erythritol-2,4-cyclodiphosphate synthase.
    Watkins SM, Ghose D, Blain JM, Grote DL, Luan CH, Clare M, Meganathan R, Horn JR, Hagen TJ.
    Bioorg Med Chem Lett; 2019 Oct 15; 29(20):126660. PubMed ID: 31521478
    [Abstract] [Full Text] [Related]

  • 14. The identification of isoprenoids that bind in the intersubunit cavity of Escherichia coli 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase by complementary biophysical methods.
    Kemp LE, Alphey MS, Bond CS, Ferguson MA, Hecht S, Bacher A, Eisenreich W, Rohdich F, Hunter WN.
    Acta Crystallogr D Biol Crystallogr; 2005 Jan 15; 61(Pt 1):45-52. PubMed ID: 15608374
    [Abstract] [Full Text] [Related]

  • 15. Development of inhibitors of the 2C-methyl-D-erythritol 4-phosphate (MEP) pathway enzymes as potential anti-infective agents.
    Masini T, Hirsch AK.
    J Med Chem; 2014 Dec 11; 57(23):9740-63. PubMed ID: 25210872
    [Abstract] [Full Text] [Related]

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  • 17. Cloning and expression of IspDF from Mesorhizobium loti. Characterization of a bifunctional protein that catalyzes non-consecutive steps in the methylerythritol phosphate pathway.
    Testa CA, Lherbet C, Pojer F, Noel JP, Poulter CD.
    Biochim Biophys Acta; 2006 Jan 11; 1764(1):85-96. PubMed ID: 16203191
    [Abstract] [Full Text] [Related]

  • 18. Biosynthesis of terpenoids: YgbB protein converts 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate to 2C-methyl-D-erythritol 2,4-cyclodiphosphate.
    Herz S, Wungsintaweekul J, Schuhr CA, Hecht S, Luttgen H, Sagner S, Fellermeier M, Eisenreich W, Zenk MH, Bacher A, Rohdich F.
    Proc Natl Acad Sci U S A; 2000 Mar 14; 97(6):2486-90. PubMed ID: 10694574
    [Abstract] [Full Text] [Related]

  • 19. Structure of 2C-methyl-D-erythritol 2,4- cyclodiphosphate synthase: an essential enzyme for isoprenoid biosynthesis and target for antimicrobial drug development.
    Kemp LE, Bond CS, Hunter WN.
    Proc Natl Acad Sci U S A; 2002 May 14; 99(10):6591-6. PubMed ID: 11997478
    [Abstract] [Full Text] [Related]

  • 20. Studies on the nonmevalonate pathway of terpene biosynthesis. The role of 2C-methyl-D-erythritol 2,4-cyclodiphosphate in plants.
    Fellermeier M, Raschke M, Sagner S, Wungsintaweekul J, Schuhr CA, Hecht S, Kis K, Radykewicz T, Adam P, Rohdich F, Eisenreich W, Bacher A, Arigoni D, Zenk MH.
    Eur J Biochem; 2001 Dec 14; 268(23):6302-10. PubMed ID: 11733027
    [Abstract] [Full Text] [Related]

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